CD437
- $60 - $2100
- Product name: CD437
- CAS: 125316-60-1
- MF: C27H26O3
- MW: 398.49
- EINECS:200-258-5
- MDL Number:MFCD03106506
- Synonyms:2-naphthalenecarboxylicacid,6-(4-hydroxy-3-tricyclo(3.3.1.1(3,7))dec-1-ylphen ;6-(4-hydroxy-3-tricyclo(3.3.1.1(3,7))dec-1-ylphenyl)-2-naphthalenecarboxylic ;AHPN, 6-[3-(1-Adamantyl)-4-hydroxyphenyl]-2-naphthalene carboxylic acid;O-DesMethyl Adapalene;CD 437/AHPN;Adapalene IMpurity F;Apoptosis Activator VI, CD437/AHPN ;ADAP-IME
32 prices
Selected condition:
Brand
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Biosynth Carbosynth
- Cayman Chemical
- ChemScene
- DC Chemicals
- Sigma-Aldrich
- TRC
Package
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250MG
- 1g
- ManufacturerAK Scientific
- Product number4426BA
- Product description6-[3-(1-Adamantyl)-4-hydroxyphenyl]-2-naphthalenecarboxylicAcid
- Packaging1g
- Price$2085
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA570556
- Product descriptionCD-437 98+%
- Packaging5mg
- Price$112
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA570556
- Product descriptionCD-437 98+%
- Packaging10mg
- Price$156
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA570556
- Product descriptionCD-437 98+%
- Packaging25mg
- Price$265
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA570556
- Product descriptionCD-437 98+%
- Packaging100mg
- Price$584
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberCHM0294494
- Product descriptionO-DESMETHYL ADAPALENE 95.00%
- Packaging25MG
- Price$739.2
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberCHM0294494
- Product descriptionO-DESMETHYL ADAPALENE 95.00%
- Packaging250MG
- Price$1871.1
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB6785
- Product descriptionCD437
- Packaging5mg
- Price$126
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB6785
- Product descriptionCD437
- Packaging10mg
- Price$189
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB6785
- Product descriptionCD437
- Packaging25mg
- Price$410
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB6785
- Product descriptionCD437
- Packaging50mg
- Price$725
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB6785
- Product descriptionCD437
- Packaging100mg
- Price$1292
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFD21233
- Product descriptionO-Desmethyl adapalene
- Packaging10mg
- Price$139.8
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFD21233
- Product descriptionO-Desmethyl adapalene
- Packaging25mg
- Price$254.5
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFD21233
- Product descriptionO-Desmethyl adapalene
- Packaging50mg
- Price$462
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFD21233
- Product descriptionO-Desmethyl adapalene
- Packaging100mg
- Price$840
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AK Scientific | 4426BA | 6-[3-(1-Adamantyl)-4-hydroxyphenyl]-2-naphthalenecarboxylicAcid | 1g | $2085 | 2021-12-16 | Buy |
Ambeed | A570556 | CD-437 98+% | 5mg | $112 | 2021-12-16 | Buy |
Ambeed | A570556 | CD-437 98+% | 10mg | $156 | 2021-12-16 | Buy |
Ambeed | A570556 | CD-437 98+% | 25mg | $265 | 2021-12-16 | Buy |
Ambeed | A570556 | CD-437 98+% | 100mg | $584 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | CHM0294494 | O-DESMETHYL ADAPALENE 95.00% | 25MG | $739.2 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | CHM0294494 | O-DESMETHYL ADAPALENE 95.00% | 250MG | $1871.1 | 2021-12-16 | Buy |
ApexBio Technology | B6785 | CD437 | 5mg | $126 | 2021-12-16 | Buy |
ApexBio Technology | B6785 | CD437 | 10mg | $189 | 2021-12-16 | Buy |
ApexBio Technology | B6785 | CD437 | 25mg | $410 | 2021-12-16 | Buy |
ApexBio Technology | B6785 | CD437 | 50mg | $725 | 2021-12-16 | Buy |
ApexBio Technology | B6785 | CD437 | 100mg | $1292 | 2021-12-16 | Buy |
Biosynth Carbosynth | FD21233 | O-Desmethyl adapalene | 10mg | $139.8 | 2021-12-16 | Buy |
Biosynth Carbosynth | FD21233 | O-Desmethyl adapalene | 25mg | $254.5 | 2021-12-16 | Buy |
Biosynth Carbosynth | FD21233 | O-Desmethyl adapalene | 50mg | $462 | 2021-12-16 | Buy |
Biosynth Carbosynth | FD21233 | O-Desmethyl adapalene | 100mg | $840 | 2021-12-16 | Buy |
Properties
Melting point :271.6-276 °C
Boiling point :595.0±50.0 °C(Predicted)
Density :1.290
storage temp. :-20°C
solubility :DMSO: 26 mg/mL
form :solid
pka :4.17±0.30(Predicted)
color :yellow
Boiling point :595.0±50.0 °C(Predicted)
Density :1.290
storage temp. :-20°C
solubility :DMSO: 26 mg/mL
form :solid
pka :4.17±0.30(Predicted)
color :yellow
Safety Information
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Signal word: | Warning | ||||||||||||||
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Description
CD437 is the prototypical adamantyl arotinoid of the retinoid-related molecule family that acts as a selective agonist of retinoic acid receptor (RAR)γ (Kds = 6.5 μM, 2.5 μM, and 77 nM for RARα, β, and γ, respectively). CD437 is cytotoxic to the acute myeloid leukemia cell line NB4 (EC50 = 0.17 μM), inducing DNA damage by producing DNA double strand breaks. CD437 also induces cell cycle arrest and apoptosis in various other cancer cells including melanoma, breast, non-small lung, and prostate cancer cells through RAR-dependent and -independent signaling pathways.More related product prices
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