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ChemicalBook >> CAS DataBase List >> Cereblon Ligand 1

Cereblon Ligand 1

Cereblon Ligand 1 price.
  • $10 - $1600
  • Product name: Cereblon Ligand 1
  • CAS: 1061605-21-7
  • MF: C15H12N2O7
  • MW: 332.27
  • EINECS:
  • MDL Number:MFCD31560477
  • Synonyms:Cereblon Ligand 1;2-[[2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]acetic acid;Cereblon ligand 3;Pomalidomide Related Compound 1;Thalidomide-Acid;Acetic acid, 2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]-;2-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]oxyacetic acid;Thalidomide-4-hydroxyacetate
14 prices
Selected condition:
Brand
  • A1 Biochem Labs
  • Ambeed
  • BroadPharm
  • Cayman Chemical
  • Chemenu
  • DC Chemicals
  • Tocris
Package
  • 100
  • 1mg
  • 10mg
  • 100mg
  • 250mg
  • 500mg
  • 1g
  • ManufacturerA1 Biochem Labs
  • Product number6590504
  • Product description2-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)aceticacid 95%
  • Packaging250mg
  • Price$450
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA511927
  • Product description2-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)aceticacid 95%
  • Packaging1mg
  • Price$10
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA511927
  • Product description2-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)aceticacid 95%
  • Packaging100mg
  • Price$99
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA511927
  • Product description2-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)aceticacid 95%
  • Packaging250mg
  • Price$149
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA511927
  • Product description2-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)aceticacid 95%
  • Packaging1g
  • Price$370
  • Updated2021-12-16
  • Buy
  • ManufacturerBroadPharm
  • Product numberBP-24447
  • Product descriptionThalidomide-Acid 98%
  • Packaging250mg
  • Price$540
  • Updated2021-12-16
  • Buy
  • ManufacturerBroadPharm
  • Product numberBP-24447
  • Product descriptionThalidomide-Acid 98%
  • Packaging500mg
  • Price$890
  • Updated2021-12-16
  • Buy
  • ManufacturerBroadPharm
  • Product numberBP-24447
  • Product descriptionThalidomide-Acid 98%
  • Packaging1g
  • Price$1600
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number21589
  • Product descriptionCereblon Ligand 1 ≥98%
  • Packaging10mg
  • Price$81
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number21589
  • Product descriptionCereblon Ligand 1 ≥98%
  • Packaging100mg
  • Price$475
  • Updated2024-03-01
  • Buy
  • ManufacturerChemenu
  • Product numberCM327251
  • Product description2-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]oxyaceticacid 95%+
  • Packaging500mg
  • Price$294
  • Updated2021-12-16
  • Buy
  • ManufacturerChemenu
  • Product numberCM327251
  • Product description2-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]oxyaceticacid 95%+
  • Packaging1g
  • Price$460
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC11571
  • Product descriptionE3LigaseLigand3 >98%
  • Packaging1g
  • Price$700
  • Updated2021-12-16
  • Buy
  • ManufacturerTocris
  • Product number6466
  • Product descriptionTCE35031 ≥98%(HPLC)
  • Packaging100
  • Price$439
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
A1 Biochem Labs 6590504 2-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)aceticacid 95% 250mg $450 2021-12-16 Buy
Ambeed A511927 2-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)aceticacid 95% 1mg $10 2021-12-16 Buy
Ambeed A511927 2-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)aceticacid 95% 100mg $99 2021-12-16 Buy
Ambeed A511927 2-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)aceticacid 95% 250mg $149 2021-12-16 Buy
Ambeed A511927 2-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)aceticacid 95% 1g $370 2021-12-16 Buy
BroadPharm BP-24447 Thalidomide-Acid 98% 250mg $540 2021-12-16 Buy
BroadPharm BP-24447 Thalidomide-Acid 98% 500mg $890 2021-12-16 Buy
BroadPharm BP-24447 Thalidomide-Acid 98% 1g $1600 2021-12-16 Buy
Cayman Chemical 21589 Cereblon Ligand 1 ≥98% 10mg $81 2024-03-01 Buy
Cayman Chemical 21589 Cereblon Ligand 1 ≥98% 100mg $475 2024-03-01 Buy
Chemenu CM327251 2-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]oxyaceticacid 95%+ 500mg $294 2021-12-16 Buy
Chemenu CM327251 2-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]oxyaceticacid 95%+ 1g $460 2021-12-16 Buy
DC Chemicals DC11571 E3LigaseLigand3 >98% 1g $700 2021-12-16 Buy
Tocris 6466 TCE35031 ≥98%(HPLC) 100 $439 2021-12-16 Buy

Properties

Boiling point :660.5±55.0 °C(Predicted)
Density :1.606±0.06 g/cm3(Predicted)
solubility :Soluble in DCM
form :A crystalline solid
pka :2.95±0.10(Predicted)
color :White to off-white
InChI :InChI=1S/C15H12N2O7/c18-10-5-4-8(13(21)16-10)17-14(22)7-2-1-3-9(12(7)15(17)23)24-6-11(19)20/h1-3,8H,4-6H2,(H,19,20)(H,16,18,21)
InChIKey :ZVWIXIGBWIEDFO-UHFFFAOYSA-N
SMILES :C(O)(=O)COC1=CC=CC2=C1C(=O)N(C1CCC(=O)NC1=O)C2=O

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Thalidomide-Acid (Cereblon Ligand 1) is a linker of Thalidomide which is commonly used as a precursor to PROTAC that hijacks cereblon as the E3 ubiquitin ligase component.