Enzalutamide
- $5 - $17482.5
- Product name: Enzalutamide
- CAS: 915087-33-1
- MF: C21H16F4N4O2S
- MW: 464.44
- EINECS:805-022-1
- MDL Number:MFCD14155804
- Synonyms:4-{3-[4-cyano-3-(trifluoroMethyl)phenyl]-5,5-diMethyl-4-oxo-2-sulfanylideneiMidazolidin-1-yl}-2-fluoro-N-MethylbenzaMide;EnzalutaMide;MDV3100 (EnzalutaMide);ENZALUTAMIDE;MDV-3100;MDV-3100;4-[3-[4-Cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-thioxo-1-imidazolidinyl]-2-fluoro-N-methylbenzamide;4-(3-(4-Cyano-3-(trifluoromethyl)phenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl)-2-fluoro-N-methylbenzamide;MDV 3100,4-[3-[4-Cyano-3-(trifluoroMethyl)phenyl]-5,5-diMethyl-4-oxo-2-thioxo-1-iMidazolidinyl]-2-fluoro-N-MethylbenzaMide
45 prices
Selected condition:
Brand
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Biorbyt Ltd
- Biosynth Carbosynth
- Cayman Chemical
- Chemcia Scientific
- Chemenu
- DC Chemicals
- Matrix Scientific
- Medical Isotopes, Inc.
- TRC
- Usbiological
Package
- 1unit
- 10mM(in 1mL DMSO)
- 1mg
- 5mg
- 10mg
- 20mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1g
- 5g
- 10G
- 25g
- ManufacturerAK Scientific
- Product numberJ53619
- Product descriptionEnzalutamide
- Packaging25mg
- Price$94
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberW9480
- Product descriptionEnzalutamide
- Packaging100mg
- Price$261
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA270395
- Product description4-(3-(4-Cyano-3-(trifluoromethyl)phenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl)-2-fluoro-N-methylbenzamide 98+%
- Packaging1mg
- Price$5
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA270395
- Product description4-(3-(4-Cyano-3-(trifluoromethyl)phenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl)-2-fluoro-N-methylbenzamide 98+%
- Packaging5mg
- Price$7
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA270395
- Product description4-(3-(4-Cyano-3-(trifluoromethyl)phenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl)-2-fluoro-N-methylbenzamide 98+%
- Packaging10mg
- Price$9
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA270395
- Product description4-(3-(4-Cyano-3-(trifluoromethyl)phenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl)-2-fluoro-N-methylbenzamide 98+%
- Packaging25mg
- Price$12
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA270395
- Product description4-(3-(4-Cyano-3-(trifluoromethyl)phenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl)-2-fluoro-N-methylbenzamide 98+%
- Packaging50mg
- Price$15
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA270395
- Product description4-(3-(4-Cyano-3-(trifluoromethyl)phenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl)-2-fluoro-N-methylbenzamide 98+%
- Packaging100mg
- Price$20
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA270395
- Product description4-(3-(4-Cyano-3-(trifluoromethyl)phenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl)-2-fluoro-N-methylbenzamide 98+%
- Packaging250mg
- Price$29
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA270395
- Product description4-(3-(4-Cyano-3-(trifluoromethyl)phenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl)-2-fluoro-N-methylbenzamide 98+%
- Packaging1g
- Price$73
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA270395
- Product description4-(3-(4-Cyano-3-(trifluoromethyl)phenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl)-2-fluoro-N-methylbenzamide 98+%
- Packaging5g
- Price$251
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA270395
- Product description4-(3-(4-Cyano-3-(trifluoromethyl)phenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl)-2-fluoro-N-methylbenzamide 98+%
- Packaging25g
- Price$869
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0007596
- Product descriptionMDV 3100 95.00%
- Packaging1MG
- Price$650.52
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0007596
- Product descriptionMDV 3100 95.00%
- Packaging5G
- Price$3832.5
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0007596
- Product descriptionMDV 3100 95.00%
- Packaging10G
- Price$7245
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0007596
- Product descriptionMDV 3100 95.00%
- Packaging25G
- Price$17482.5
