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ChemicalBook >> CAS DataBase List >> Abacavir

Abacavir

Abacavir price.
  • $5 - $1580
  • Product name: Abacavir
  • CAS: 136470-78-5
  • MF: C14H18N6O
  • MW: 286.33
  • EINECS:620-487-9
  • MDL Number:MFCD00903850
  • Synonyms:1592u89 ;[(1s,4r)-4-[2-amino-6-(cyclopropylamino)purin-9-yl]-1-cyclopent-2-enyl]methanol;[(1S,4R)-4-(2-AMINO-6-CYCLOPROPYLAMINO-PURIN-9-YL)-CYCLOPENT-2-ENYL]-METHANOL;2-Cyclopentene-1-methanol, 4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]-, (1S,4R)-;2-Cyclopentene-1-methanol, 4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]-, (1S-cis)-;(+/-)-4-[2-amino-6-(cyclopropylamino)-9h-purin-9-yl]-2-cyclopentene-1-methanol;Abacavir;Abacavir (see A105000)
41 prices
Selected condition：
Brand
  • AHH
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • AvaChem
  • Biosynth Carbosynth
  • Chem-Impex
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Matrix Scientific
  • Medical Isotopes, Inc.
  • TCI Chemical
  • TRC
  • Usbiological
Package
  • 10mM(in 1mL H2O)
  • 5mg
  • 10mg
  • 50mg
  • 0.1g
  • 100mg
  • 200mg
  • 500mg
  • 1g
  • 2g
  • 5g
  • 10g
  • 25g
  • 100g
  • ManufacturerAHH
  • Product numberAPI-1167
  • Product descriptionAbacavir 98%
  • Packaging0.1g
  • Price$1580
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberG906
  • Product descriptionAbacavir
  • Packaging1g
  • Price$153
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA310646
  • Product description((1S,4R)-4-(2-Amino-6-(cyclopropylamino)-9H-purin-9-yl)cyclopent-2-en-1-yl)methanol 98+%
  • Packaging10mg
  • Price$5
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA310646
  • Product description((1S,4R)-4-(2-Amino-6-(cyclopropylamino)-9H-purin-9-yl)cyclopent-2-en-1-yl)methanol 98+%
  • Packaging50mg
  • Price$7
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA310646
  • Product description((1S,4R)-4-(2-Amino-6-(cyclopropylamino)-9H-purin-9-yl)cyclopent-2-en-1-yl)methanol 98+%
  • Packaging1g
  • Price$11
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA310646
  • Product description((1S,4R)-4-(2-Amino-6-(cyclopropylamino)-9H-purin-9-yl)cyclopent-2-en-1-yl)methanol 98+%
  • Packaging5g
  • Price$33
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA310646
  • Product description((1S,4R)-4-(2-Amino-6-(cyclopropylamino)-9H-purin-9-yl)cyclopent-2-en-1-yl)methanol 98+%
  • Packaging25g
  • Price$137
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA310646
  • Product description((1S,4R)-4-(2-Amino-6-(cyclopropylamino)-9H-purin-9-yl)cyclopent-2-en-1-yl)methanol 98+%
  • Packaging100g
  • Price$453
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0010038
  • Product descriptionABACAVIR 95.00%
  • Packaging1G
  • Price$202.65
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3139
  • Product descriptionAbacavir
  • Packaging10mg
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3139
  • Product descriptionAbacavir
  • Packaging10mM(in 1mL H2O)
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3139
  • Product descriptionAbacavir
  • Packaging50mg
  • Price$95
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS516385
  • Product description((1S,4R)-4-(2-Amino-6-(cyclopropylamino)-9H-purin-9-yl)cyclopent-2-en-1-yl)methanol ≥98%
  • Packaging1g
  • Price$13
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS516385
  • Product description((1S,4R)-4-(2-Amino-6-(cyclopropylamino)-9H-purin-9-yl)cyclopent-2-en-1-yl)methanol ≥98%
  • Packaging5g
  • Price$39
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2675B
  • Product descriptionAbacavir
  • Packaging10mg
  • Price$45
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2675B
  • Product descriptionAbacavir
  • Packaging100mg
  • Price$95
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AHH API-1167 Abacavir 98% 0.1g $1580 2021-12-16 Buy
AK Scientific G906 Abacavir 1g $153 2021-12-16 Buy
Ambeed A310646 ((1S,4R)-4-(2-Amino-6-(cyclopropylamino)-9H-purin-9-yl)cyclopent-2-en-1-yl)methanol 98+% 10mg $5 2021-12-16 Buy
Ambeed A310646 ((1S,4R)-4-(2-Amino-6-(cyclopropylamino)-9H-purin-9-yl)cyclopent-2-en-1-yl)methanol 98+% 50mg $7 2021-12-16 Buy
Ambeed A310646 ((1S,4R)-4-(2-Amino-6-(cyclopropylamino)-9H-purin-9-yl)cyclopent-2-en-1-yl)methanol 98+% 1g $11 2021-12-16 Buy
Ambeed A310646 ((1S,4R)-4-(2-Amino-6-(cyclopropylamino)-9H-purin-9-yl)cyclopent-2-en-1-yl)methanol 98+% 5g $33 2021-12-16 Buy
Ambeed A310646 ((1S,4R)-4-(2-Amino-6-(cyclopropylamino)-9H-purin-9-yl)cyclopent-2-en-1-yl)methanol 98+% 25g $137 2021-12-16 Buy
Ambeed A310646 ((1S,4R)-4-(2-Amino-6-(cyclopropylamino)-9H-purin-9-yl)cyclopent-2-en-1-yl)methanol 98+% 100g $453 2021-12-16 Buy
American Custom Chemicals Corporation API0010038 ABACAVIR 95.00% 1G $202.65 2021-12-16 Buy
ApexBio Technology A3139 Abacavir 10mg $50 2021-12-16 Buy
ApexBio Technology A3139 Abacavir 10mM(in 1mL H2O) $50 2021-12-16 Buy
ApexBio Technology A3139 Abacavir 50mg $95 2021-12-16 Buy
Arctom AS516385 ((1S,4R)-4-(2-Amino-6-(cyclopropylamino)-9H-purin-9-yl)cyclopent-2-en-1-yl)methanol ≥98% 1g $13 2021-12-16 Buy
Arctom AS516385 ((1S,4R)-4-(2-Amino-6-(cyclopropylamino)-9H-purin-9-yl)cyclopent-2-en-1-yl)methanol ≥98% 5g $39 2021-12-16 Buy
AvaChem 2675B Abacavir 10mg $45 2021-12-16 Buy
AvaChem 2675B Abacavir 100mg $95 2021-12-16 Buy

