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ChemicalBook >> CAS DataBase List >> Nicorandil

Nicorandil

Nicorandil price.
  • $5 - $860
  • Product name: Nicorandil
  • CAS: 65141-46-0
  • MF: C8H9N3O4
  • MW: 211.17
  • EINECS:265-514-1
  • MDL Number:MFCD00186520
  • Synonyms:n-[2-(nitroxy)ethyl]-3-pyridinecarboxamide;N-[2-(NITROOXY)ETHYL]-3-PYRIDINECARBOXAMIDE;3-Pyridinecarboxamide, N-[2-(nitrooxy)ethyl]-;SG-75;Dancor;Nitric acid 2-nicotinoylaminoethyl ester;2-(pyridin-3-ylcarbonylamino)ethyl nitrate;2-(pyridine-3-carbonylamino)ethyl nitrate
46 prices
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  • AK Scientific
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  • y0001761
  • 10g
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  • 1g
  • 5g
  • 25g
  • 10mM(in 1mL DMSO)
  • ManufacturerAK Scientific
  • Product numberH924
  • Product descriptionNicorandil
  • Packaging25g
  • Price$187
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ60879
  • Product descriptionNicorandil, 98+%
  • Packaging250mg
  • Price$81.65
  • Updated2024-03-01
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ60879
  • Product descriptionNicorandil, 98+%
  • Packaging1g
  • Price$264.65
  • Updated2024-03-01
  • Buy
  • ManufacturerAmbeed
  • Product numberA957622
  • Product description2-(Nicotinamido)ethylnitrate 98%
  • Packaging50mg
  • Price$5
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA957622
  • Product description2-(Nicotinamido)ethylnitrate 98%
  • Packaging1g
  • Price$7
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA957622
  • Product description2-(Nicotinamido)ethylnitrate 98%
  • Packaging5g
  • Price$19
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA957622
  • Product description2-(Nicotinamido)ethylnitrate 98%
  • Packaging25g
  • Price$76
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB2197
  • Product descriptionNicorandil
  • Packaging50mg
  • Price$45
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB2197
  • Product descriptionNicorandil
  • Packaging10mM(in 1mL DMSO)
  • Price$50
  • Updated2021-12-16
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  • ManufacturerArctom
  • Product numberAS698962
  • Product descriptionNicorandil 98%
  • Packaging5g
  • Price$40
  • Updated2021-12-16
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  • ManufacturerArctom
  • Product numberAS698962
  • Product descriptionNicorandil 98%
  • Packaging25g
  • Price$130
  • Updated2021-12-16
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  • ManufacturerAronis compounds
  • Product numberBBC/474
  • Product description2-[(3-pyridinylcarbonyl)amino]ethylnitrate
  • Packaging1g
  • Price$122
  • Updated2021-12-16
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  • ManufacturerAronis compounds
  • Product numberBBC/474
  • Product description2-[(3-pyridinylcarbonyl)amino]ethylnitrate
  • Packaging10g
  • Price$524
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2828
  • Product descriptionNicorandil
  • Packaging10mg
  • Price$25
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2828
  • Product descriptionNicorandil
  • Packaging100mg
  • Price$45
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2828
  • Product descriptionNicorandil
  • Packaging250mg
  • Price$75
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific H924 Nicorandil 25g $187 2021-12-16 Buy
Alfa Aesar J60879 Nicorandil, 98+% 250mg $81.65 2024-03-01 Buy
Alfa Aesar J60879 Nicorandil, 98+% 1g $264.65 2024-03-01 Buy
Ambeed A957622 2-(Nicotinamido)ethylnitrate 98% 50mg $5 2021-12-16 Buy
Ambeed A957622 2-(Nicotinamido)ethylnitrate 98% 1g $7 2021-12-16 Buy
Ambeed A957622 2-(Nicotinamido)ethylnitrate 98% 5g $19 2021-12-16 Buy
Ambeed A957622 2-(Nicotinamido)ethylnitrate 98% 25g $76 2021-12-16 Buy
ApexBio Technology B2197 Nicorandil 50mg $45 2021-12-16 Buy
ApexBio Technology B2197 Nicorandil 10mM(in 1mL DMSO) $50 2021-12-16 Buy
Arctom AS698962 Nicorandil 98% 5g $40 2021-12-16 Buy
Arctom AS698962 Nicorandil 98% 25g $130 2021-12-16 Buy
Aronis compounds BBC/474 2-[(3-pyridinylcarbonyl)amino]ethylnitrate 1g $122 2021-12-16 Buy
Aronis compounds BBC/474 2-[(3-pyridinylcarbonyl)amino]ethylnitrate 10g $524 2021-12-16 Buy
AvaChem 2828 Nicorandil 10mg $25 2021-12-16 Buy
AvaChem 2828 Nicorandil 100mg $45 2021-12-16 Buy
AvaChem 2828 Nicorandil 250mg $75 2021-12-16 Buy

Properties

Melting point :92°C
Boiling point :350.85°C (rough estimate)
Density :1.4271 (rough estimate)
refractive index :1.7400 (estimate)
RTECS :US4667600
storage temp. :2-8°C
solubility :DMSO: >10mg/mL
pka :12.70±0.46(Predicted)
form :powder
color :white to off-white
Merck :14,6521
CAS DataBase Reference :65141-46-0

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H242 Heating may cause a fire Self-reactive substances and mixtures; and Organic peroxides Type C, D,Type E, F
Type G		 Danger
Warning		 GHS hazard pictograms P210, P220, P234, P280, P370+P378,P403+P235, P411, P420, P501
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P235 Keep cool.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P370+P378 In case of fire: Use … for extinction.
P410 Protect from sunlight.

Description

Nicorandil is a nicotinamide-nitric oxide ester with vasodilatory and cardioprotective effects. It is best known as a potassium channel activator that targets vascular nucleoside diphosphate-dependent K+ channels and cardiac ATP-sensitive K+ channels (EC50 = 10 μM). In addition to driving dilation of peripheral and coronary arterioles, K+ channel activation by nicorandil delays the induction of mitochondrial permeability transition in response to oxidative stress. Nicorandil can also act as a nitric oxide donor, increasing intracellular cGMP production leading to venodilation and pain suppression.

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