Cereblon Ligand 1
- $10 - $1600
- Product name: Cereblon Ligand 1
- CAS: 1061605-21-7
- MF: C15H12N2O7
- MW: 332.27
- EINECS:
- MDL Number:MFCD31560477
- Synonyms:Cereblon Ligand 1;2-[[2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]acetic acid;Cereblon ligand 3;Pomalidomide Related Compound 1;Thalidomide-Acid;Acetic acid, 2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]-;2-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]oxyacetic acid;Thalidomide-4-hydroxyacetate
14 prices
Selected condition:
Brand
- A1 Biochem Labs
- Ambeed
- BroadPharm
- Cayman Chemical
- Chemenu
- DC Chemicals
- Tocris
Package
- 100
- 1mg
- 10mg
- 100mg
- 250mg
- 500mg
- 1g
- ManufacturerA1 Biochem Labs
- Product number6590504
- Product description2-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)aceticacid 95%
- Packaging250mg
- Price$450
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA511927
- Product description2-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)aceticacid 95%
- Packaging1mg
- Price$10
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA511927
- Product description2-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)aceticacid 95%
- Packaging100mg
- Price$99
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA511927
- Product description2-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)aceticacid 95%
- Packaging250mg
- Price$149
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA511927
- Product description2-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)aceticacid 95%
- Packaging1g
- Price$370
- Updated2021-12-16
- Buy
- ManufacturerBroadPharm
- Product numberBP-24447
- Product descriptionThalidomide-Acid 98%
- Packaging250mg
- Price$540
- Updated2021-12-16
- Buy
- ManufacturerBroadPharm
- Product numberBP-24447
- Product descriptionThalidomide-Acid 98%
- Packaging500mg
- Price$890
- Updated2021-12-16
- Buy
- ManufacturerBroadPharm
- Product numberBP-24447
- Product descriptionThalidomide-Acid 98%
- Packaging1g
- Price$1600
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number21589
- Product descriptionCereblon Ligand 1 ≥98%
- Packaging10mg
- Price$81
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number21589
- Product descriptionCereblon Ligand 1 ≥98%
- Packaging100mg
- Price$475
- Updated2024-03-01
- Buy
- ManufacturerChemenu
- Product numberCM327251
- Product description2-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]oxyaceticacid 95%+
- Packaging500mg
- Price$294
- Updated2021-12-16
- Buy
- ManufacturerChemenu
- Product numberCM327251
- Product description2-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]oxyaceticacid 95%+
- Packaging1g
- Price$460
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC11571
- Product descriptionE3LigaseLigand3 >98%
- Packaging1g
- Price$700
- Updated2021-12-16
- Buy
- ManufacturerTocris
- Product number6466
- Product descriptionTCE35031 ≥98%(HPLC)
- Packaging100
- Price$439
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
A1 Biochem Labs | 6590504 | 2-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)aceticacid 95% | 250mg | $450 | 2021-12-16 | Buy |
Ambeed | A511927 | 2-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)aceticacid 95% | 1mg | $10 | 2021-12-16 | Buy |
Ambeed | A511927 | 2-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)aceticacid 95% | 100mg | $99 | 2021-12-16 | Buy |
Ambeed | A511927 | 2-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)aceticacid 95% | 250mg | $149 | 2021-12-16 | Buy |
Ambeed | A511927 | 2-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)aceticacid 95% | 1g | $370 | 2021-12-16 | Buy |
BroadPharm | BP-24447 | Thalidomide-Acid 98% | 250mg | $540 | 2021-12-16 | Buy |
BroadPharm | BP-24447 | Thalidomide-Acid 98% | 500mg | $890 | 2021-12-16 | Buy |
BroadPharm | BP-24447 | Thalidomide-Acid 98% | 1g | $1600 | 2021-12-16 | Buy |
Cayman Chemical | 21589 | Cereblon Ligand 1 ≥98% | 10mg | $81 | 2024-03-01 | Buy |
Cayman Chemical | 21589 | Cereblon Ligand 1 ≥98% | 100mg | $475 | 2024-03-01 | Buy |
Chemenu | CM327251 | 2-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]oxyaceticacid 95%+ | 500mg | $294 | 2021-12-16 | Buy |
Chemenu | CM327251 | 2-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]oxyaceticacid 95%+ | 1g | $460 | 2021-12-16 | Buy |
DC Chemicals | DC11571 | E3LigaseLigand3 >98% | 1g | $700 | 2021-12-16 | Buy |
Tocris | 6466 | TCE35031 ≥98%(HPLC) | 100 | $439 | 2021-12-16 | Buy |
Properties
Boiling point :660.5±55.0 °C(Predicted)
Density :1.606±0.06 g/cm3(Predicted)
solubility :Soluble in DCM
form :A crystalline solid
pka :2.95±0.10(Predicted)
color :White to off-white
InChI :InChI=1S/C15H12N2O7/c18-10-5-4-8(13(21)16-10)17-14(22)7-2-1-3-9(12(7)15(17)23)24-6-11(19)20/h1-3,8H,4-6H2,(H,19,20)(H,16,18,21)
InChIKey :ZVWIXIGBWIEDFO-UHFFFAOYSA-N
SMILES :C(O)(=O)COC1=CC=CC2=C1C(=O)N(C1CCC(=O)NC1=O)C2=O
Density :1.606±0.06 g/cm3(Predicted)
solubility :Soluble in DCM
form :A crystalline solid
pka :2.95±0.10(Predicted)
color :White to off-white
InChI :InChI=1S/C15H12N2O7/c18-10-5-4-8(13(21)16-10)17-14(22)7-2-1-3-9(12(7)15(17)23)24-6-11(19)20/h1-3,8H,4-6H2,(H,19,20)(H,16,18,21)
InChIKey :ZVWIXIGBWIEDFO-UHFFFAOYSA-N
SMILES :C(O)(=O)COC1=CC=CC2=C1C(=O)N(C1CCC(=O)NC1=O)C2=O
Safety Information
Symbol(GHS): | ||||||||||||||||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Signal word: | Warning | |||||||||||||||||||||||||||||||||||
Hazard statements: |
|
|||||||||||||||||||||||||||||||||||
Precautionary statements: |
|
Description
Thalidomide-Acid (Cereblon Ligand 1) is a linker of Thalidomide which is commonly used as a precursor to PROTAC that hijacks cereblon as the E3 ubiquitin ligase component.More related product prices
2-(2,6-dioxopiperidin-3-yl)-4-fluoroisoindoline-1,3-dione (2S,4R)-1-((S)-2-amino-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide hydrochloride tert-butyl 3,3'-(2-aMino-2-((3-tert-butoxy-3-oxopropoxy)Methyl)propane-1,3-diyl)bis(oxy)dipropanoateRelated product price
- 2-(2,6-dioxopiperidin-3-yl)-4-fluoroisoindoline-1,3-dione
$5-6247.5 - (2S,4R)-1-((S)-2-amino-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide hydrochloride
$20-1350 - tert-butyl 3,3'-(2-aMino-2-((3-tert-butoxy-3-oxopropoxy)Methyl)propane-1,3-diyl)bis(oxy)dipropanoate
$65-2500
Suppliers and manufacturers
Shanghai finete Pharmaceutical Co., Ltd.
ATK CHEMICAL COMPANY LIMITED
Accela ChemBio Inc.
Shaanxi Dideu Medichem Co. Ltd
Neostar United (Changzhou) Industrial Co., Ltd.
NINGBOBENKANGJS PHARMTECHCO., LTD
HANGZHOU CLAP TECHNOLOGY CO.,LTD
Baoji Guokang Bio-Technology Co., Ltd.