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ChemicalBook >> CAS DataBase List >> Anidulafungin

Anidulafungin

Anidulafungin price.
  • $32 - $4321.4
  • Product name: Anidulafungin
  • CAS: 166663-25-8
  • MF: C58H73N7O17
  • MW: 1140.24
  • EINECS:658-060-4
  • MDL Number:MFCD00917070
  • Synonyms:Anidulafungin;Echinocandin B, 1-(4R,5R)-4,5-dihydroxy-N2-4-(pentyloxy)1,1:4,1-terphenyl-4-ylcarbonyl-L-ornithine-;Anidulafungin(LY303366);Ecalta;LY 303366;LY 303366, Eraxis;1-[(4R,5R)-4,5-dihydroxy-N2-[[4''-(pentyloxy)[1,1'',1''-terphenyl]-4-yl]carbonyl]-L-ornithine]-echinocandin B;Anidulafungin-d11
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Brand
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • AvaChem
  • Biorbyt Ltd
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • CSNpharm
  • DC Chemicals
  • Medical Isotopes, Inc.
  • TRC
  • Usbiological
Package
  • 10mM(in 1mL DMSO)
  • 0.5mg
  • 500ug
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • 10G
  • ManufacturerAK Scientific
  • Product numberB624
  • Product descriptionAnidulafungin
  • Packaging5mg
  • Price$127
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberB624
  • Product descriptionAnidulafungin
  • Packaging100mg
  • Price$585
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA156909
  • Product descriptionAnidulafungin 99+%
  • Packaging5mg
  • Price$144
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA156909
  • Product descriptionAnidulafungin 99+%
  • Packaging10mg
  • Price$187
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA156909
  • Product descriptionAnidulafungin 99+%
  • Packaging25mg
  • Price$242
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA156909
  • Product descriptionAnidulafungin 99+%
  • Packaging50mg
  • Price$314
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA156909
  • Product descriptionAnidulafungin 99+%
  • Packaging100mg
  • Price$408
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0001503
  • Product descriptionANIDULAFUNGIN 95.00%
  • Packaging10MG
  • Price$274.05
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0001503
  • Product descriptionANIDULAFUNGIN 95.00%
  • Packaging10G
  • Price$3759.53
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1224
  • Product descriptionAnidulafungin
  • Packaging10mM(in 1mL DMSO)
  • Price$95
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberB1224
  • Product descriptionAnidulafungin
  • Packaging100mg
  • Price$238
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1224
  • Product descriptionAnidulafungin
  • Packaging250mg
  • Price$485
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2671
  • Product descriptionAnidulafungin
  • Packaging5mg
  • Price$45
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2671
  • Product descriptionAnidulafungin
  • Packaging10mg
  • Price$75
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2671
  • Product descriptionAnidulafungin
  • Packaging50mg
  • Price$195
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2671
  • Product descriptionAnidulafungin
  • Packaging100mg
  • Price$290
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific B624 Anidulafungin 5mg $127 2021-12-16 Buy
AK Scientific B624 Anidulafungin 100mg $585 2021-12-16 Buy
Ambeed A156909 Anidulafungin 99+% 5mg $144 2021-12-16 Buy
Ambeed A156909 Anidulafungin 99+% 10mg $187 2021-12-16 Buy
Ambeed A156909 Anidulafungin 99+% 25mg $242 2021-12-16 Buy
Ambeed A156909 Anidulafungin 99+% 50mg $314 2021-12-16 Buy
Ambeed A156909 Anidulafungin 99+% 100mg $408 2021-12-16 Buy
American Custom Chemicals Corporation API0001503 ANIDULAFUNGIN 95.00% 10MG $274.05 2021-12-16 Buy
American Custom Chemicals Corporation API0001503 ANIDULAFUNGIN 95.00% 10G $3759.53 2021-12-16 Buy
ApexBio Technology B1224 Anidulafungin 10mM(in 1mL DMSO) $95 2021-12-16 Buy
ApexBio Technology B1224 Anidulafungin 100mg $238 2021-12-16 Buy
ApexBio Technology B1224 Anidulafungin 250mg $485 2021-12-16 Buy
AvaChem 2671 Anidulafungin 5mg $45 2021-12-16 Buy
AvaChem 2671 Anidulafungin 10mg $75 2021-12-16 Buy
AvaChem 2671 Anidulafungin 50mg $195 2021-12-16 Buy
AvaChem 2671 Anidulafungin 100mg $290 2021-12-16 Buy

Properties

Melting point :>196°C (subl.)
Boiling point :1477.0±65.0 °C(Predicted)
Density :1.47±0.1 g/cm3(Predicted)
storage temp. :under inert gas (nitrogen or Argon) at 2-8°C
solubility :DMSO (Slightly, Heated), Methanol (Slightly)
pka :9.86±0.26(Predicted)
form :Solid
color :White to Pale Beige

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H361 Suspected of damaging fertility or the unborn child Reproductive toxicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P281 Use personal protective equipment as required.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P330 Rinse mouth.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Anidulafungin, a semi-synthetic derivative of echinocandin B, has been developed and launched as an intravenous treatment for serious fungal infections, such as candidemia, Candida-derived peritonitis, intra-abdominal abscesses, and esophageal candidiasis. As a non-competitive inhibitor of 1,3-b-D-glucan synthase, which is responsible for the formation of glucan polymers, anidulafungin interferes with the cell wall synthesis of most pathogenic fungi. This mode of action is characteristic of the echinocandin class of antifungals. While the first member of this class, cilofungin, was withdrawn due to toxicity associated with the formulation vehicle, anidulafungin follows the successful introduction of caspofungin and micafungin. Compared to the other echinocandins, anidulafungin appears to be more potent (MIC90 ofr0.25 mg/mL for C.albicans, 0.5 mg/mL for C.glabrata, 1 mg/mL for C. krusel and C.tropicalis, 2mg/mL for C.lusitaniae, and 2 mg/mL for Aspergillus spp) and is devoid of significant drug interactions since it is neither an inhibitor nor substrate of the cytochrome P450 isoenzymes. The emergence of the echinocandins circumvents the concern regarding the rising resistance to the azole and amphotericin B antifungals; no cross-resistance is expected because the echinocandins work at the cell wall rather than the cell membrane.

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