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ChemicalBook >> CAS DataBase List >> N4-Acetylcytidine

N4-Acetylcytidine

N4-Acetylcytidine price.
  • $5 - $796
  • Product name: N4-Acetylcytidine
  • CAS: 3768-18-1
  • MF: C11H15N3O6
  • MW: 285.25
  • EINECS:223-195-6
  • MDL Number:MFCD00006540
  • Synonyms:4-Acetyl-1-(beta-D-ribofuranosyl)cytosine;ACETYL CYTOSINE;N4-ACETYLCYTIDINE;4-Acetylcytidine;Acetamide, N-(1,2-dihydro-2-oxo-1-beta-D-ribofuranosyl-4-pyrimidinyl)-;n-acetyl-cytidin ;N-[1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-2-oxo-pyrimidin-4-yl]ethanamide;N-[1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-methylol-tetrahydrofuran-2-yl]-2-keto-pyrimidin-4-yl]acetamide
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  • AHH
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Ark Pharm
  • Biosynth Carbosynth
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  • ChemScene
  • Crysdot
  • Matrix Scientific
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  • Usbiological
Package
  • 250mg
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  • ManufacturerAHH
  • Product numberMT-56223
  • Product descriptionN4-Acetylcytidine 98%
  • Packaging10g
  • Price$710
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberE894
  • Product descriptionN4-Acetylcytidine
  • Packaging5g
  • Price$46
  • Updated2021-12-16
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  • ManufacturerAK Scientific
  • Product numberJ52781
  • Product descriptionN4-Acetylcytidine
  • Packaging25g
  • Price$100
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA270613
  • Product descriptionN-Acetylcytidine 97%
  • Packaging250mg
  • Price$6
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA270613
  • Product descriptionN-Acetylcytidine 97%
  • Packaging1g
  • Price$9
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA270613
  • Product descriptionN-Acetylcytidine 97%
  • Packaging5g
  • Price$27
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA270613
  • Product descriptionN-Acetylcytidine 97%
  • Packaging10g
  • Price$46
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA270613
  • Product descriptionN-Acetylcytidine 97%
  • Packaging25g
  • Price$98
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA270613
  • Product descriptionN-Acetylcytidine 97%
  • Packaging100g
  • Price$281
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberNUC0000683
  • Product descriptionACETYL CYTOSINE 95.00%
  • Packaging1G
  • Price$130.2
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberC6648
  • Product descriptionN4-Acetylcytidine
  • Packaging500mg
  • Price$50
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberC6648
  • Product descriptionN4-Acetylcytidine
  • Packaging1g
  • Price$85
  • Updated2021-12-16
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  • ManufacturerArk Pharm
  • Product numberP000182579
  • Product descriptionN-Acetylcytidine 97%
  • Packaging250mg
  • Price$5
  • Updated2021-12-16
  • Buy
  • ManufacturerArk Pharm
  • Product numberP000182579
  • Product descriptionN-Acetylcytidine 97%
  • Packaging1g
  • Price$9
  • Updated2021-12-16
  • Buy
  • ManufacturerArk Pharm
  • Product numberP000182579
  • Product descriptionN-Acetylcytidine 97%
  • Packaging5g
  • Price$29
  • Updated2021-12-16
  • Buy
  • ManufacturerArk Pharm
  • Product numberP000182579
  • Product descriptionN-Acetylcytidine 97%
  • Packaging10g
  • Price$49
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AHH MT-56223 N4-Acetylcytidine 98% 10g $710 2021-12-16 Buy
AK Scientific E894 N4-Acetylcytidine 5g $46 2021-12-16 Buy
AK Scientific J52781 N4-Acetylcytidine 25g $100 2021-12-16 Buy
Ambeed A270613 N-Acetylcytidine 97% 250mg $6 2021-12-16 Buy
Ambeed A270613 N-Acetylcytidine 97% 1g $9 2021-12-16 Buy
Ambeed A270613 N-Acetylcytidine 97% 5g $27 2021-12-16 Buy
Ambeed A270613 N-Acetylcytidine 97% 10g $46 2021-12-16 Buy
Ambeed A270613 N-Acetylcytidine 97% 25g $98 2021-12-16 Buy
Ambeed A270613 N-Acetylcytidine 97% 100g $281 2021-12-16 Buy
American Custom Chemicals Corporation NUC0000683 ACETYL CYTOSINE 95.00% 1G $130.2 2021-12-16 Buy
ApexBio Technology C6648 N4-Acetylcytidine 500mg $50 2021-12-16 Buy
ApexBio Technology C6648 N4-Acetylcytidine 1g $85 2021-12-16 Buy
Ark Pharm P000182579 N-Acetylcytidine 97% 250mg $5 2021-12-16 Buy
Ark Pharm P000182579 N-Acetylcytidine 97% 1g $9 2021-12-16 Buy
Ark Pharm P000182579 N-Acetylcytidine 97% 5g $29 2021-12-16 Buy
Ark Pharm P000182579 N-Acetylcytidine 97% 10g $49 2021-12-16 Buy

Properties

Melting point :199 °C (dec.)(lit.)
Density :1.72±0.1 g/cm3(Predicted)
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :DMSO (Slightly, Heated), Methanol (Slightly, Heated)
pka :10.21±0.20(Predicted)
form :Solid
color :White to Pale Yellow
PH :<1.5
λmax :247,297 (pH 7)
CAS DataBase Reference :3768-18-1(CAS DataBase Reference)
NIST Chemistry Reference :Cytidine, n-acetyl-(3768-18-1)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.

Description

N4-Acetylcytidine is a modified nucleoside and endogenous urinary nucleoside product of the degradation of tRNA. N4-Acetylcytidine is a biological marker for various cancers with elevated concentrations present in urine. tRNA has been shown to be excreted in abnormal amounts in the urine of cancer patients. tRNA from neoplastic tissue had a much more rapid turnover rate than the tRNA from the corresponding normal tissue. Evidence indicates that methylation of tRNA occurs only after synthesis of the intact macromolecule. Because there are no specific enzyme systems to incorporate the modified nucleosides into the macromolecular nucleic acid, these nucleosides once released in the process of tRNA turnover cannot be reutilized, nor are they further degraded, but are excreted in urine.
N4-Acetylcytidine is also a partially protected cytidine and therefore can be used as a synthetic building block to prepare further derivatized nucleosides such as 2’,3’-dideoxycytidine.

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