(5S,12R)-5,12,20-TRIHYDROXY-(6Z,8E,10E,14Z)-EICOSATETRAENOIC ACID
- $165 - $5849.55
- Product name: (5S,12R)-5,12,20-TRIHYDROXY-(6Z,8E,10E,14Z)-EICOSATETRAENOIC ACID
- CAS: 79516-82-8
- MF: C20H32O5
- MW: 352.47
- EINECS:
- MDL Number:MFCD00065858
- Synonyms:hydroxyleukotriene B4;(5R,12S,6Z,8E,10E,14Z)-5,12,20-Trihydroxy-6,8,10,14-icosatetraenoic acid;20-OH-LTB4;20-HYDROXYLEUKOTRIENE B4;5S,12R,20-TRIHYDROXY-6Z,8E,10E,14Z-EICOSATETRAENOIC ACID;(5S,12R)-5,12,20-TRIHYDROXY-(6Z,8E,10E,14Z)-EICOSATETRAENOIC ACID;PTJFJXLGRSTECQ-PSPARDEHSA-N;6,8,10,14-Eicosatetraenoic acid, 5,12,20-trihydroxy-, (5S,6Z,8E,10E,12R,14Z)-
6 prices
Selected condition:
Brand
- AHH
- American Custom Chemicals Corporation
- Cayman Chemical
- TRC
Package
- 25μg
- 50μg
- 0.0001g
- 100μg
- 1MG
- ManufacturerAHH
- Product numberMT-15150
- Product description20-HydroxyleukotrieneB4 97%
- Packaging0.0001g
- Price$445
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberCCH0007226
- Product description(5S,12R)-5,12,20-TRIHYDROXY-(6Z,8E,10E,14Z)-EICOSATETRAENOIC ACID 95.00%
- Packaging1MG
- Price$5849.55
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number20190
- Product description20-hydroxy Leukotriene B4 ≥97%
- Packaging25μg
- Price$165
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number20190
- Product description20-hydroxy Leukotriene B4 ≥97%
- Packaging50μg
- Price$311
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number20190
- Product description20-hydroxy Leukotriene B4 ≥97%
- Packaging100μg
- Price$587
- Updated2024-03-01
- Buy
- ManufacturerTRC
- Product numberG377488
- Product description20-OH-LTB4
- Packaging1mg
- Price$1680
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AHH | MT-15150 | 20-HydroxyleukotrieneB4 97% | 0.0001g | $445 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | CCH0007226 | (5S,12R)-5,12,20-TRIHYDROXY-(6Z,8E,10E,14Z)-EICOSATETRAENOIC ACID 95.00% | 1MG | $5849.55 | 2021-12-16 | Buy |
Cayman Chemical | 20190 | 20-hydroxy Leukotriene B4 ≥97% | 25μg | $165 | 2024-03-01 | Buy |
Cayman Chemical | 20190 | 20-hydroxy Leukotriene B4 ≥97% | 50μg | $311 | 2024-03-01 | Buy |
Cayman Chemical | 20190 | 20-hydroxy Leukotriene B4 ≥97% | 100μg | $587 | 2024-03-01 | Buy |
TRC | G377488 | 20-OH-LTB4 | 1mg | $1680 | 2021-12-16 | Buy |
Properties
Boiling point :581.8±50.0 °C(Predicted)
Density :1.097±0.06 g/cm3(Predicted)
storage temp. :−20°C
solubility :DMF: 50 mg/ml; DMSO: 50 mg/ml; Ethanol: 50 mg/ml; PBS pH 7.2: 1 mg/ml
pka :4.66±0.10(Predicted)
form :Clear to light-yellow liquid.
Density :1.097±0.06 g/cm3(Predicted)
storage temp. :−20°C
solubility :DMF: 50 mg/ml; DMSO: 50 mg/ml; Ethanol: 50 mg/ml; PBS pH 7.2: 1 mg/ml
pka :4.66±0.10(Predicted)
form :Clear to light-yellow liquid.
Safety Information
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Signal word: | Danger | ||||||||||||||||||||||||||||||
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Description
20-hydroxy LTB4 is a metabolite of LTB4 in human neutrophils. In human leukocytes, LTB4 is inactivated by the enzyme LTB4 20-hydroxylase. 20-hydroxy LTB4 is not only much less active (~5%) compared to LTB4 in causing degranulation of PMNL, but actually inhibits LTB4-induced degranulation of human neutrophils (Ki = 13.3 nM). However, 20-hydroxy LTB4 is as active as LTB4 in contracting parenchymal strips from guinea pig lung. 20-hydroxy LTB4 retains considerable ligand binding affinity at the BLT2 receptor, but does not appear to function as an agonist.More related product prices
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$165-5849.55