Birinapant
|
- $57 - $4023.9
- Product name: Birinapant
- CAS: 1260251-31-7
- MF: C42H56F2N8O6
- MW: 806.94
- EINECS:
- MDL Number:MFCD25976869
- Synonyms:Birinapant;Birinapant (TL32711);TL 32711;Birinapant(TL32711)/TL-32711/TL32711/TL-32711;(2S,2'S)-N,N'-[(6,6'-Difluoro[2,2'-bi-1H-indole]-3,3'-diyl)bis[methylene[(2R,4S)-4-hydroxy-2,1-pyrrolidinediyl][(1S)-1-ethyl-2-oxo-2,1-ethanediyl]]]bis[2-(methylamino)-propanamide;Propanamide, N,N'-[(6,6'-difluoro[2,2'-bi-1H-indole]-3,3'-diyl)bis[methylene[(2R,4S)-4-hydroxy-2,1-pyrrolidinediyl][(1S)-1-ethyl-2-oxo-2,1-ethanediyl]]]bis[2-(methylamino)-, (2S,2'S)-;(2S,2'S)-N,N'-[(6,6'-Difluoro[2,2'-bi-1H-indole]-3,3'-diyl)bis[methylene[(2R,4S)-4-hydroxy-2,1-pyrrolidinediyl][(1S)-1-ethyl-2-oxo-2,1-ethanediyl]]]bis[2-(methylamino)-propanamide Birinapant TL 32711;Birinapant (2S,2'S)-N,N'-[(6,6'-Difluoro[2,2'-bi-1H-indole]-3,3'-diyl)bis[methylene[(2R,4S)-4-hydroxy-2,1-pyrrolidinediyl][(1S)-1-ethyl-2-oxo-2,1-ethanediyl]]]bis[2-(methylamino)-propanamide
16 prices
Selected condition：
Brand
- AK Scientific
- ApexBio Technology
- Arctom
- Biorbyt Ltd
- Cayman Chemical
- Crysdot
- DC Chemicals
- TRC
Package
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1g
- ManufacturerAK Scientific
- Product numberSYN5734
- Product descriptionBirinapant
- Packaging10mg
- Price$170
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4219
- Product descriptionBirinapant(TL32711)
- Packaging5mg
- Price$90
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberCFN60279
- Product descriptionBirinapant ≥98%
- Packaging10mg
- Price$288
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb146223
- Product descriptionBirinapant (TL32711) >98%
- Packaging100mg
- Price$986
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb146223
- Product descriptionBirinapant (TL32711) >98%
- Packaging250mg
- Price$1949.9
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb146223
- Product descriptionBirinapant (TL32711) >98%
- Packaging1g
- Price$4023.9
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number19699
- Product descriptionBirinapant ≥95%
- Packaging1mg
- Price$57
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number19699
- Product descriptionBirinapant ≥95%
- Packaging5mg
- Price$193
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number19699
- Product descriptionBirinapant ≥95%
- Packaging10mg
- Price$330
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number19699
- Product descriptionBirinapant ≥95%
- Packaging25mg
- Price$616
- Updated2024-03-01
- Buy
- ManufacturerCrysdot
- Product numberCD31004061
- Product descriptionBirinapant 98+%
- Packaging5mg
- Price$126
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31004061
- Product descriptionBirinapant 98+%
- Packaging10mg
- Price$196
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31004061
- Product descriptionBirinapant 98+%
- Packaging50mg
- Price$595
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31004061
- Product descriptionBirinapant 98+%
- Packaging100mg
- Price$945
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC5023
- Product descriptionBirinapant(TL32711) >98%
- Packaging1g
- Price$2700
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberB399730
- Product descriptionBirinapant
- Packaging5mg
- Price$140
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | SYN5734 | Birinapant | 10mg | $170 | 2021-12-16 | Buy |
| ApexBio Technology | A4219 | Birinapant(TL32711) | 5mg | $90 | 2021-12-16 | Buy |
| Arctom | CFN60279 | Birinapant ≥98% | 10mg | $288 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb146223 | Birinapant (TL32711) >98% | 100mg | $986 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb146223 | Birinapant (TL32711) >98% | 250mg | $1949.9 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb146223 | Birinapant (TL32711) >98% | 1g | $4023.9 | 2021-12-16 | Buy |
| Cayman Chemical | 19699 | Birinapant ≥95% | 1mg | $57 | 2024-03-01 | Buy |
| Cayman Chemical | 19699 | Birinapant ≥95% | 5mg | $193 | 2024-03-01 | Buy |
| Cayman Chemical | 19699 | Birinapant ≥95% | 10mg | $330 | 2024-03-01 | Buy |
| Cayman Chemical | 19699 | Birinapant ≥95% | 25mg | $616 | 2024-03-01 | Buy |
| Crysdot | CD31004061 | Birinapant 98+% | 5mg | $126 | 2021-12-16 | Buy |
| Crysdot | CD31004061 | Birinapant 98+% | 10mg | $196 | 2021-12-16 | Buy |
| Crysdot | CD31004061 | Birinapant 98+% | 50mg | $595 | 2021-12-16 | Buy |
| Crysdot | CD31004061 | Birinapant 98+% | 100mg | $945 | 2021-12-16 | Buy |
| DC Chemicals | DC5023 | Birinapant(TL32711) >98% | 1g | $2700 | 2021-12-16 | Buy |
| TRC | B399730 | Birinapant | 5mg | $140 | 2021-12-16 | Buy |
Properties
Melting point :>245oC (dec.)
Boiling point :1090.5±65.0 °C(Predicted)
Density :1.320±0.06(20.0000℃)
storage temp. :-20°C Freezer
solubility :Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
pka :13.99±0.46(Predicted)
form :Solid
color :White to Off-White
Boiling point :1090.5±65.0 °C(Predicted)
Density :1.320±0.06(20.0000℃)
storage temp. :-20°C Freezer
solubility :Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
pka :13.99±0.46(Predicted)
form :Solid
color :White to Off-White
Safety Information
| Symbol(GHS): |
|
|||||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Signal word: | Warning | |||||||||||||||||||||||||||||||||||
| Hazard statements: |
|
|||||||||||||||||||||||||||||||||||
| Precautionary statements: |
|
Description
Birinapant is a bivalent mimetic of the Diablo homolog known as second mitochondria-derived activator of caspase (Smac). It is an antagonist of cellular inhibitor of apoptosis 1 (cIAP1, or BIRC2), cIAP2 (BIRC3), and XIAP (BIRC4), binding each at nanomolar concentrations. Birinapant causes rapid cIAP1 degradation, caspase activation, PARP cleavage, and NF-κB activation in breast cancer cells. It shows in vivo antitumor activity, inducing apoptosis in several types of cancer xenografts in mice.Related product price
- 918504-65-1
$29-3960 - GDC-0152
$44-550 - MG-132
$11-1000
