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ChemicalBook >> CAS DataBase List >> Maraviroc

Maraviroc

Maraviroc price.
  • $35 - $2245.7
  • Product name: Maraviroc
  • CAS: 376348-65-1
  • MF: C29H41F2N5O
  • MW: 513.68
  • EINECS:609-456-0
  • MDL Number:MFCD09953791
  • Synonyms:Maraviroc;Maraviroc(UK427857);4,4-Difluoro-N-[(1S)-3-[(1R,5S)-3-(3-methyl-5-propan-2-yl-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octan-8-yl]-1-phenylpropyl]cyclohexane-1-carboxamide;maroviroc;4,4-Difluoro-N-{(1S)-3-[3-(3-isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]oct-8-yl]-1-phenylpropyl}cyclohexanecarboxamide;Maraviroc(Selzentry);4,4-difluoro-N-[(1S)-3-[(1R,3R,5S)-3-[3-Methyl-5-(propan-2-yl)-4H-1,2,4-triazol-4-yl]-8-azabicyclo[3.2.1]octan-8-yl]-1-phenylpropyl]cyclohexane-1-carboxaMide;Celsentri
29 prices
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Brand
  • Activate Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • AvaChem
  • Biorbyt Ltd
  • Cayman Chemical
  • ChemScene
  • DC Chemicals
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • Tocris
  • TRC
Package
  • 10
  • 2.5mg
  • 20mg
  • 50mg
  • 5MG
  • 10MG
  • 25mg
  • 50
  • 250mg
  • 10mM(in 1mL DMSO)
  • 100mg
  • 1g
  • ManufacturerActivate Scientific
  • Product numberAS14745
  • Product descriptionMaraviroc 95+% ee
  • Packaging100mg
  • Price$281
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0003256
  • Product descriptionMARAVIROC 95.00%
  • Packaging5MG
  • Price$193.6
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0003256
  • Product descriptionMARAVIROC 95.00%
  • Packaging10MG
  • Price$762.3
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0003256
  • Product descriptionMARAVIROC 95.00%
  • Packaging100MG
  • Price$2055.9
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8311
  • Product descriptionMaraviroc
  • Packaging10mM(in 1mL DMSO)
  • Price$69
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberCFN60331
  • Product descriptionMaraviroc
  • Packaging20mg
  • Price$428
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2207
  • Product descriptionMaraviroc
  • Packaging5mg
  • Price$35
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2207
  • Product descriptionMaraviroc
  • Packaging10mg
  • Price$45
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2207
  • Product descriptionMaraviroc
  • Packaging25mg
  • Price$85
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2207
  • Product descriptionMaraviroc
  • Packaging100mg
  • Price$149
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2207
  • Product descriptionMaraviroc
  • Packaging1g
  • Price$585
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb154716
  • Product descriptionMaraviroc >98%
  • Packaging100mg
  • Price$615.4
  • Updated2021-12-16
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  • ManufacturerBiorbyt Ltd
  • Product numberorb154716
  • Product descriptionMaraviroc >98%
  • Packaging250mg
  • Price$1133.9
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb154716
  • Product descriptionMaraviroc >98%
  • Packaging1g
  • Price$2245.7
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number14641
  • Product descriptionMaraviroc ≥98%
  • Packaging5mg
  • Price$60
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number14641
  • Product descriptionMaraviroc ≥98%
  • Packaging10mg
  • Price$112
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Activate Scientific AS14745 Maraviroc 95+% ee 100mg $281 2021-12-16 Buy
American Custom Chemicals Corporation API0003256 MARAVIROC 95.00% 5MG $193.6 2021-12-16 Buy
American Custom Chemicals Corporation API0003256 MARAVIROC 95.00% 10MG $762.3 2021-12-16 Buy
American Custom Chemicals Corporation API0003256 MARAVIROC 95.00% 100MG $2055.9 2021-12-16 Buy
ApexBio Technology A8311 Maraviroc 10mM(in 1mL DMSO) $69 2021-12-16 Buy
Arctom CFN60331 Maraviroc 20mg $428 2021-12-16 Buy
AvaChem 2207 Maraviroc 5mg $35 2021-12-16 Buy
AvaChem 2207 Maraviroc 10mg $45 2021-12-16 Buy
AvaChem 2207 Maraviroc 25mg $85 2021-12-16 Buy
AvaChem 2207 Maraviroc 100mg $149 2021-12-16 Buy
AvaChem 2207 Maraviroc 1g $585 2021-12-16 Buy
Biorbyt Ltd orb154716 Maraviroc >98% 100mg $615.4 2021-12-16 Buy
Biorbyt Ltd orb154716 Maraviroc >98% 250mg $1133.9 2021-12-16 Buy
Biorbyt Ltd orb154716 Maraviroc >98% 1g $2245.7 2021-12-16 Buy
Cayman Chemical 14641 Maraviroc ≥98% 5mg $60 2024-03-01 Buy
Cayman Chemical 14641 Maraviroc ≥98% 10mg $112 2024-03-01 Buy

Properties

Melting point :79-81°C
Density :1.29±0.1 g/cm3(Predicted)
storage temp. :room temp
solubility :DMSO: >30mg/mL
pka :7.3(at 25℃)
form :white powder
color :White
optical activity :[α]-15/D
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
InChIKey :GSNHKUDZZFZSJB-RWJISDSDNA-N
SMILES :C(N1[C@@H]2CC[C@H]1C[C@H](N1C(=NN=C1C(C)C)C)C2)C[C@@H](C1C=CC=CC=1)NC(C1CCC(F)(F)CC1)=O |&1:2,5,7,19,r|
CAS DataBase Reference :376348-65-1(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Maraviroc is an antagonist of the C-C chemokine receptor type 5 (CCR5), inhibiting binding of the ligand RANTES with an IC50 value of 1.4 nM. Because human immunodeficiency virus (HIV) uses CCR5 to enter monocytes and macrophages, maraviroc inhibits HIV-1 replication in CCR5-expressing cells (IC50 = 2.8 nM). The pharmacokinetics of maraviroc in healthy male subjects have been delineated.

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