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ChemicalBook >> CAS DataBase List >> (2S,4R)-1-((S)-2-amino-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide hydrochloride

(2S,4R)-1-((S)-2-amino-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide hydrochloride

$20 - $1350
Product name: (2S,4R)-1-((S)-2-amino-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide hydrochloride
CAS: 1448189-80-7
MF: C22H31ClN4O3S
MW: 467.03
EINECS:604-604-1
MDL Number:
Synonyms:(2S,4R)-1-((S)-2-amino-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide hydrochloride;Protein degrader 1 (hydrochloride);(S,R,S)-AHPC hydrochloride;MDK-7526;ULM-1;(4R)-3-Methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-L-prolinamide hydrochloride;Protein degrader 1;141003;(2S,4R)-1-[(2S)-2-amino-3,3-dimethylbutanoyl]-4-hydroxy-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide hydrochloride

Price25 Properties Safety Information Description

25 prices

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Brand

Abosyn
AK Scientific
Ambeed
American Custom Chemicals Corporation
BroadPharm
Cayman Chemical
Chemenu
Crysdot
DC Chemicals
Iris Biotech GmbH
Sigma-Aldrich
TRC

Package

5mg
10mg
25mg
50mg
100mg
250mg
500mg
1g
2g
5g

ManufacturerAbosyn
Product number10-3468
Product description(2S,4R)-1-((S)-2-amino-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamidehydrochloride 95%-98%
Packaging1g
Price$695
Updated2021-12-16
Buy

ManufacturerAK Scientific
Product number5959EF
Product descriptionProteindegrader1hydrochloride
Packaging1g
Price$998
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA113059
Product description(2S,4R)-1-((S)-2-Amino-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamidehydrochloride 98%
Packaging5mg
Price$20
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA113059
Product description(2S,4R)-1-((S)-2-Amino-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamidehydrochloride 98%
Packaging25mg
Price$37
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA113059
Product description(2S,4R)-1-((S)-2-Amino-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamidehydrochloride 98%
Packaging50mg
Price$49
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA113059
Product description(2S,4R)-1-((S)-2-Amino-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamidehydrochloride 98%
Packaging100mg
Price$73
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA113059
Product description(2S,4R)-1-((S)-2-Amino-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamidehydrochloride 98%
Packaging250mg
Price$109
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA113059
Product description(2S,4R)-1-((S)-2-Amino-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamidehydrochloride 98%
Packaging1g
Price$272
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA113059
Product description(2S,4R)-1-((S)-2-Amino-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamidehydrochloride 98%
Packaging5g
Price$992
Updated2021-12-16
Buy

ManufacturerAmerican Custom Chemicals Corporation
Product numberINB0005701
Product description(2S,4R)-1-((S)-2-AMINO-3,3-DIMETHYLBUTANOYL)-4-HYDROXY-N-(4-(4-METHYLTHIAZOL-5-YL)BENZYL)PYRROLIDINE-2-CARBOXAMIDE HYDROCHLORIDE 95.00%
Packaging5MG
Price$456.82
Updated2021-12-16
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ManufacturerBroadPharm
Product numberBP-24441
Product descriptionVHLLigand1HClsalt 98%
Packaging250mg
Price$180
Updated2021-12-16
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ManufacturerCayman Chemical
Product number21591
Product descriptionVHL Ligand 1 (hydrochloride) ≥95%
Packaging100mg
Price$353
Updated2024-03-01
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ManufacturerCayman Chemical
Product number21591
Product descriptionVHL Ligand 1 (hydrochloride) ≥95%
Packaging50mg
Price$249
Updated2024-03-01
Buy

ManufacturerCayman Chemical
Product number21591
Product descriptionVHL Ligand 1 (hydrochloride) ≥95%
Packaging25mg
Price$151
Updated2024-03-01
Buy

ManufacturerCayman Chemical
Product number21591
Product descriptionVHL Ligand 1 (hydrochloride) ≥95%
Packaging10mg
Price$72
Updated2024-03-01
Buy

ManufacturerChemenu
Product numberCM328305
Product description(2S,4R)-1-[(2S)-2-amino-3,3-dimethylbutanoyl]-4-hydroxy-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide;hydrochloride 95%+
Packaging500mg
Price$96
Updated2021-12-16
Buy

