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ChemicalBook >> CAS DataBase List >> Azilsartan

Azilsartan

Azilsartan price.
  • $5 - $950
  • Product name: Azilsartan
  • CAS: 147403-03-0
  • MF: C25H20N4O5
  • MW: 456.45
  • EINECS:808-058-6
  • MDL Number:MFCD20278186
  • Synonyms:AZILSARTAN;2-Ethoxy-1-[[2'-(4,5-dihydro-5-oxo-1,2,4-oxadiazol-3-yl)biphenyl-4-yl]methyl]benzimidazole-7-carboxylic acid Azilsartan;2-ethoxy -1- {[2'-(5-oxo-4,5-dihydro -1,2,4 -oxadiazol-3-yl) biphenyl-4-yl ] methyl} -1H –benzimi[d]dazole-7-carboxylic acid;2-ethoxy-1-((2'-(5-oxo-4,5-dihydro- 1,2,4-oxadiazol-3-yl)-[1,1'-biphenyl]-4-yl)methyl)-1H-benzo[d]imidazole-7-carboxylic acid;2-Ethoxy-1-[[2'-(4,5-dihydro-5-oxo-1,2,4-oxadiazol-3-yl)biphenyl-4-yl]methyl]benzimidazole-7-carboxylic acid;Tak 536;Unii-F9nux55p23;2-ethoxy-3-((2'-(5-oxo-2,5-dihydro-1,2,4-oxadiazol-3-yl)biphenyl-4-yl)Methyl)-3H-benzo[d]iMidazole-4-carboxylic acid
45 prices
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Brand
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • AvaChem
  • Biorbyt Ltd
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chemcia Scientific
  • Chem-Impex
  • ChemScene
  • Crysdot
  • CSNpharm
  • DC Chemicals
  • Sigma-Aldrich
  • TCI Chemical
  • Tocris
  • TRC
  • Usbiological
Package
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  • 1MG
  • 50
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  • 50mg
  • 100mg
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  • 250mg
  • 500mg
  • 1g
  • 5g
  • 10g
  • 25g
  • 10mM(in 1mL DMSO)
  • ManufacturerAK Scientific
  • Product numberJ11584
  • Product descriptionAzilsartan
  • Packaging5mg
  • Price$30
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberB671
  • Product descriptionAzilsartan
  • Packaging5g
  • Price$367
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberB671
  • Product descriptionAzilsartan
  • Packaging10g
  • Price$401
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA217890
  • Product descriptionAzilsartan 98+%
  • Packaging50mg
  • Price$5
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA217890
  • Product descriptionAzilsartan 98+%
  • Packaging100mg
  • Price$7
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA217890
  • Product descriptionAzilsartan 98+%
  • Packaging250mg
  • Price$11
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA217890
  • Product descriptionAzilsartan 98+%
  • Packaging1g
  • Price$26
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA217890
  • Product descriptionAzilsartan 98+%
  • Packaging5g
  • Price$92
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA217890
  • Product descriptionAzilsartan 98+%
  • Packaging25g
  • Price$343
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0006315
  • Product descriptionTAK-536 95.00%
  • Packaging1MG
  • Price$405
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0006315
  • Product descriptionTAK-536 95.00%
  • Packaging10MG
  • Price$450
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB2210
  • Product descriptionAzilsartan
  • Packaging10mg
  • Price$45
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB2210
  • Product descriptionAzilsartan
  • Packaging10mM(in 1mL DMSO)
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB2210
  • Product descriptionAzilsartan
  • Packaging50mg
  • Price$100
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2976
  • Product descriptionAzilsartan
  • Packaging10mg
  • Price$65
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2976
  • Product descriptionAzilsartan
  • Packaging100mg
  • Price$249
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific J11584 Azilsartan 5mg $30 2021-12-16 Buy
AK Scientific B671 Azilsartan 5g $367 2021-12-16 Buy
AK Scientific B671 Azilsartan 10g $401 2021-12-16 Buy
Ambeed A217890 Azilsartan 98+% 50mg $5 2021-12-16 Buy
Ambeed A217890 Azilsartan 98+% 100mg $7 2021-12-16 Buy
Ambeed A217890 Azilsartan 98+% 250mg $11 2021-12-16 Buy
Ambeed A217890 Azilsartan 98+% 1g $26 2021-12-16 Buy
Ambeed A217890 Azilsartan 98+% 5g $92 2021-12-16 Buy
Ambeed A217890 Azilsartan 98+% 25g $343 2021-12-16 Buy
American Custom Chemicals Corporation API0006315 TAK-536 95.00% 1MG $405 2021-12-16 Buy
American Custom Chemicals Corporation API0006315 TAK-536 95.00% 10MG $450 2021-12-16 Buy
ApexBio Technology B2210 Azilsartan 10mg $45 2021-12-16 Buy
ApexBio Technology B2210 Azilsartan 10mM(in 1mL DMSO) $50 2021-12-16 Buy
ApexBio Technology B2210 Azilsartan 50mg $100 2021-12-16 Buy
AvaChem 2976 Azilsartan 10mg $65 2021-12-16 Buy
AvaChem 2976 Azilsartan 100mg $249 2021-12-16 Buy

Properties

Melting point :188 °C(dec.)
Density :1.42
storage temp. :Sealed in dry,2-8°C
solubility :DMSO: soluble15mg/mL (clear solution)
form :powder
pka :2.05±0.10(Predicted)
color :white to beige
InChIKey :KGSXMPPBFPAXLY-UHFFFAOYSA-N

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H361 Suspected of damaging fertility or the unborn child Reproductive toxicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
H413 May cause long lasting harmful effects to aquatic life Hazardous to the aquatic environment, long-term hazard Category 4
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Azilsartan is an antagonist of the angiotensin II type 1 receptor (AT1; IC50 = 0.42 μM) and the active metabolite of azilsartan medoxomil . Azilsartan is formed from azilsartan medoxomil by hydrolysis in the gastrointestinal tract and liver. Azilsartan also acts as an inverse agonist, inhibiting angiotensin II-induced accumulation of inositol-1-phosphate in COS-7 cells expressing recombinant human AT1 (IC50 = 2.6 nM). It reduces the maximal contractile response induced by angiotensin II in isolated rabbit aortic strips (pD2 = 9.9). Azilsartan (100 ng/kg, i.v.) inhibits the angiotensin II-induced pressor response in conscious normotensive rats.

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