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ChemicalBook >> CAS DataBase List >> Harpagoside

Harpagoside

Harpagoside price.
  • $30 - $1680
  • Product name: Harpagoside
  • CAS: 19210-12-9
  • MF: C24H30O11
  • MW: 494.49
  • EINECS:242-881-6
  • MDL Number:MFCD00017415
  • Synonyms:HARPAGOSIDE;Harpagosid;[1S-[1alpha,4aalpha,5alpha,7alpha(E),7aalpha]]-1,4a,5,6,7,7a-hexahydro-4a,5-dihydroxy-7-methyl-7-[(allyl-1-oxo-3-phenyl)oxy]cyclopenta[c]pyran-1-yl-beta-D-glucopyranoside;[(1S,4aS,5R,7S,7aS)-4a,5-Dihydroxy-7-methyl-1-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-1,5,6,7a-tetrahydrocyclopenta[c]pyran-7-yl] (E)-3-phenylprop-2-enoate;HARPAGOSIDE WITH HPLC;7,7a-hexahydro-4a,5-dihydroxy-7-methyl-7-[[(2E)-1-oxo-3-phenyl-2-propen-1-yl]oxy]cyclopenta[c]pyran-1-yl;β-D-Glucopyranoside, (1S,4aS,5R,7S,7aS)-1,4a,5,6;8-O-E CINNAMOYL HARPAGIDE
49 prices
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Brand
  • AHH
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • AvaChem
  • Biorbyt Ltd
  • Biosynth Carbosynth
  • ChemScene
  • CSNpharm
  • DC Chemicals
  • JR MediChem
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TRC
  • Usbiological
Package
  • 20mg
  • 100mg
  • 250MG
  • 500mg
  • y0000673
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 1g
  • ManufacturerAHH
  • Product numberMT-52300
  • Product descriptionHarpagoside 98%
  • Packaging1g
  • Price$370
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberV0696
  • Product descriptionHarpagoside
  • Packaging5mg
  • Price$100
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberV0696
  • Product descriptionHarpagoside
  • Packaging10mg
  • Price$128
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberV0696
  • Product descriptionHarpagoside
  • Packaging25mg
  • Price$177
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberV0696
  • Product descriptionHarpagoside
  • Packaging1g
  • Price$1454
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA268491
  • Product descriptionHarpagoside 98%
  • Packaging5mg
  • Price$30
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA268491
  • Product descriptionHarpagoside 98%
  • Packaging10mg
  • Price$51
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA268491
  • Product descriptionHarpagoside 98%
  • Packaging25mg
  • Price$87
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA268491
  • Product descriptionHarpagoside 98%
  • Packaging50mg
  • Price$149
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA268491
  • Product descriptionHarpagoside 98%
  • Packaging1g
  • Price$1033
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0002891
  • Product descriptionHARPAGOSIDE 95.00%
  • Packaging5MG
  • Price$253
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0002891
  • Product descriptionHARPAGOSIDE 95.00%
  • Packaging250MG
  • Price$971.42
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberN1461
  • Product descriptionHarpagoside
  • Packaging20mg
  • Price$250
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS005991
  • Product descriptionHarpagoside 98%
  • Packaging5mg
  • Price$30
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS005991
  • Product descriptionHarpagoside 98%
  • Packaging10mg
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS005991
  • Product descriptionHarpagoside 98%
  • Packaging25mg
  • Price$86
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AHH MT-52300 Harpagoside 98% 1g $370 2021-12-16 Buy
AK Scientific V0696 Harpagoside 5mg $100 2021-12-16 Buy
AK Scientific V0696 Harpagoside 10mg $128 2021-12-16 Buy
AK Scientific V0696 Harpagoside 25mg $177 2021-12-16 Buy
AK Scientific V0696 Harpagoside 1g $1454 2021-12-16 Buy
Ambeed A268491 Harpagoside 98% 5mg $30 2021-12-16 Buy
Ambeed A268491 Harpagoside 98% 10mg $51 2021-12-16 Buy
Ambeed A268491 Harpagoside 98% 25mg $87 2021-12-16 Buy
Ambeed A268491 Harpagoside 98% 50mg $149 2021-12-16 Buy
Ambeed A268491 Harpagoside 98% 1g $1033 2021-12-16 Buy
American Custom Chemicals Corporation API0002891 HARPAGOSIDE 95.00% 5MG $253 2021-12-16 Buy
American Custom Chemicals Corporation API0002891 HARPAGOSIDE 95.00% 250MG $971.42 2021-12-16 Buy
ApexBio Technology N1461 Harpagoside 20mg $250 2021-12-16 Buy
Arctom AS005991 Harpagoside 98% 5mg $30 2021-12-16 Buy
Arctom AS005991 Harpagoside 98% 10mg $50 2021-12-16 Buy
Arctom AS005991 Harpagoside 98% 25mg $86 2021-12-16 Buy

Properties

Melting point :120°C (dec.)
Boiling point :720.7±60.0 °C(Predicted)
Density :1.52±0.1 g/cm3(Predicted)
storage temp. :Inert atmosphere,2-8°C
solubility :Aqueous Acid (Slightly), DMSO (Slightly), Methanol (Slightly)
pka :11.70±0.70(Predicted)
form :Solid
color :White to Light Yellow
Stability :Hygroscopic
InChIKey :KVRQGMOSZKPBNS-FMHLWDFHSA-N
LogP :-1.591 (est)
CAS DataBase Reference :19210-12-9(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:

Description

Harpagoside is an anti-inflammatory small molecule natural product originally isolated from the Harpagophytum procumbens (Devil’s Claw) root, but can be isolated from other plants such as Crophularia ningpoensis Hemsl (Figwort). Treatment of HepG2 cells with Harpagoside demonstrated suppression of NF-κB nuclear translocation and degradation of IκB-α, blocking NF-κB activation. Multiple anti-inflammatory cellular effects were correlated with this blockade, as Harpagoside was observed to inhibit the expression of inflammation-mediating enzymes cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase (iNOS), and to reduce lipopolysaccharide-induced mRNA levels. The suppression of NF-κB activation is indicated as the mechanism beneath the anti-inflammatory effects of Harpagoside.

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