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ChemicalBook >> CAS DataBase List >> EA4

EA4

EA4 price.
  • $90 - $1416
  • Product name: EA4
  • CAS: 389614-94-2
  • MF: C19H17ClN2O2
  • MW: 340.8
  • EINECS:
  • MDL Number:MFCD08457916
  • Synonyms:EA4;7-chloro-6-[4-(diethylamino)phenyl]quinoline-5,8-dione;5,8-Quinolinedione, 7-chloro-6-[4-(diethylamino)phenyl]-
12 prices
Selected condition：
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Cayman Chemical
  • Sigma-Aldrich
Package
  • 96073116-DNA-5UG
  • 5mg
  • 10mg
  • 50mg
  • 100mg
  • 1VIAL
  • ManufacturerAK Scientific
  • Product number5153CR
  • Product description7-Chloro-6-[4-(diethylamino)phenyl]quinoline-5,8-dione
  • Packaging5mg
  • Price$198
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0002620
  • Product description7-CHLORO-6-[4-(DIETHYLAMINO)PHENYL]-5,8-QUINOLINEDIONE 95.00%
  • Packaging5MG
  • Price$503.42
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC5169
  • Product descriptionEA4
  • Packaging5mg
  • Price$102
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC5169
  • Product descriptionEA4
  • Packaging10mg
  • Price$193
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC5169
  • Product descriptionEA4
  • Packaging50mg
  • Price$810
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC5169
  • Product descriptionEA4
  • Packaging100mg
  • Price$1416
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number10111
  • Product descriptionEA4 ≥95%
  • Packaging5mg
  • Price$90
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10111
  • Product descriptionEA4 ≥95%
  • Packaging10mg
  • Price$171
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10111
  • Product descriptionEA4 ≥95%
  • Packaging50mg
  • Price$710
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10111
  • Product descriptionEA4 ≥95%
  • Packaging100mg
  • Price$1241
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberCB_96073116
  • Product descriptionEa.4 96073116
  • Packaging1VIAL
  • Price$951
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberCB_96073116
  • Product descriptionEa.4 96073116
  • Packaging96073116-DNA-5UG
  • Price$390
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 5153CR 7-Chloro-6-[4-(diethylamino)phenyl]quinoline-5,8-dione 5mg $198 2021-12-16 Buy
American Custom Chemicals Corporation INB0002620 7-CHLORO-6-[4-(DIETHYLAMINO)PHENYL]-5,8-QUINOLINEDIONE 95.00% 5MG $503.42 2021-12-16 Buy
ApexBio Technology C5169 EA4 5mg $102 2021-12-16 Buy
ApexBio Technology C5169 EA4 10mg $193 2021-12-16 Buy
ApexBio Technology C5169 EA4 50mg $810 2021-12-16 Buy
ApexBio Technology C5169 EA4 100mg $1416 2021-12-16 Buy
Cayman Chemical 10111 EA4 ≥95% 5mg $90 2024-03-01 Buy
Cayman Chemical 10111 EA4 ≥95% 10mg $171 2024-03-01 Buy
Cayman Chemical 10111 EA4 ≥95% 50mg $710 2024-03-01 Buy
Cayman Chemical 10111 EA4 ≥95% 100mg $1241 2024-03-01 Buy
Sigma-Aldrich CB_96073116 Ea.4 96073116 1VIAL $951 2024-03-01 Buy
Sigma-Aldrich CB_96073116 Ea.4 96073116 96073116-DNA-5UG $390 2024-03-01 Buy

Properties

Boiling point :508.3±50.0 °C(Predicted)
Density :1.31±0.1 g/cm3(Predicted)
storage temp. :-196°C
solubility :≤1mg/ml in DMSO;20mg/ml in dimethyl formamide
form :crystalline solid
pka :6.14±0.44(Predicted)
color :Light blue to blue

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

rPLA2 is a calcium-dependent cytosolic phospholipase A2 (cPLA2) initially isolated and characterized from bovine and human red blood cells (RBCs). It has a molecular mass of 42 kDa and biochemical properties similar to cPLA2 Type IV. EA4 is a quinone derivative that inhibits rPLA2 with a Ki of 130 μM. It inhibits the ionophore-induced arachidonic acid release from human and bovine red blood cells (RBCs), indicating that rPLA2 is responsible for the Ca2+-dependent release of arachidonic acid from mammalian RBCs. EA4 causes significant time- and concentration-dependent induction of cytochrome P450 1A1 (CYP1A1) mRNA and protein in murine hepatoma Hepa-1c1c7 cells. EA4 also modulates CYP1A1 and CYP1B1 expression in other cell lines such as MCF-7, Hep-G2, and HL-60.

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