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AK Scientific | J53619 | Enzalutamide | 25mg | $94 | 2021-12-16 | Buy |
AK Scientific | W9480 | Enzalutamide | 100mg | $261 | 2021-12-16 | Buy |
Ambeed | A270395 | 4-(3-(4-Cyano-3-(trifluoromethyl)phenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl)-2-fluoro-N-methylbenzamide 98+% | 1mg | $5 | 2021-12-16 | Buy |
Ambeed | A270395 | 4-(3-(4-Cyano-3-(trifluoromethyl)phenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl)-2-fluoro-N-methylbenzamide 98+% | 5mg | $7 | 2021-12-16 | Buy |
Ambeed | A270395 | 4-(3-(4-Cyano-3-(trifluoromethyl)phenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl)-2-fluoro-N-methylbenzamide 98+% | 10mg | $9 | 2021-12-16 | Buy |
Ambeed | A270395 | 4-(3-(4-Cyano-3-(trifluoromethyl)phenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl)-2-fluoro-N-methylbenzamide 98+% | 25mg | $12 | 2021-12-16 | Buy |
Ambeed | A270395 | 4-(3-(4-Cyano-3-(trifluoromethyl)phenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl)-2-fluoro-N-methylbenzamide 98+% | 50mg | $15 | 2021-12-16 | Buy |
Ambeed | A270395 | 4-(3-(4-Cyano-3-(trifluoromethyl)phenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl)-2-fluoro-N-methylbenzamide 98+% | 100mg | $20 | 2021-12-16 | Buy |
Ambeed | A270395 | 4-(3-(4-Cyano-3-(trifluoromethyl)phenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl)-2-fluoro-N-methylbenzamide 98+% | 250mg | $29 | 2021-12-16 | Buy |
Ambeed | A270395 | 4-(3-(4-Cyano-3-(trifluoromethyl)phenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl)-2-fluoro-N-methylbenzamide 98+% | 1g | $73 | 2021-12-16 | Buy |
Ambeed | A270395 | 4-(3-(4-Cyano-3-(trifluoromethyl)phenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl)-2-fluoro-N-methylbenzamide 98+% | 5g | $251 | 2021-12-16 | Buy |
Ambeed | A270395 | 4-(3-(4-Cyano-3-(trifluoromethyl)phenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl)-2-fluoro-N-methylbenzamide 98+% | 25g | $869 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | API0007596 | MDV 3100 95.00% | 1MG | $650.52 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | API0007596 | MDV 3100 95.00% | 5G | $3832.5 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | API0007596 | MDV 3100 95.00% | 10G | $7245 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | API0007596 | MDV 3100 95.00% | 25G | $17482.5 | 2021-12-16 | Buy |
Properties
Melting point :198 - 200°C
Density :1.49
storage temp. :-20°C
solubility :Soluble in DMSO (>25 mg/ml)
form :solid
pka :13.88±0.46(Predicted)
color :White to off-white
Stability :Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
InChI :InChI=1S/C21H16F4N4O2S/c1-20(2)18(31)28(12-5-4-11(10-26)15(8-12)21(23,24)25)19(32)29(20)13-6-7-14(16(22)9-13)17(30)27-3/h4-9H,1-3H3,(H,27,30)
InChIKey :WXCXUHSOUPDCQV-UHFFFAOYSA-N
SMILES :C(NC)(=O)C1=CC=C(N2C(=S)N(C3=CC=C(C#N)C(C(F)(F)F)=C3)C(=O)C2(C)C)C=C1F
Density :1.49
storage temp. :-20°C
solubility :Soluble in DMSO (>25 mg/ml)
form :solid
pka :13.88±0.46(Predicted)
color :White to off-white
Stability :Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
InChI :InChI=1S/C21H16F4N4O2S/c1-20(2)18(31)28(12-5-4-11(10-26)15(8-12)21(23,24)25)19(32)29(20)13-6-7-14(16(22)9-13)17(30)27-3/h4-9H,1-3H3,(H,27,30)
InChIKey :WXCXUHSOUPDCQV-UHFFFAOYSA-N
SMILES :C(NC)(=O)C1=CC=C(N2C(=S)N(C3=CC=C(C#N)C(C(F)(F)F)=C3)C(=O)C2(C)C)C=C1F
Safety Information
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Signal word: | Warning | ||||||||||||||||||||||||||||
Hazard statements: |
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Precautionary statements: |
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Description
MDV 3100 is a non-steroidal androgen receptor antagonist (IC50 = 36 nM). It reduces the efficiency of nuclear translocation of the androgen receptor and impairs both its binding to DNA and the recruitment of coactivators. It is orally available and induces tumor regression in mouse models of castration-resistant human prostate cancer. It has applications in advanced cancers that remain dependent on androgen receptor signaling even in the absence of androgen.More related product prices
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