CP 91149
- $49 - $576
- Product name: CP 91149
- CAS: 186392-40-5
- MF: C21H21ClN3O3
- MW: 398.86274
- EINECS:
- MDL Number:MFCD00954145
- Synonyms:[R-(R*,S*)]-5-Chloro-N-[3-(diMethylaMino)-2-hydroxy-3-oxo- 1-(phenylMethyl)propyl]-1H-indole-2-carboxaMide;5-Chloro-N-[(1S,2R)-3-(diMethylaMino)-2-hydroxy-3-oxo-1-(phenylMethyl)propyl]-1H-indole-2-carboxaMide;CP 91149;5-chloro-N-((2S,3R)-4-(dimethylamino)-3-hydroxy-4-oxo-1-phenylbutan-2-yl)-1H-indole-2-carboxamide;CP 91149 USP/EP/BP;CS-231;CP-91149 CP91149
14 prices
Selected condition:
Brand
- AK Scientific
- ApexBio Technology
- Cayman Chemical
- Chemenu
- Crysdot
- Sigma-Aldrich
- TRC
Package
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- ManufacturerAK Scientific
- Product numberX7603
- Product descriptionCP-91149
- Packaging25mg
- Price$271
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8403
- Product descriptionCP-91149
- Packaging5mg
- Price$68
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8403
- Product descriptionCP-91149
- Packaging10mg
- Price$123
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8403
- Product descriptionCP-91149
- Packaging25mg
- Price$238
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number17709
- Product descriptionCP 91,149 ≥98%
- Packaging5mg
- Price$62
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17709
- Product descriptionCP 91,149 ≥98%
- Packaging10mg
- Price$109
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17709
- Product descriptionCP 91,149 ≥98%
- Packaging25mg
- Price$211
- Updated2024-03-01
- Buy
- ManufacturerChemenu
- Product numberCM148965
- Product description5-chloro-N-((2S,3R)-4-(dimethylamino)-3-hydroxy-4-oxo-1-phenylbutan-2-yl)-1H-indole-2-carboxamide 95%
- Packaging100mg
- Price$209
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD11177950
- Product descriptionCP-91149 95+%
- Packaging10mg
- Price$49
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD11177950
- Product descriptionCP-91149 95+%
- Packaging50mg
- Price$140
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD11177950
- Product descriptionCP-91149 95+%
- Packaging100mg
- Price$224
- Updated2021-12-16
- Buy
- ManufacturerSigma-Aldrich
- Product numberPZ0104
- Product descriptionCP-91149 ≥98% (HPLC)
- Packaging5mg
- Price$147
- Updated2024-03-01
- Buy
- ManufacturerSigma-Aldrich
- Product numberPZ0104
- Product descriptionCP-91149 ≥98% (HPLC)
- Packaging25mg
- Price$576
- Updated2024-03-01
- Buy
- ManufacturerTRC
- Product numberC781360
- Product descriptionCP-91149
- Packaging10mg
- Price$90
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AK Scientific | X7603 | CP-91149 | 25mg | $271 | 2021-12-16 | Buy |
ApexBio Technology | A8403 | CP-91149 | 5mg | $68 | 2021-12-16 | Buy |
ApexBio Technology | A8403 | CP-91149 | 10mg | $123 | 2021-12-16 | Buy |
ApexBio Technology | A8403 | CP-91149 | 25mg | $238 | 2021-12-16 | Buy |
Cayman Chemical | 17709 | CP 91,149 ≥98% | 5mg | $62 | 2024-03-01 | Buy |
Cayman Chemical | 17709 | CP 91,149 ≥98% | 10mg | $109 | 2024-03-01 | Buy |
Cayman Chemical | 17709 | CP 91,149 ≥98% | 25mg | $211 | 2024-03-01 | Buy |
Chemenu | CM148965 | 5-chloro-N-((2S,3R)-4-(dimethylamino)-3-hydroxy-4-oxo-1-phenylbutan-2-yl)-1H-indole-2-carboxamide 95% | 100mg | $209 | 2021-12-16 | Buy |
Crysdot | CD11177950 | CP-91149 95+% | 10mg | $49 | 2021-12-16 | Buy |
Crysdot | CD11177950 | CP-91149 95+% | 50mg | $140 | 2021-12-16 | Buy |
Crysdot | CD11177950 | CP-91149 95+% | 100mg | $224 | 2021-12-16 | Buy |
Sigma-Aldrich | PZ0104 | CP-91149 ≥98% (HPLC) | 5mg | $147 | 2024-03-01 | Buy |
Sigma-Aldrich | PZ0104 | CP-91149 ≥98% (HPLC) | 25mg | $576 | 2024-03-01 | Buy |
TRC | C781360 | CP-91149 | 10mg | $90 | 2021-12-16 | Buy |
Properties
Melting point :190-192°C
storage temp. :2-8°C
solubility :DMSO: >20mg/mL
form :powder
color :white to off-white
Stability :Hygroscopic
storage temp. :2-8°C
solubility :DMSO: >20mg/mL
form :powder
color :white to off-white
Stability :Hygroscopic
Safety Information
Symbol(GHS): | |||||||||||||||
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Signal word: | Warning | ||||||||||||||
Hazard statements: |
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Precautionary statements: |
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Description
CP 91,149 is an inhibitor of human liver glycogen phosphorylase a (LGPa), muscle glycogen phosphorylase a (MGPa), and MGPb (IC50s = 0.13, 0.2, and 0.3 μM, respectively, in the presence of glucose). CP 91,149 is 5- to 10-fold less potent in the absence of glucose. In vitro, it inhibits glucagon-stimulated glycogenolysis in primary human hepatocytes (IC50 = 2.1 μM) and increases glycogen synthesis in rat hepatocytes at a concentration of 2.5 μM in the presence of 5 mM glucose. CP 91,149 inhibits brain GP (IC50 = 0.5 μM) and, at a concentration of 30 μM, inhibits glycogen accumulation and proliferation of A549 non-small cell lung carcinoma (NSCLC) cells that express endogenous brain GP. In vivo, CP 91,149 (25 mg/kg, p.o.) lowers the plasma glucose level in diabetic ob/ob mice within 3 hours of administration without producing hypoglycemia, but has no effect on normoglycemic, non-diabetic mice.More related product prices
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