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ChemicalBook >> CAS DataBase List >> AC-IETD-AFC

AC-IETD-AFC

AC-IETD-AFC price.
  • $44 - $321
  • Product name: AC-IETD-AFC
  • CAS: 211990-57-7
  • MF: C31H38F3N5O12
  • MW: 729.65
  • EINECS:
  • MDL Number:MFCD02094703
  • Synonyms:CASPASE 8 SUBSTRATE 1F, FLUOROGENIC;CASPASE-8 FLUOROGENIC SUBSTRATE;GRANZYME B SUBSTRATE I, COLORIMETRIC;AC-IETD-AFC;AC-ILE-GLU-THR-ASP-7-AMINO-4-TRIFLUORO-METHYLCOUMARIN;AC-ILE-GLU-THR-ASP-AFC;N-ACETYL-ILE-GLU-THR-ASP-(7-AMINO-4-TRIFLUOROMETHYLCOUMARIN);N-ACETYL-ILE-GLU-THR-ASP-7-AMINO-4-TRIFLUOROMETHYLCOUMARIN AFC
5 prices
Selected condition：
Brand
  • Alfa Aesar
  • Cayman Chemical
  • TRC
Package
  • 1mg
  • 5mg
  • 10mg
  • ManufacturerAlfa Aesar
  • Product numberJ64258
  • Product descriptionN-Acetyl-Ile-Glu-Thr-Asp-7-amino-4-(trifluoromethyl)coumarin
  • Packaging5mg
  • Price$161
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number17480
  • Product descriptionAc-IETD-AFC ≥95%
  • Packaging1mg
  • Price$44
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number17480
  • Product descriptionAc-IETD-AFC ≥95%
  • Packaging5mg
  • Price$193
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number17480
  • Product descriptionAc-IETD-AFC ≥95%
  • Packaging10mg
  • Price$321
  • Updated2024-03-01
  • Buy
  • ManufacturerTRC
  • Product numberA795613
  • Product descriptionAc-IETD-AFC
  • Packaging5mg
  • Price$145
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Alfa Aesar J64258 N-Acetyl-Ile-Glu-Thr-Asp-7-amino-4-(trifluoromethyl)coumarin 5mg $161 2021-12-16 Buy
Cayman Chemical 17480 Ac-IETD-AFC ≥95% 1mg $44 2024-03-01 Buy
Cayman Chemical 17480 Ac-IETD-AFC ≥95% 5mg $193 2024-03-01 Buy
Cayman Chemical 17480 Ac-IETD-AFC ≥95% 10mg $321 2024-03-01 Buy
TRC A795613 Ac-IETD-AFC 5mg $145 2021-12-16 Buy

Properties

Boiling point :1113.8±65.0 °C(Predicted)
Density :1.437±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :Soluble in DMSO
pka :4.09±0.10(Predicted)
form :Lyophilized powder
color :White to off-white

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Ac-IETD-AFC is a fluorogenic substrate that can be cleaved by caspase-8 and related enzymes that recognize the amino acid sequence IETD, including caspase-3 processing enzyme, caspase-10, and granzyme B. Caspase activity can be quantified by fluorescent detection of free AFC (also known as 7-amino-4-trifluoromethylcoumarin), which is excited at 400 nm and emits at 505 nm.

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