Properties

Melting point :165°
alpha :D20 -59.7°; 43620 -127.8°; 36520 -218.1° (c = 0.15 in methanol)
Boiling point :636.0±65.0 °C(Predicted)
Density :1.70±0.1 g/cm3(Predicted)
storage temp. :Sealed in dry,2-8°C
solubility :DMSO (Slightly, Heated), Methanol (Slightly)
pka :5.01(at 25℃)
form :Solid
color :Off-White to Pale Beige
Merck :14,1
BCS Class :3
CAS DataBase Reference :136470-78-5(CAS DataBase Reference)
EPA Substance Registry System :2-Cyclopentene-1-methanol, 4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]-, (1S,4R)- (136470-78-5)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H317 May cause an allergic skin reaction Sensitisation, Skin Category 1 Warning GHS hazard pictograms P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled Sensitisation, respiratory Category 1 Danger GHS hazard pictograms P261, P285, P304+P341, P342+P311,P501
H341 Suspected of causing genetic defects Germ cell mutagenicity Category 2 Warning P201,P202, P281, P308+P313, P405,P501
H361 Suspected of damaging fertility or the unborn child Reproductive toxicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P272 Contaminated work clothing should not be allowed out of the workplace.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P284 Wear respiratory protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P333+P313 IF SKIN irritation or rash occurs: Get medical advice/attention.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

The drug is extensively metabolized via stepwise phosphorylation to 5′-mono-, di-, and triphosphate. Abacavir is well absorbed (>75%) and penetrates the CNS. The drug can be taken without regard to meals. The drug does not show any clinically significant drug–drug interactions. Abacavir has been reported to produce life-threatening hypersensitivity reactions. The major use of abacavir appears to be in combination with other nucleoside RT inhibitors. A fixed-combination product has recently been approved by the U.S. FDA consisting of 300 mg of ABC, 150 mg of 3TC, and 300 mg of ZDV (Trizivar). The combination has been shown to be superior to other combinations in reducing viral load as well as to show improvement in CD4 cell count.

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