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ChemicalBook >> CAS DataBase List >> Diosmetin

Diosmetin

Diosmetin price.
  • $5 - $770
  • Product name: Diosmetin
  • CAS: 520-34-3
  • MF: C16H12O6
  • MW: 300.26
  • EINECS:208-291-8
  • MDL Number:MFCD00017425
  • Synonyms:3',5,7-TRIHYDROXY-4'METHOXYFLAVONE;4'-METHOXY-5,7,3'-TRIHYDROXYFLAVONE;4-METHOXY-5,7,3'-TRIHYDROXYFLAVONE;5,7,3'-TRIHYDROXY-4'-METHOXYFLAVONE;DIOSMETIN;5,7-Dihydroxy-2-[3-hydroxy-4-methoxyphenyl]-[4H]-1-benzopyran-4-one;4'-Methylluteolin;Diosmetol
48 prices
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  • AHH
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • AvaChem
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  • Biosynth Carbosynth
  • Cayman Chemical
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  • 10mM(in 1mL DMSO)
  • ManufacturerAHH
  • Product numberAPI-1501
  • Product descriptionDiosmetin 98%
  • Packaging25g
  • Price$750
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ51310
  • Product descriptionDiosmetin
  • Packaging1g
  • Price$117
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA124051
  • Product descriptionDiosmetin 96%
  • Packaging5g
  • Price$32
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA124051
  • Product descriptionDiosmetin 96%
  • Packaging10g
  • Price$53
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA124051
  • Product descriptionDiosmetin 96%
  • Packaging25g
  • Price$104
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberPXT0005231
  • Product descriptionDIOSMETIN 95.00%
  • Packaging100MG
  • Price$202.65
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB5990
  • Product descriptionDiosmetin
  • Packaging10mM(in 1mL DMSO)
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS014529
  • Product descriptionDiosmetin 96%
  • Packaging100mg
  • Price$5
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS014529
  • Product descriptionDiosmetin 96%
  • Packaging250mg
  • Price$8
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS014529
  • Product descriptionDiosmetin 96%
  • Packaging1g
  • Price$13
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS014529
  • Product descriptionDiosmetin 96%
  • Packaging5g
  • Price$32
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberCFN90210
  • Product descriptionDiosmetin ≥98%
  • Packaging20mg
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS014529
  • Product descriptionDiosmetin 96%
  • Packaging10g
  • Price$52
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS014529
  • Product descriptionDiosmetin 96%
  • Packaging25g
  • Price$103
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberSY066981
  • Product description5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-chromen-4-one ≥95%
  • Packaging100g
  • Price$270
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2729
  • Product descriptionDiosmetin
  • Packaging10mg
  • Price$39
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AHH API-1501 Diosmetin 98% 25g $750 2021-12-16 Buy
AK Scientific J51310 Diosmetin 1g $117 2021-12-16 Buy
Ambeed A124051 Diosmetin 96% 5g $32 2021-12-16 Buy
Ambeed A124051 Diosmetin 96% 10g $53 2021-12-16 Buy
Ambeed A124051 Diosmetin 96% 25g $104 2021-12-16 Buy
American Custom Chemicals Corporation PXT0005231 DIOSMETIN 95.00% 100MG $202.65 2021-12-16 Buy
ApexBio Technology B5990 Diosmetin 10mM(in 1mL DMSO) $50 2021-12-16 Buy
Arctom AS014529 Diosmetin 96% 100mg $5 2021-12-16 Buy
Arctom AS014529 Diosmetin 96% 250mg $8 2021-12-16 Buy
Arctom AS014529 Diosmetin 96% 1g $13 2021-12-16 Buy
Arctom AS014529 Diosmetin 96% 5g $32 2021-12-16 Buy
Arctom CFN90210 Diosmetin ≥98% 20mg $50 2021-12-16 Buy
Arctom AS014529 Diosmetin 96% 10g $52 2021-12-16 Buy
Arctom AS014529 Diosmetin 96% 25g $103 2021-12-16 Buy
Arctom SY066981 5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-chromen-4-one ≥95% 100g $270 2021-12-16 Buy
AvaChem 2729 Diosmetin 10mg $39 2021-12-16 Buy

Properties

Melting point :256-258°C
Boiling point :576.7±50.0 °C(Predicted)
Density :1.512±0.06 g/cm3(Predicted)
vapor pressure :0Pa at 20℃
storage temp. :Sealed in dry,2-8°C
solubility :Soluble in acetonitrile, DMSO (60 mg/ml), and ethanol (17 mg/ml), clear, light yellow to yellow.
form :Solid
pka :6.50±0.40(Predicted)
color :light yellow to yellow
Water Solubility :19μg/L at 20℃
BRN :294492
Stability :Hygroscopic
InChIKey :MBNGWHIJMBWFHU-UHFFFAOYSA-N
LogP :3.1 at 20℃
CAS DataBase Reference :520-34-3(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Diosmetin is a natural O-methylated flavone that is structurally related to luteolin . It reversibly inhibits cytochrome P450 (CYP) isoforms 1A1 and 1B1 in human liver microsomes with Ki values of 89 and 16 nM, respectively. It less potently inhibits CYP2C8 and CYP2C9 (Kis = 3.1 and 1.7 μM, respectively). While diosmetin inhibits CYP1A1 activity, it increases the transcription of the CYP1A1 gene in MCF-7 cells by activating the aryl hydrocarbon receptor when applied at 5 μM. Diosmetin also inhibits signaling through the stem cell factor receptor, c-Kit, at micromolar concentrations.

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