SGC707
- $32 - $1800
- Product name: SGC707
- CAS: 1687736-54-4
- MF: C16H18N4O2
- MW: 298.34
- EINECS:
- MDL Number:MFCD28411624
- Synonyms:SGC707;N-6-Isoquinolinyl-N'-[2-oxo-2-(1-pyrrolidinyl)ethyl]urea;SGC 707;SGC707;CS-2192;Urea, N-6-isoquinolinyl-N'-[2-oxo-2-(1-pyrrolidinyl)ethyl]-;S C 707
21 prices
Selected condition:
Brand
- AK Scientific
- ApexBio Technology
- Axon Medchem
- Biorbyt Ltd
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Tocris
- TRC
Package
- 50
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 500mg
- 1g
- ManufacturerAK Scientific
- Product number4586EB
- Product description1-Isoquinolin-6-Yl-3-[2-Oxo-2-(Pyrrolidin-1-Yl)ethyl]urea
- Packaging100mg
- Price$1064
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB6048
- Product descriptionSGC707
- Packaging10mg
- Price$75
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon2945
- Product descriptionSGC707 99%
- Packaging10mg
- Price$99
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb545936
- Product descriptionSGC-707 >98%
- Packaging5mg
- Price$181.9
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb545936
- Product descriptionSGC-707 >98%
- Packaging25mg
- Price$489.6
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number17017
- Product descriptionSGC707 ≥98%
- Packaging1mg
- Price$32
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17017
- Product descriptionSGC707 ≥98%
- Packaging10mg
- Price$169
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17017
- Product descriptionSGC707 ≥98%
- Packaging25mg
- Price$381
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17017
- Product descriptionSGC707 ≥98%
- Packaging50mg
- Price$669
- Updated2024-03-01
- Buy
- ManufacturerChemenu
- Product numberCM250198
- Product description1-(Isoquinolin-6-yl)-3-(2-oxo-2-(pyrrolidin-1-yl)ethyl)urea 98%
- Packaging100mg
- Price$539
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-5370
- Product descriptionSGC707 99.31%
- Packaging10mg
- Price$65
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-5370
- Product descriptionSGC707 99.31%
- Packaging50mg
- Price$225
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-5370
- Product descriptionSGC707 99.31%
- Packaging100mg
- Price$450
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-5370
- Product descriptionSGC707 99.31%
- Packaging500mg
- Price$1750
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31003034
- Product descriptionSGC707 98+%
- Packaging50mg
- Price$375
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31003034
- Product descriptionSGC707 98+%
- Packaging100mg
- Price$681
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AK Scientific | 4586EB | 1-Isoquinolin-6-Yl-3-[2-Oxo-2-(Pyrrolidin-1-Yl)ethyl]urea | 100mg | $1064 | 2021-12-16 | Buy |
ApexBio Technology | B6048 | SGC707 | 10mg | $75 | 2021-12-16 | Buy |
Axon Medchem | Axon2945 | SGC707 99% | 10mg | $99 | 2021-12-16 | Buy |
Biorbyt Ltd | orb545936 | SGC-707 >98% | 5mg | $181.9 | 2021-12-16 | Buy |
Biorbyt Ltd | orb545936 | SGC-707 >98% | 25mg | $489.6 | 2021-12-16 | Buy |
Cayman Chemical | 17017 | SGC707 ≥98% | 1mg | $32 | 2024-03-01 | Buy |
Cayman Chemical | 17017 | SGC707 ≥98% | 10mg | $169 | 2024-03-01 | Buy |
Cayman Chemical | 17017 | SGC707 ≥98% | 25mg | $381 | 2024-03-01 | Buy |
Cayman Chemical | 17017 | SGC707 ≥98% | 50mg | $669 | 2024-03-01 | Buy |
Chemenu | CM250198 | 1-(Isoquinolin-6-yl)-3-(2-oxo-2-(pyrrolidin-1-yl)ethyl)urea 98% | 100mg | $539 | 2021-12-16 | Buy |
ChemScene | CS-5370 | SGC707 99.31% | 10mg | $65 | 2021-12-16 | Buy |
ChemScene | CS-5370 | SGC707 99.31% | 50mg | $225 | 2021-12-16 | Buy |
ChemScene | CS-5370 | SGC707 99.31% | 100mg | $450 | 2021-12-16 | Buy |
ChemScene | CS-5370 | SGC707 99.31% | 500mg | $1750 | 2021-12-16 | Buy |
Crysdot | CD31003034 | SGC707 98+% | 50mg | $375 | 2021-12-16 | Buy |
Crysdot | CD31003034 | SGC707 98+% | 100mg | $681 | 2021-12-16 | Buy |
Properties
storage temp. :-20°C
solubility :Soluble in DMSO (up to 35 mg/ml)
form :solid
color :Beige
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
solubility :Soluble in DMSO (up to 35 mg/ml)
form :solid
color :Beige
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Safety Information
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Signal word: | Warning | |||||||||||||||||||||||||||||||||||
Hazard statements: |
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Precautionary statements: |
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Description
Protein arginine N-methyltransferase 3 (PRMT3, ) is a predominantly cytoplasmic enzyme that is constitutively expressed. SGC707 is a potent allosteric inhibitor of PRMT3 (IC50 = 50 nM) with >100-fold selectivity over other methyltransferases and other non-epigenetic targets. Developed by the Structural Genomics Consortium (SGC), SGC707 avidly binds PRMT3 (Kd = 50 nM by isothermal titration calorimetry) and inhibits the methylation of histones in cells with an IC50 value below 1 μM.Related product price
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