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ChemicalBook >> CAS DataBase List >> (-)-Arctigenin

(-)-Arctigenin

(-)-Arctigenin price.
  • $9 - $1802
  • Product name: (-)-Arctigenin
  • CAS: 7770-78-7
  • MF: C21H24O6
  • MW: 372.41
  • EINECS:
  • MDL Number:MFCD00870597
  • Synonyms:(3R,4R)-4-[(3,4-DIMETHOXYPHENYL)METHYL]DIHYDRO-3-[(4-HYDROXY-3-METHOXYPHENYL)METHYL]-2(3H)-FURANONE;2(3H)-FURANONE,4-[(3,4-DIMETHOXYPHENYL)METHYL]DIHYDRO-3-[(4-HYDROXY-3-METHOXYPHENYL)METHYL]-,(3R,4R);2(3H)-FURANONE,4-[(3,4-DIMETHOXYPHENYL)METHYL]DIHYDRO-3-[(4-HYDROXY-3-METHOXYPHENYL)METHYL];ARCTIGENIN:2(3H)-FURANONE,4-[(3,4-DIMETHOXYPHENYL)METHYL]DIHYDRO-3-[(4-HYDROXY-3-METHOXYPHENYL)METHYL]-,(3R,4R);2(3H)-Furanone,4-[(3,4-dimethoxyphenyl) methyl];dihydro-3-[(4-hydroxy-3-methoxyphenyl)methyl]-,(3R,4R)-;(-)-ARCTIGENIN;ARCTIGENIN
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  • AccelPharmtech
  • Adipogen Life Sciences
  • AK Scientific
  • Ambeed
  • ApexBio Technology
  • Arctom
  • AvaChem
  • Biorbyt Ltd
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chem-Impex
  • ChemScene
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  • Medical Isotopes, Inc.
  • Sigma-Aldrich
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  • ManufacturerAccelPharmtech
  • Product numberAT0779
  • Product description(-)-arctigenin 99%
  • Packaging25G
  • Price$530
  • Updated2021-12-16
  • Buy
  • ManufacturerAccelPharmtech
  • Product numberAT0779
  • Product description(-)-arctigenin 99%
  • Packaging100G
  • Price$1690
  • Updated2021-12-16
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  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CN2-0530-M050
  • Product description(-)-Arctigenin ≥99%(HPLC)
  • Packaging50mg
  • Price$135
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberV0150
  • Product description(-)-Arctigenin
  • Packaging10mg
  • Price$72
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberV0150
  • Product description(-)-Arctigenin
  • Packaging50mg
  • Price$78
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberV0150
  • Product description(-)-Arctigenin
  • Packaging100mg
  • Price$85
  • Updated2021-12-16
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  • ManufacturerAK Scientific
  • Product numberV0150
  • Product description(-)-Arctigenin
  • Packaging250mg
  • Price$96
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberV0150
  • Product description(-)-Arctigenin
  • Packaging1g
  • Price$155
  • Updated2021-12-16
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  • ManufacturerAK Scientific
  • Product numberV0150
  • Product description(-)-Arctigenin
  • Packaging5g
  • Price$366
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA420992
  • Product description(3R,4R)-4-(3,4-Dimethoxybenzyl)-3-(4-hydroxy-3-methoxybenzyl)dihydrofuran-2(3H)-one 98+%
  • Packaging10mg
  • Price$9
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA420992
  • Product description(3R,4R)-4-(3,4-Dimethoxybenzyl)-3-(4-hydroxy-3-methoxybenzyl)dihydrofuran-2(3H)-one 98+%
  • Packaging50mg
  • Price$14
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA420992
  • Product description(3R,4R)-4-(3,4-Dimethoxybenzyl)-3-(4-hydroxy-3-methoxybenzyl)dihydrofuran-2(3H)-one 98+%
  • Packaging100mg
  • Price$27
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA420992
  • Product description(3R,4R)-4-(3,4-Dimethoxybenzyl)-3-(4-hydroxy-3-methoxybenzyl)dihydrofuran-2(3H)-one 98+%
  • Packaging250mg
  • Price$40
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA420992
  • Product description(3R,4R)-4-(3,4-Dimethoxybenzyl)-3-(4-hydroxy-3-methoxybenzyl)dihydrofuran-2(3H)-one 98+%
  • Packaging1g
  • Price$98
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA420992
  • Product description(3R,4R)-4-(3,4-Dimethoxybenzyl)-3-(4-hydroxy-3-methoxybenzyl)dihydrofuran-2(3H)-one 98+%
  • Packaging5g
  • Price$330
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberN2399
  • Product descriptionArctigenin
  • Packaging10mM(in 1mL DMSO)
  • Price$50
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AccelPharmtech AT0779 (-)-arctigenin 99% 25G $530 2021-12-16 Buy
AccelPharmtech AT0779 (-)-arctigenin 99% 100G $1690 2021-12-16 Buy
Adipogen Life Sciences AG-CN2-0530-M050 (-)-Arctigenin ≥99%(HPLC) 50mg $135 2021-12-16 Buy
AK Scientific V0150 (-)-Arctigenin 10mg $72 2021-12-16 Buy
AK Scientific V0150 (-)-Arctigenin 50mg $78 2021-12-16 Buy
AK Scientific V0150 (-)-Arctigenin 100mg $85 2021-12-16 Buy
AK Scientific V0150 (-)-Arctigenin 250mg $96 2021-12-16 Buy
AK Scientific V0150 (-)-Arctigenin 1g $155 2021-12-16 Buy
AK Scientific V0150 (-)-Arctigenin 5g $366 2021-12-16 Buy
Ambeed A420992 (3R,4R)-4-(3,4-Dimethoxybenzyl)-3-(4-hydroxy-3-methoxybenzyl)dihydrofuran-2(3H)-one 98+% 10mg $9 2021-12-16 Buy
Ambeed A420992 (3R,4R)-4-(3,4-Dimethoxybenzyl)-3-(4-hydroxy-3-methoxybenzyl)dihydrofuran-2(3H)-one 98+% 50mg $14 2021-12-16 Buy
Ambeed A420992 (3R,4R)-4-(3,4-Dimethoxybenzyl)-3-(4-hydroxy-3-methoxybenzyl)dihydrofuran-2(3H)-one 98+% 100mg $27 2021-12-16 Buy
Ambeed A420992 (3R,4R)-4-(3,4-Dimethoxybenzyl)-3-(4-hydroxy-3-methoxybenzyl)dihydrofuran-2(3H)-one 98+% 250mg $40 2021-12-16 Buy
Ambeed A420992 (3R,4R)-4-(3,4-Dimethoxybenzyl)-3-(4-hydroxy-3-methoxybenzyl)dihydrofuran-2(3H)-one 98+% 1g $98 2021-12-16 Buy
Ambeed A420992 (3R,4R)-4-(3,4-Dimethoxybenzyl)-3-(4-hydroxy-3-methoxybenzyl)dihydrofuran-2(3H)-one 98+% 5g $330 2021-12-16 Buy
ApexBio Technology N2399 Arctigenin 10mM(in 1mL DMSO) $50 2021-12-16 Buy

