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ChemicalBook >> CAS DataBase List >> Nafamostat mesylate

Nafamostat mesylate

Nafamostat mesylate price.
  • $13 - $1880
  • Product name: Nafamostat mesylate
  • CAS: 82956-11-4
  • MF: C21H25N5O8S2
  • MW: 539.58
  • EINECS:692-168-2
  • MDL Number:MFCD00941430
  • Synonyms:4-((aminoiminomethyl)amino)-benzoicaci6-(aminoiminomethyl)-2-naphthalenyl ;6-carbaMiMidoylnaphthalen-2-yl 4-guanidinobenzoate diMethanesulfonate;[amino-[6-[[4-(diaminomethyleneazaniumyl)phenyl]-oxomethoxy]-2-naphthyl]methylene]ammonium;[amino-[6-[4-(diaminomethyleneazaniumyl)benzoyl]oxy-2-naphthyl]methylene]ammonium;[amino-[6-[4-(diaminomethylideneazaniumyl)benzoyl]oxynaphthalen-2-yl]methylidene]azanium;[amino-[6-[4-(diaminomethylideneazaniumyl)phenyl]carbonyloxynaphthalen-2-yl]methylidene]azanium;Nafamostat mesylate, >=98%;5-methyl-1-{6-[(7-oxo-7h-furo[3,2-g]chromen-9-yl)oxy]hexyl}pyrimidine-2,4(1h,3h)-dione
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  • Adipogen Life Sciences
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Ark Pharm
  • AvaChem
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chem-Impex
  • ChemScene
  • Crysdot
  • CSNpharm
  • DC Chemicals
  • Matrix Scientific
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TCI Chemical
  • Tocris
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  • Usbiological
Package
  • 5mg
  • 10MG
  • 1unit
  • 50
  • 10
  • 20MG
  • 50mg
  • 100mg
  • 250mg
  • 500mg
  • 1g
  • 10g
  • 10mM(in 1mL H2O)
  • 5g
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CR1-3731-M050
  • Product descriptionNafamostat Mesylate ≥98%(HPLC)
  • Packaging50mg
  • Price$150
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberM731
  • Product descriptionNafamostat Mesylate
  • Packaging500mg
  • Price$537
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ55851
  • Product descriptionNafamostat Mesylate
  • Packaging1g
  • Price$644
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA570309
  • Product description6-Carbamimidoylnaphthalen-2-yl4-guanidinobenzoatedimethanesulfonate 98+%
  • Packaging5mg
  • Price$13
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA570309
  • Product description6-Carbamimidoylnaphthalen-2-yl4-guanidinobenzoatedimethanesulfonate 98+%
  • Packaging50mg
  • Price$31
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA570309
  • Product description6-Carbamimidoylnaphthalen-2-yl4-guanidinobenzoatedimethanesulfonate 98+%
  • Packaging100mg
  • Price$42
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA570309
  • Product description6-Carbamimidoylnaphthalen-2-yl4-guanidinobenzoatedimethanesulfonate 98+%
  • Packaging250mg
  • Price$61
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA570309
  • Product description6-Carbamimidoylnaphthalen-2-yl4-guanidinobenzoatedimethanesulfonate 98+%
  • Packaging5g
  • Price$462
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0003481
  • Product descriptionNAFAMOSTAT MESILATE 95.00%
  • Packaging10MG
  • Price$174.3
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0003481
  • Product descriptionNAFAMOSTAT MESILATE 95.00%
  • Packaging100MG
  • Price$1871.1
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA2586
  • Product descriptionNafamostatMesylate(FUT-175)
  • Packaging1unit
  • Price$28
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA2586
  • Product descriptionNafamostatMesylate(FUT-175)
  • Packaging10mg
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA2586
  • Product descriptionNafamostatMesylate(FUT-175)
  • Packaging10mM(in 1mL H2O)
  • Price$55
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA2586
  • Product descriptionNafamostatMesylate(FUT-175)
  • Packaging50mg
  • Price$150
  • Updated2021-12-16
  • Buy
  • ManufacturerArk Pharm
  • Product numberAK468861
  • Product descriptionNafamostat Mesylate 98+%
  • Packaging1g
  • Price$155
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2574
  • Product descriptionNafamostat Mesylate
  • Packaging10mg
  • Price$45
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Adipogen Life Sciences AG-CR1-3731-M050 Nafamostat Mesylate ≥98%(HPLC) 50mg $150 2021-12-16 Buy
AK Scientific M731 Nafamostat Mesylate 500mg $537 2021-12-16 Buy
AK Scientific J55851 Nafamostat Mesylate 1g $644 2021-12-16 Buy
Ambeed A570309 6-Carbamimidoylnaphthalen-2-yl4-guanidinobenzoatedimethanesulfonate 98+% 5mg $13 2021-12-16 Buy
Ambeed A570309 6-Carbamimidoylnaphthalen-2-yl4-guanidinobenzoatedimethanesulfonate 98+% 50mg $31 2021-12-16 Buy
Ambeed A570309 6-Carbamimidoylnaphthalen-2-yl4-guanidinobenzoatedimethanesulfonate 98+% 100mg $42 2021-12-16 Buy
Ambeed A570309 6-Carbamimidoylnaphthalen-2-yl4-guanidinobenzoatedimethanesulfonate 98+% 250mg $61 2021-12-16 Buy
Ambeed A570309 6-Carbamimidoylnaphthalen-2-yl4-guanidinobenzoatedimethanesulfonate 98+% 5g $462 2021-12-16 Buy
American Custom Chemicals Corporation API0003481 NAFAMOSTAT MESILATE 95.00% 10MG $174.3 2021-12-16 Buy
American Custom Chemicals Corporation API0003481 NAFAMOSTAT MESILATE 95.00% 100MG $1871.1 2021-12-16 Buy
ApexBio Technology A2586 NafamostatMesylate(FUT-175) 1unit $28 2021-12-16 Buy
ApexBio Technology A2586 NafamostatMesylate(FUT-175) 10mg $50 2021-12-16 Buy
ApexBio Technology A2586 NafamostatMesylate(FUT-175) 10mM(in 1mL H2O) $55 2021-12-16 Buy
ApexBio Technology A2586 NafamostatMesylate(FUT-175) 50mg $150 2021-12-16 Buy
Ark Pharm AK468861 Nafamostat Mesylate 98+% 1g $155 2021-12-16 Buy
AvaChem 2574 Nafamostat Mesylate 10mg $45 2021-12-16 Buy

