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ChemicalBook >> CAS DataBase List >> CP671305

CP671305

CP671305 price.
  • $44 - $2900
  • Product name: CP671305
  • CAS: 445295-04-5
  • MF: C23H19FN2O7
  • MW: 454.4
  • EINECS:
  • MDL Number:MFCD31382154
  • Synonyms:CP671305;CP-671305; CP 671305; CP671305; UNII-9LH034R9R9;445295-04-5;UNII-9LH034R9R9;CS-2886;Propanoic acid, 2-[4-[[[[2-(1,3-benzodioxol-5-yloxy)-3-pyridinyl]carbonyl]amino]methyl]-3-fluorophenoxy]-, (2R)-;(R)-2-(4-((2-(benzo[d][1,3]dioxol-5-yloxy)nicotinamido)methyl)-3-fluorophenoxy)propanoic acid;CP 671305,Inhibitor,Phosphodiesterase (PDE),CP671305,CP-671305,inhibit
17 prices
Selected condition：
Brand
  • AK Scientific
  • Biosynth Carbosynth
  • Cayman Chemical
  • ChemScene
  • DC Chemicals
Package
  • 2mg
  • 50
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • ManufacturerAK Scientific
  • Product number4497CR
  • Product description(2R)-2-[4-[[[2-(1,3-Benzodioxol-5-yloxy)pyridine-3-carbonyl]amino]methyl]-3-fluorophenoxy]propanoicacid
  • Packaging10mg
  • Price$299
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberBC161230
  • Product descriptionCP 671305
  • Packaging1mg
  • Price$175
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberBC161230
  • Product descriptionCP 671305
  • Packaging10mg
  • Price$185
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberBC161230
  • Product descriptionCP 671305
  • Packaging2mg
  • Price$250
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberBC161230
  • Product descriptionCP 671305
  • Packaging5mg
  • Price$500
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberBC161230
  • Product descriptionCP 671305
  • Packaging50
  • Price$647.5
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberBC161230
  • Product descriptionCP 671305
  • Packaging25mg
  • Price$1000
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number26743
  • Product descriptionCP 671,305
  • Packaging1mg
  • Price$44
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number26743
  • Product descriptionCP 671,305
  • Packaging5mg
  • Price$193
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number26743
  • Product descriptionCP 671,305
  • Packaging10mg
  • Price$341
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6774
  • Product descriptionCP671305 99.95%
  • Packaging5mg
  • Price$100
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6774
  • Product descriptionCP671305 99.95%
  • Packaging10mg
  • Price$150
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6774
  • Product descriptionCP671305 99.95%
  • Packaging25mg
  • Price$250
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6774
  • Product descriptionCP671305 99.95%
  • Packaging50mg
  • Price$450
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6774
  • Product descriptionCP671305 99.95%
  • Packaging100mg
  • Price$750
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC11410
  • Product descriptionCP-671305 >98%
  • Packaging5mg
  • Price$700
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 4497CR (2R)-2-[4-[[[2-(1,3-Benzodioxol-5-yloxy)pyridine-3-carbonyl]amino]methyl]-3-fluorophenoxy]propanoicacid 10mg $299 2021-12-16 Buy
Biosynth Carbosynth BC161230 CP 671305 1mg $175 2021-12-16 Buy
Biosynth Carbosynth BC161230 CP 671305 10mg $185 2021-12-16 Buy
Biosynth Carbosynth BC161230 CP 671305 2mg $250 2021-12-16 Buy
Biosynth Carbosynth BC161230 CP 671305 5mg $500 2021-12-16 Buy
Biosynth Carbosynth BC161230 CP 671305 50 $647.5 2021-12-16 Buy
Biosynth Carbosynth BC161230 CP 671305 25mg $1000 2021-12-16 Buy
Cayman Chemical 26743 CP 671,305 1mg $44 2024-03-01 Buy
Cayman Chemical 26743 CP 671,305 5mg $193 2024-03-01 Buy
Cayman Chemical 26743 CP 671,305 10mg $341 2024-03-01 Buy
ChemScene CS-6774 CP671305 99.95% 5mg $100 2021-12-16 Buy
ChemScene CS-6774 CP671305 99.95% 10mg $150 2021-12-16 Buy
ChemScene CS-6774 CP671305 99.95% 25mg $250 2021-12-16 Buy
ChemScene CS-6774 CP671305 99.95% 50mg $450 2021-12-16 Buy
ChemScene CS-6774 CP671305 99.95% 100mg $750 2021-12-16 Buy
DC Chemicals DC11410 CP-671305 >98% 5mg $700 2021-12-16 Buy

Properties

storage temp. :Store at -20°C
solubility :DMF: 50 mg/ml; DMSO: 25 mg/ml; Ethanol: 3 mg/ml; PBS (pH 7.2): 2 mg/ml
form :A crystalline solid
color :White to off-white

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

CP 671,305 is a potent inhibitor of phosphodiesterase 4D (PDE4D; IC50 = 3 nM). It is selective for PDE4D over PDE4A, -B, and -C (IC50s = 310, 287, and 3,858 nM, respectively), as well as over PDE1-3 and 5 (IC50s = >5,000 nM for all). CP 671,305 inhibits release of leukotriene E4 (LTE4; ) from eosinophils (IC50 = 52 nM) and LTB4 from neutrophils (IC50 = 106 nM). In vivo, CP 671,305 inhibits antigen-induced pulmonary eosinophil influx in cynomolgus monkeys in a dose-dependent manner.

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