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ChemicalBook >> CAS DataBase List >> Rosiglitazone

Rosiglitazone

Rosiglitazone price.
  • $12 - $970
  • Product name: Rosiglitazone
  • CAS: 122320-73-4
  • MF: C18H19N3O3S
  • MW: 357.43
  • EINECS:924-121-1
  • MDL Number:MFCD00871760
  • Synonyms:5-(4-[2-(METHYL-PYRIDIN-2-YL-AMINO)-ETHOXY]-BENZYL)-THIAZOLIDINE-2,4-DIONE;5-[[4-[2-(methyl-2-pyridinylamino)ethoxy]-phenyl]methyl]-2,4-thiazolidine-dione;ROSIGLITAZONE;Rosiglitazone free base ;Rosiglitazone and its intermediates;ROSIGLITAZONE 99%;RosiglitazoneBase/Hcl/Maleate;5-[4-[2-(N-Methyl-N-(2-pyridyl)amino)ethoxy]benzylidine]-2,4-thiazolidinedione
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  • Adipogen Life Sciences
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • AvaChem
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chemenu
  • Chem-Impex
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Matrix Scientific
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TCI Chemical
  • Tocris
  • TRC
  • Usbiological
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  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CR1-3570-M025
  • Product descriptionRosiglitazone ≥98%(HPLC)
  • Packaging25mg
  • Price$60
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ10213
  • Product descriptionRosiglitazone
  • Packaging250mg
  • Price$56
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA158185
  • Product description5-(4-(2-(Methyl(pyridin-2-yl)amino)ethoxy)benzyl)thiazolidine-2,4-dione 98+%
  • Packaging10mg
  • Price$12
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA158185
  • Product description5-(4-(2-(Methyl(pyridin-2-yl)amino)ethoxy)benzyl)thiazolidine-2,4-dione 98+%
  • Packaging50mg
  • Price$21
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA158185
  • Product description5-(4-(2-(Methyl(pyridin-2-yl)amino)ethoxy)benzyl)thiazolidine-2,4-dione 98+%
  • Packaging1g
  • Price$32
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA158185
  • Product description5-(4-(2-(Methyl(pyridin-2-yl)amino)ethoxy)benzyl)thiazolidine-2,4-dione 98+%
  • Packaging5g
  • Price$110
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA158185
  • Product description5-(4-(2-(Methyl(pyridin-2-yl)amino)ethoxy)benzyl)thiazolidine-2,4-dione 98+%
  • Packaging25g
  • Price$390
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0006964
  • Product descriptionRosiglitazone 95.00%
  • Packaging5MG
  • Price$424
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0006964
  • Product descriptionRosiglitazone 95.00%
  • Packaging100MG
  • Price$545
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0006964
  • Product descriptionRosiglitazone 95.00%
  • Packaging200MG
  • Price$668
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberA4304
  • Product descriptionRosiglitazone
  • Packaging25mg
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4304
  • Product descriptionRosiglitazone
  • Packaging10mM(in 1mL DMSO)
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4304
  • Product descriptionRosiglitazone
  • Packaging100mg
  • Price$70
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4304
  • Product descriptionRosiglitazone
  • Packaging200mg
  • Price$110
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS048499
  • Product descriptionRosiglitazone ≥98%
  • Packaging10mg
  • Price$12
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS048499
  • Product descriptionRosiglitazone ≥98%
  • Packaging50mg
  • Price$21
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Adipogen Life Sciences AG-CR1-3570-M025 Rosiglitazone ≥98%(HPLC) 25mg $60 2021-12-16 Buy
AK Scientific J10213 Rosiglitazone 250mg $56 2021-12-16 Buy
Ambeed A158185 5-(4-(2-(Methyl(pyridin-2-yl)amino)ethoxy)benzyl)thiazolidine-2,4-dione 98+% 10mg $12 2021-12-16 Buy
Ambeed A158185 5-(4-(2-(Methyl(pyridin-2-yl)amino)ethoxy)benzyl)thiazolidine-2,4-dione 98+% 50mg $21 2021-12-16 Buy
Ambeed A158185 5-(4-(2-(Methyl(pyridin-2-yl)amino)ethoxy)benzyl)thiazolidine-2,4-dione 98+% 1g $32 2021-12-16 Buy
Ambeed A158185 5-(4-(2-(Methyl(pyridin-2-yl)amino)ethoxy)benzyl)thiazolidine-2,4-dione 98+% 5g $110 2021-12-16 Buy
Ambeed A158185 5-(4-(2-(Methyl(pyridin-2-yl)amino)ethoxy)benzyl)thiazolidine-2,4-dione 98+% 25g $390 2021-12-16 Buy
American Custom Chemicals Corporation API0006964 Rosiglitazone 95.00% 5MG $424 2021-12-16 Buy
American Custom Chemicals Corporation API0006964 Rosiglitazone 95.00% 100MG $545 2021-12-16 Buy
American Custom Chemicals Corporation API0006964 Rosiglitazone 95.00% 200MG $668 2021-12-16 Buy
ApexBio Technology A4304 Rosiglitazone 25mg $50 2021-12-16 Buy
ApexBio Technology A4304 Rosiglitazone 10mM(in 1mL DMSO) $50 2021-12-16 Buy
ApexBio Technology A4304 Rosiglitazone 100mg $70 2021-12-16 Buy
ApexBio Technology A4304 Rosiglitazone 200mg $110 2021-12-16 Buy
Arctom AS048499 Rosiglitazone ≥98% 10mg $12 2021-12-16 Buy
Arctom AS048499 Rosiglitazone ≥98% 50mg $21 2021-12-16 Buy

Properties

Melting point :153-155 C
Boiling point :585.0±35.0 °C(Predicted)
Density :1.315±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: ≥10mg/mL
pka :6.34±0.50(Predicted)
form :powder
color :White to Off-White
Merck :14,8265
CAS DataBase Reference :122320-73-4(CAS DataBase Reference)
IARC :3 (Vol. 108) 2016

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H361 Suspected of damaging fertility or the unborn child Reproductive toxicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
H410 Very toxic to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 1 Warning GHS hazard pictograms P273, P391, P501
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P281 Use personal protective equipment as required.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P391 Collect spillage. Hazardous to the aquatic environment
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Rosiglitazone is a type of thiazolidinedione antidiabetics. Thiazolidinedione are agonists for peroxisome-proliferator–activated receptor γ (PPAR-γ). PPAR-γ receptors are ligand-activated nuclear transcription factors that modulate gene expression, lowering blood glucose primarily by increasing insulin sensitivity in peripheral tissues.
Rosiglitazone is widely used to lower blood glucose levels in patients with type 2 diabetes mellitus. Rosiglitazone functionalizes by makes the cells of the body more sensitive to the naturally produced insulin in body. It shouldn’t be used if the patient is injecting or inhaling insulin. Using rosiglitazone with insulin could increase the risk of heart failure. Patients having heart failure with symptoms or moderate to severe heart failure should not use Rosiglitazone.

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