OSI-420
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- $68 - $2728.69
- Product name: OSI-420
- CAS: 183321-86-0
- MF: C21H21N3O4
- MW: 379.41
- EINECS:
- MDL Number:MFCD09841129
- Synonyms:CP 373420;OSI-420 (free base);Erlotinib O-DesMethyl Metabolite;Erlotinib iMpurity H;Desmethyl Erlotinib (CP-473420, OSI-420);6-O-Desmethyl Erlotinib 1;2-((4-((3-ethynylphenyl)amino)-7-(2-methoxyethoxy)quinazolin-6-yl)oxy)ethan-1-ol;2-((4-((3-Ethynylphenyl)amino)-7-(2-methoxyethoxy)quinazolin-6-yl)oxy)ethanol
17 prices
Selected condition：
Brand
- American Custom Chemicals Corporation
- ApexBio Technology
- Biosynth Carbosynth
- Cayman Chemical
- ChemScene
- Crysdot
- TRC
Package
- 1MG
- 5mg
- 10MG
- 25mg
- 50mg
- 100mg
- 200mg
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberCHM0152394
- Product description2-(4-(3-ETHYNYLPHENYLAMINO)-7-(2-METHOXYETHOXY)QUINAZOLIN-6-YLOXY)ETHANOL 95.00%
- Packaging1MG
- Price$818.61
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberCHM0152394
- Product description2-(4-(3-ETHYNYLPHENYLAMINO)-7-(2-METHOXYETHOXY)QUINAZOLIN-6-YLOXY)ETHANOL 95.00%
- Packaging10MG
- Price$2728.69
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB1495
- Product descriptionOSI-420freebase
- Packaging200mg
- Price$2006
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFO26597
- Product descriptionDesmethyl erlotinib
- Packaging5mg
- Price$294
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFO26597
- Product descriptionDesmethyl erlotinib
- Packaging10mg
- Price$470
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFO26597
- Product descriptionDesmethyl erlotinib
- Packaging25mg
- Price$850
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFO26597
- Product descriptionDesmethyl erlotinib
- Packaging50mg
- Price$1350
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFO26597
- Product descriptionDesmethyl erlotinib
- Packaging100mg
- Price$1900
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number23394
- Product descriptionDesmethyl Erlotinib ≥98%
- Packaging1mg
- Price$68
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number23394
- Product descriptionDesmethyl Erlotinib ≥98%
- Packaging5mg
- Price$201
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number23394
- Product descriptionDesmethyl Erlotinib
- Packaging10mg
- Price$370
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-0003183
- Product descriptionDesmethylErlotinib 98.07%
- Packaging5mg
- Price$144
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0003183
- Product descriptionDesmethylErlotinib 98.07%
- Packaging10mg
- Price$252
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0003183
- Product descriptionDesmethylErlotinib 98.07%
- Packaging50mg
- Price$642
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD37000051
- Product description2-((4-((3-Ethynylphenyl)amino)-7-(2-methoxyethoxy)quinazolin-6-yl)oxy)ethanol 95+%
- Packaging5mg
- Price$221
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD37000051
- Product description2-((4-((3-Ethynylphenyl)amino)-7-(2-methoxyethoxy)quinazolin-6-yl)oxy)ethanol 95+%
- Packaging10mg
- Price$338
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| American Custom Chemicals Corporation | CHM0152394 | 2-(4-(3-ETHYNYLPHENYLAMINO)-7-(2-METHOXYETHOXY)QUINAZOLIN-6-YLOXY)ETHANOL 95.00% | 1MG | $818.61 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | CHM0152394 | 2-(4-(3-ETHYNYLPHENYLAMINO)-7-(2-METHOXYETHOXY)QUINAZOLIN-6-YLOXY)ETHANOL 95.00% | 10MG | $2728.69 | 2021-12-16 | Buy |
| ApexBio Technology | B1495 | OSI-420freebase | 200mg | $2006 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FO26597 | Desmethyl erlotinib | 5mg | $294 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FO26597 | Desmethyl erlotinib | 10mg | $470 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FO26597 | Desmethyl erlotinib | 25mg | $850 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FO26597 | Desmethyl erlotinib | 50mg | $1350 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FO26597 | Desmethyl erlotinib | 100mg | $1900 | 2021-12-16 | Buy |
| Cayman Chemical | 23394 | Desmethyl Erlotinib ≥98% | 1mg | $68 | 2024-03-01 | Buy |
| Cayman Chemical | 23394 | Desmethyl Erlotinib ≥98% | 5mg | $201 | 2024-03-01 | Buy |
| Cayman Chemical | 23394 | Desmethyl Erlotinib | 10mg | $370 | 2024-03-01 | Buy |
| ChemScene | CS-0003183 | DesmethylErlotinib 98.07% | 5mg | $144 | 2021-12-16 | Buy |
| ChemScene | CS-0003183 | DesmethylErlotinib 98.07% | 10mg | $252 | 2021-12-16 | Buy |
| ChemScene | CS-0003183 | DesmethylErlotinib 98.07% | 50mg | $642 | 2021-12-16 | Buy |
| Crysdot | CD37000051 | 2-((4-((3-Ethynylphenyl)amino)-7-(2-methoxyethoxy)quinazolin-6-yl)oxy)ethanol 95+% | 5mg | $221 | 2021-12-16 | Buy |
| Crysdot | CD37000051 | 2-((4-((3-Ethynylphenyl)amino)-7-(2-methoxyethoxy)quinazolin-6-yl)oxy)ethanol 95+% | 10mg | $338 | 2021-12-16 | Buy |
Properties
Melting point :140-142°C
Density :1.30
storage temp. :-20°C Freezer
solubility :insoluble in H2O; insoluble in EtOH; ≥51 mg/mL in DMSO
form :A crystalline solid
color :White to off-white
Density :1.30
storage temp. :-20°C Freezer
solubility :insoluble in H2O; insoluble in EtOH; ≥51 mg/mL in DMSO
form :A crystalline solid
color :White to off-white
Safety Information
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| Signal word: | Warning | ||||||||||||||
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Description
OSI-420 is a metabolite of Erlotinib. Erlontinib potently inhibits EGFR autophosphorylation in cultured human head and neck tumor cells, a cell line which exhibits high levels of EGFR. Erlotinib also inhibits the proliferation of PC-9 cell lines, which contain a deletion mutation on exon 19 of the EGFR gene. A combination of Erlotinib and rapamycin produced a synergistic inhibitory effect on cell growth.Related product price
- OSI-420-d4, Free Base (Desmethyl Erlotinib-d4)
$2905 - Dacomitinib (PF299804)
$28-1703 - CO-1686
$50-3510