Properties

Melting point :259-261°C
storage temp. :Sealed in dry,Room Temperature
solubility :Soluble in Water (up to 25 mg/ml).
form :powder
color :white to beige
Merck :14,6350
Stability :Stable for 2 years from date of purchase as supplied. Solutions in distilled water may be stored at 4°C for up to 1 month, or at -80°C for up to 6 months.
InChIKey :SRXKIZXIRHMPFW-UHFFFAOYSA-N
SMILES :CS(O)(=O)=O.CS(O)(=O)=O.C(OC1=CC=C2C(=C1)C=CC(C(=N)N)=C2)(=O)C1=CC=C(NC(N)=N)C=C1
CAS DataBase Reference :82956-11-4(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Nafamostat is a serine protease inhibitor that is capable of inhibiting trypsin (a digestive system protease; Ki = 15 nM), tryptase (a mast cell protease; Ki = 95.3 pM), and additional proteases in the coagulation cascade including thrombin (Ki = 0.84 μM). In a mouse model of allergic asthma, a dose of 300 mg/kg nafamostat mesylate has been shown to inhibit serine proteolytic activity, to decrease circulating levels of eosinophils and lymphocytes in bronchoalveolar lavage fluid, and to reduce interleukin-13 and eotaxin production associated with antigen-induced airway eosinophilia and goblet cell hyperplasia.

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