Properties

Melting point :98.0 to 102.0 °C
Boiling point :567.0±45.0 °C(Predicted)
Density :1.227±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :DMSO: 34 mg/mL with heating and sonicating, soluble
form :solid
pka :10.03±0.20(Predicted)
color :White to Light yellow
λmax :280nm(EtOH)(lit.)
InChI :InChI=1S/C21H24O6/c1-24-18-7-5-13(11-20(18)26-3)8-15-12-27-21(23)16(15)9-14-4-6-17(22)19(10-14)25-2/h4-7,10-11,15-16,22H,8-9,12H2,1-3H3/t15-,16+/m0/s1
InChIKey :NQWVSMVXKMHKTF-JKSUJKDBSA-N
SMILES :O1C[C@H](CC2=CC=C(OC)C(OC)=C2)[C@@H](CC2=CC=C(O)C(OC)=C2)C1=O
LogP :2.470 (est)
CAS DataBase Reference :7770-78-7(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Arctigenin is an extract from A. lappa, a burdock plant traditionally used in Japanese Kampo medicine for its antioxidant, anti-inflammatory, antiproliferative, and antiviral activity. At 0.1 μM, arctigenin can block the activation of Akt induced by glucose starvation in pancreatic cancer PANC-1 cells, which is a key process in the tolerance exhibited by cancer cells to glucose starvation. It has potent in vitro antiviral activities against in?uenza A virus and shows neuroprotective effects against an experimental mouse model of Japanese encephalitis. Arctigenin also demonstrates a therapeutic effect in ischemic stroke treatment of middle cerebral artery occluded rats by suppressing microglia activation and decreasing IL-1β and TNF-α expression.

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