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
Abosyn	10-3468	(2S,4R)-1-((S)-2-amino-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamidehydrochloride 95%-98%	1g	$695	2021-12-16	Buy
AK Scientific	5959EF	Proteindegrader1hydrochloride	1g	$998	2021-12-16	Buy
Ambeed	A113059	(2S,4R)-1-((S)-2-Amino-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamidehydrochloride 98%	5mg	$20	2021-12-16	Buy
Ambeed	A113059	(2S,4R)-1-((S)-2-Amino-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamidehydrochloride 98%	25mg	$37	2021-12-16	Buy
Ambeed	A113059	(2S,4R)-1-((S)-2-Amino-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamidehydrochloride 98%	50mg	$49	2021-12-16	Buy
Ambeed	A113059	(2S,4R)-1-((S)-2-Amino-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamidehydrochloride 98%	100mg	$73	2021-12-16	Buy
Ambeed	A113059	(2S,4R)-1-((S)-2-Amino-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamidehydrochloride 98%	250mg	$109	2021-12-16	Buy
Ambeed	A113059	(2S,4R)-1-((S)-2-Amino-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamidehydrochloride 98%	1g	$272	2021-12-16	Buy
Ambeed	A113059	(2S,4R)-1-((S)-2-Amino-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamidehydrochloride 98%	5g	$992	2021-12-16	Buy
American Custom Chemicals Corporation	INB0005701	(2S,4R)-1-((S)-2-AMINO-3,3-DIMETHYLBUTANOYL)-4-HYDROXY-N-(4-(4-METHYLTHIAZOL-5-YL)BENZYL)PYRROLIDINE-2-CARBOXAMIDE HYDROCHLORIDE 95.00%	5MG	$456.82	2021-12-16	Buy
BroadPharm	BP-24441	VHLLigand1HClsalt 98%	250mg	$180	2021-12-16	Buy
Cayman Chemical	21591	VHL Ligand 1 (hydrochloride) ≥95%	100mg	$353	2024-03-01	Buy
Cayman Chemical	21591	VHL Ligand 1 (hydrochloride) ≥95%	50mg	$249	2024-03-01	Buy
Cayman Chemical	21591	VHL Ligand 1 (hydrochloride) ≥95%	25mg	$151	2024-03-01	Buy
Cayman Chemical	21591	VHL Ligand 1 (hydrochloride) ≥95%	10mg	$72	2024-03-01	Buy
Chemenu	CM328305	(2S,4R)-1-[(2S)-2-amino-3,3-dimethylbutanoyl]-4-hydroxy-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide;hydrochloride 95%+	500mg	$96	2021-12-16	Buy

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Properties

storage temp. :2-8°C
solubility :DMF: 20 mg/ml; DMSO: 20 mg/ml; Ethanol: 20 mg/ml; PBS (pH 7.2): 10 mg/ml
form :A crystalline solid
color :White to yellow
InChIKey :JYRTWGCWUBURGU-XIMRXPCLNA-N
SMILES :C([C@@H]1C[C@@H](O)CN1C(=O)[C@@H](N)C(C)(C)C)(=O)NCC1C=CC(C2=C(N=CS2)C)=CC=1.Cl |&1:1,3,9,r|

Safety Information

Symbol(GHS):

Signal word:

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	Pictogram	P-Codes

Precautionary statements:

Description

VHL ligand 1 is a building block in the synthesis of proteolysis-targeting chimera technologies (PROTACs). It is the von Hippel-Lindau (VHL) E3 ligase binding portion of some VHL-based PROTACs, including BET PROTAC MZ1 (Item No. 21622).

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Zhengzhou Anbu Chem Co.,Ltd

$0.00 /1KG
(2S,4R)-1-((S)-2-amino-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide hydrochloride CAS:1448189-80-7

Shanghai finete Pharmaceutical Co., Ltd.

ATK CHEMICAL COMPANY LIMITED

Jinan Carbotang Biotech Co.,Ltd.

Accela ChemBio Inc.

Shanghai Worldyang Chemical Co.,Ltd.

Shochem(Shanghai) Co.,Ltd

BOC Sciences

Neostar United (Changzhou) Industrial Co., Ltd.

Zhengzhou Alfa Chemical Co.,Ltd

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(2S,4R)-1-((S)-2-amino-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide hydrochloride

Properties

Safety Information

Description

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