I-SAP
- $73 - $1097.25
- Product name: I-SAP
- CAS: 133538-58-6
- MF: C22H30INO4S
- MW: 531.45
- EINECS:
- MDL Number:MFCD00216083
- Synonyms:THROMBOXANE A2;I-SAP;IODOPHENYL SULFONYL AMINO PINANE;[3S-[1ALPHA,2ALPHA,3BETA-5ALPHA]]-7-[3-[[(4-IODOPHENYL)SULFONYL]AMINO]-6,6-DIMETHYLBICYCLO[3.1.1]HEPT-2-YL]-5Z-HEPTENOIC ACID;[3S-[1alpha,3beta-5alpha]]-7-[3-[[(4-Ifodophenyl)sulfonyl]amino]-6,6-dimethylbicyclo[3.1.1]hept-2-yl]-5Z-heptenoic acid;7-(6,6-dimethyl-3-(4-iodobenzenesulfonylamino)bicyclo(3.1.1.)hept-2-yl)-5-heptenoic acid;SZNMERGTFJHNSM-JAWYFFTGSA-N;I SAP,ISAP
6 prices
Selected condition:
Brand
- AHH
- AK Scientific
- American Custom Chemicals Corporation
- Cayman Chemical
Package
- 100μg
- 500μg
- 0.001g
- 1mg
- ManufacturerAHH
- Product numberMT-15685
- Product description[3S-[1alpha,3beta-5alpha]]-7-[3-[[(4-Ifodophenyl)sulfonyl]amino]6,6-dimethylbicyclo[3.1.1]hept-2-yl]-5Z-heptenoicacid 98%
- Packaging0.001g
- Price$298
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number1803AH
- Product descriptionI-SAP
- Packaging1mg
- Price$737
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberCHM0290099
- Product description[3S-[1ALPHA,3BETA-5ALPHA]]-7-[3-[[(4-IODOPHENYL)SULFONYL]AMINO]-6,6-DIMETHYLBICYCLO[3.1.1]HEPT-2-YL]-5Z-HEPTENOIC ACID 98.00%
- Packaging1MG
- Price$1097.25
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number19021
- Product descriptionI-SAP ≥98%
- Packaging100μg
- Price$73
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number19021
- Product descriptionI-SAP ≥98%
- Packaging500μg
- Price$324
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number19021
- Product descriptionI-SAP ≥98%
- Packaging1mg
- Price$575
- Updated2024-03-01
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AHH | MT-15685 | [3S-[1alpha,3beta-5alpha]]-7-[3-[[(4-Ifodophenyl)sulfonyl]amino]6,6-dimethylbicyclo[3.1.1]hept-2-yl]-5Z-heptenoicacid 98% | 0.001g | $298 | 2021-12-16 | Buy |
AK Scientific | 1803AH | I-SAP | 1mg | $737 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | CHM0290099 | [3S-[1ALPHA,3BETA-5ALPHA]]-7-[3-[[(4-IODOPHENYL)SULFONYL]AMINO]-6,6-DIMETHYLBICYCLO[3.1.1]HEPT-2-YL]-5Z-HEPTENOIC ACID 98.00% | 1MG | $1097.25 | 2021-12-16 | Buy |
Cayman Chemical | 19021 | I-SAP ≥98% | 100μg | $73 | 2024-03-01 | Buy |
Cayman Chemical | 19021 | I-SAP ≥98% | 500μg | $324 | 2024-03-01 | Buy |
Cayman Chemical | 19021 | I-SAP ≥98% | 1mg | $575 | 2024-03-01 | Buy |
Properties
Boiling point :606.3±61.0 °C(Predicted)
Density :1.51±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: >50 mg/ml (from Pinane TXA2); DMSO: >25 mg/ml (from Pinane TXA2); Ethanol: >100 mg/ml (from Pinane TXA2); PBS pH 7.2: >100 μg/ml (from Pinane TXA2)
pka :4.76±0.10(Predicted)
Density :1.51±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: >50 mg/ml (from Pinane TXA2); DMSO: >25 mg/ml (from Pinane TXA2); Ethanol: >100 mg/ml (from Pinane TXA2); PBS pH 7.2: >100 μg/ml (from Pinane TXA2)
pka :4.76±0.10(Predicted)
Safety Information
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Signal word: | Danger | ||||||||||||||||||||||||||||||
Hazard statements: |
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Precautionary statements: |
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Description
I-SAP is a high affinity TP receptor antagonist. At physiologic pH, I-SAP produces platelet shape change, but not aggregation, with an EC50 value of 9.7 nM. I-SAP binds to human platelets with the maximum binding obtained between pH 6.5 and pH 7.4. In washed human platelets, the Kd for I-SAP is 468 pM at pH 7.4 and 490 pM at pH 6.5.More related product prices
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