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ChemicalBook >> CAS DataBase List >> Ethyl 4-hydroxy-3-methoxycinnamate

Ethyl 4-hydroxy-3-methoxycinnamate

Ethyl 4-hydroxy-3-methoxycinnamate price.
  • $5 - $1116.89
  • Product name: Ethyl 4-hydroxy-3-methoxycinnamate
  • CAS: 4046-02-0
  • MF: C12H14O4
  • MW: 222.24
  • EINECS:223-745-5
  • MDL Number:MFCD00009190
  • Synonyms:ETHYL TRANS-3-(4'-HYDROXY-3'-METHOXYPHENYL)ACRYLATE;BUTTPARK 121\04-55;4-HYDROXY-3-METHOXYCINNAMIC ACID ETHYL ESTER;RARECHEM AL BI 0735;Ethyl ferulate~Ferulic acid ethyl ester~4-Hydroxy-3-methoxycinnamic acid ethyl ester;(E)-3-(4-HYDROXY-3-METHOXY-PHENYL)-ACRYLIC ACID ETHYL ESTER;Ferulic acid ethyl eser;ETHYL 4-HYDROXY-3-METHOXYCINNAMATE (FERULIC ACID ETHYL ESTER)
35 prices
Selected condition：
Brand
  • AHH
  • AK Scientific
  • Alfa Aesar
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Apolloscientific
  • Arctom
  • Biorbyt Ltd
  • Cayman Chemical
  • Chemenu
  • Crysdot
  • DC Chemicals
  • Frontier Specialty Chemicals
  • Matrix Scientific
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • SynQuest Laboratories
  • TCI Chemical
  • TRC
  • Usbiological
Package
  • 10mg
  • 100mg
  • 20mg
  • 10mM(in 1mL DMSO)
  • 250mg
  • 1g
  • 5g
  • 10g
  • 25g
  • 100g
  • 500g
  • 1000g
  • ManufacturerAHH
  • Product numberMT-12893
  • Product descriptionFerulicacidethylester 98%
  • Packaging100g
  • Price$418
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberM451
  • Product descriptionFerulicacidethylester
  • Packaging25g
  • Price$30
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberL14960
  • Product descriptionEthyl 4-hydroxy-3-methoxycinnamate, 99%
  • Packaging250mg
  • Price$26.65
  • Updated2024-03-01
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberL14960
  • Product descriptionEthyl 4-hydroxy-3-methoxycinnamate, 99%
  • Packaging1g
  • Price$66.65
  • Updated2024-03-01
  • Buy
  • ManufacturerAmbeed
  • Product numberA172065
  • Product descriptionEthylFerulate 98%
  • Packaging100mg
  • Price$5
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA172065
  • Product descriptionEthylFerulate 98%
  • Packaging5g
  • Price$9
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA172065
  • Product descriptionEthylFerulate 98%
  • Packaging10g
  • Price$13
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA172065
  • Product descriptionEthylFerulate 98%
  • Packaging25g
  • Price$26
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA172065
  • Product descriptionEthylFerulate 98%
  • Packaging100g
  • Price$96
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA172065
  • Product descriptionEthylFerulate 98%
  • Packaging500g
  • Price$274
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberING0004279
  • Product descriptionFERULIC ACID ETHYLESTER 95.00%
  • Packaging10G
  • Price$1116.89
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberN2444
  • Product descriptionEthylferulate
  • Packaging20mg
  • Price$40
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberN2444
  • Product descriptionEthylferulate
  • Packaging10mM(in 1mL DMSO)
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberOR24814
  • Product descriptionEthyl 4-hydroxy-3-methoxycinnamate 98%
  • Packaging25g
  • Price$35
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberSY019188
  • Product descriptionEthyl 4-hydroxy-3-methoxycinnamate ≥98%
  • Packaging10mg
  • Price$21.82
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb104519
  • Product descriptionEthyl 4'-hydroxy-3'-methoxycinnamate >98%,Standard References Grade
  • Packaging20mg
  • Price$569.5
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AHH MT-12893 Ferulicacidethylester 98% 100g $418 2021-12-16 Buy
AK Scientific M451 Ferulicacidethylester 25g $30 2021-12-16 Buy
Alfa Aesar L14960 Ethyl 4-hydroxy-3-methoxycinnamate, 99% 250mg $26.65 2024-03-01 Buy
Alfa Aesar L14960 Ethyl 4-hydroxy-3-methoxycinnamate, 99% 1g $66.65 2024-03-01 Buy
Ambeed A172065 EthylFerulate 98% 100mg $5 2021-12-16 Buy
Ambeed A172065 EthylFerulate 98% 5g $9 2021-12-16 Buy
Ambeed A172065 EthylFerulate 98% 10g $13 2021-12-16 Buy
Ambeed A172065 EthylFerulate 98% 25g $26 2021-12-16 Buy
Ambeed A172065 EthylFerulate 98% 100g $96 2021-12-16 Buy
Ambeed A172065 EthylFerulate 98% 500g $274 2021-12-16 Buy
American Custom Chemicals Corporation ING0004279 FERULIC ACID ETHYLESTER 95.00% 10G $1116.89 2021-12-16 Buy
ApexBio Technology N2444 Ethylferulate 20mg $40 2021-12-16 Buy
ApexBio Technology N2444 Ethylferulate 10mM(in 1mL DMSO) $50 2021-12-16 Buy
Apolloscientific OR24814 Ethyl 4-hydroxy-3-methoxycinnamate 98% 25g $35 2021-12-16 Buy
Arctom SY019188 Ethyl 4-hydroxy-3-methoxycinnamate ≥98% 10mg $21.82 2021-12-16 Buy
Biorbyt Ltd orb104519 Ethyl 4'-hydroxy-3'-methoxycinnamate >98%,Standard References Grade 20mg $569.5 2021-12-16 Buy

Properties

Melting point :63-65 °C(lit.)
Boiling point :164-166 °C0.5 mm Hg(lit.)
Density :1.0643 (rough estimate)
refractive index :1.4560 (estimate)
storage temp. :Sealed in dry,Room Temperature
solubility :Chloroform (Slightly), Ethyl Acetate (Slightly)
form :Solid
pka :8.88±0.18(Predicted)
color :White to Off-White
Sensitive :Light Sensitive
BRN :2696807
Stability :Hygroscopic, Light Sensitive
InChIKey :ATJVZXXHKSYELS-FNORWQNLSA-N
LogP :1.940 (est)
CAS DataBase Reference :4046-02-0(CAS DataBase Reference)
NIST Chemistry Reference :ethyl ferulate(4046-02-0)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Ferulic acid is a hydroxycinnamic acid that is abundant in plants and originally derived from giant fennel (F. communis). This naturally-occurring phenolic has antioxidant activities that provide protection against inflammation and cancer. Ferulic acid ethyl ester is a lipophilic derivative of ferulic acid, demonstrating increased ability to cross cell membranes. Ferulic acid ethyl ester has less antioxidant capacity than ferulic acid in neuronal PC12 cells (IC50 = 66.7 μM for ferulic acid ethyl ester vs. 44.6 μM for ferulic acid, 2,2-diphenyl-1-picrylhydrazyl radical scavenging). However, ferulic acid ethyl ester increases the expression of heme oxygenase-1, Hsp70, and Hsp72, providing neuroprotection against amyloid β-peptide. Moreover, ferulic acid ethyl ester (25 μM) completely prevents cytotoxicity induced by ultraviolet B irradiation of normal human epidermal melanocytes, again associated with an induced expression of heme oxygenase-1 and Hsp70.

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