7,8-Dihydroxyflavone
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- $5 - $1170.31
- Product name: 7,8-Dihydroxyflavone
- CAS: 38183-03-8
- MF: C15H10O4
- MW: 254.24
- EINECS:253-812-4
- MDL Number:MFCD00006836
- Synonyms:7,8-DIHYDROXYFLAVONE;DIHYDROXYFLAVONE, 7,8-(RG);7,8-dihydroxy-2-phenyl-4h-1-benzopyran-4-on ;TIMTEC-BB SBB000930;DIHYDROXYFLAVONE, 7,8-;7,8-Dihydroxy-2-phenyl-4H-chroMen-4-one;4H-1-Benzopyran-4-one,7,8-dihydroxy-2-phenyl-;2-Phenyl-7,8-dihydroxy-4H-1-benzopyran-4-one
49 prices
Selected condition：
Brand
- AHH
- AK Scientific
- Alfa Aesar
- Alichem
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Biosynth Carbosynth
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- CSNpharm
- DC Chemicals
- Sigma-Aldrich
- TCI Chemical
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- Usbiological
Package
- 20mg
- 10
- 25mg
- 250mg
- 500mg
- 2g
- 50
- 10mM(in 1mL DMSO)
- 10MG
- 50MG
- 100mg
- 1g
- 5g
- 10g
- 25g
- ManufacturerAHH
- Product numberMT-09849
- Product description7,8-Dihydroxyflavone 98%
- Packaging10g
- Price$502
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number4921AB
- Product description7,8-Dihydroxy-2-phenyl-4H-chromen-4-one
- Packaging100mg
- Price$109
- Updated2021-12-16
- Buy
- ManufacturerAlfa Aesar
- Product numberH27852
- Product description7,8-Dihydroxyflavone hydrate, 97%
- Packaging1g
- Price$106.65
- Updated2024-03-01
- Buy
- ManufacturerAlfa Aesar
- Product numberH27852
- Product description7,8-Dihydroxyflavone hydrate, 97%
- Packaging5g
- Price$315.65
- Updated2024-03-01
- Buy
- ManufacturerAlichem
- Product number38183038
- Product description7,8-Dihydroxyflavone
- Packaging5g
- Price$212
- Updated2021-12-16
- Buy
- ManufacturerAlichem
- Product number38183038
- Product description7,8-Dihydroxyflavone
- Packaging10g
- Price$367.5
- Updated2021-12-16
- Buy
- ManufacturerAlichem
- Product number38183038
- Product description7,8-Dihydroxyflavone
- Packaging25g
- Price$757.5
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberPXT0005380
- Product description7,8 DIHYDROXYFLAVONE 95.00%
- Packaging10MG
- Price$697.34
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberPXT0005380
- Product description7,8 DIHYDROXYFLAVONE 95.00%
- Packaging50MG
- Price$1170.31
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB5484
- Product description7,8-Dihydroxyflavone
- Packaging10mg
- Price$40
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB5484
- Product description7,8-Dihydroxyflavone
- Packaging10mM(in 1mL DMSO)
- Price$70
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB5484
- Product description7,8-Dihydroxyflavone
- Packaging50mg
- Price$80
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS533290
- Product description7,8-Dihydroxyflavone 97%
- Packaging25g
- Price$339
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS533290
- Product description7,8-Dihydroxyflavone 97%
- Packaging5g
- Price$108
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberCFN96512
- Product description7,8-Dihydroxyflavone
- Packaging20mg
- Price$70
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS533290
- Product description7,8-Dihydroxyflavone 97%
- Packaging1g
- Price$36
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AHH | MT-09849 | 7,8-Dihydroxyflavone 98% | 10g | $502 | 2021-12-16 | Buy |
| AK Scientific | 4921AB | 7,8-Dihydroxy-2-phenyl-4H-chromen-4-one | 100mg | $109 | 2021-12-16 | Buy |
| Alfa Aesar | H27852 | 7,8-Dihydroxyflavone hydrate, 97% | 1g | $106.65 | 2024-03-01 | Buy |
| Alfa Aesar | H27852 | 7,8-Dihydroxyflavone hydrate, 97% | 5g | $315.65 | 2024-03-01 | Buy |
| Alichem | 38183038 | 7,8-Dihydroxyflavone | 5g | $212 | 2021-12-16 | Buy |
| Alichem | 38183038 | 7,8-Dihydroxyflavone | 10g | $367.5 | 2021-12-16 | Buy |
| Alichem | 38183038 | 7,8-Dihydroxyflavone | 25g | $757.5 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | PXT0005380 | 7,8 DIHYDROXYFLAVONE 95.00% | 10MG | $697.34 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | PXT0005380 | 7,8 DIHYDROXYFLAVONE 95.00% | 50MG | $1170.31 | 2021-12-16 | Buy |
| ApexBio Technology | B5484 | 7,8-Dihydroxyflavone | 10mg | $40 | 2021-12-16 | Buy |
| ApexBio Technology | B5484 | 7,8-Dihydroxyflavone | 10mM(in 1mL DMSO) | $70 | 2021-12-16 | Buy |
| ApexBio Technology | B5484 | 7,8-Dihydroxyflavone | 50mg | $80 | 2021-12-16 | Buy |
| Arctom | AS533290 | 7,8-Dihydroxyflavone 97% | 25g | $339 | 2021-12-16 | Buy |
| Arctom | AS533290 | 7,8-Dihydroxyflavone 97% | 5g | $108 | 2021-12-16 | Buy |
| Arctom | CFN96512 | 7,8-Dihydroxyflavone | 20mg | $70 | 2021-12-16 | Buy |
| Arctom | AS533290 | 7,8-Dihydroxyflavone 97% | 1g | $36 | 2021-12-16 | Buy |
Properties
Melting point :243-246°C
Boiling point :494.4±45.0 °C(Predicted)
Density :1.443±0.06 g/cm3(Predicted)
FEMA :4830 | 7,8-DIHYDROXYFLAVONE
storage temp. :Inert atmosphere,Room Temperature
solubility :DMSO: soluble24mg/mL
form :solid
pka :6.86±0.40(Predicted)
color :Yellow or tan
Stability :Stable for 1 year from date of purchase as supplied. Protect from moisture. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 week.
InChI :InChI=1S/C15H10O4/c16-11-7-6-10-12(17)8-13(19-15(10)14(11)18)9-4-2-1-3-5-9/h1-8,16,18H
InChIKey :COCYGNDCWFKTMF-UHFFFAOYSA-N
SMILES :C1(C2=CC=CC=C2)OC2=C(O)C(O)=CC=C2C(=O)C=1
LogP :2.760 (est)
CAS DataBase Reference :38183-03-8(CAS DataBase Reference)
Boiling point :494.4±45.0 °C(Predicted)
Density :1.443±0.06 g/cm3(Predicted)
FEMA :4830 | 7,8-DIHYDROXYFLAVONE
storage temp. :Inert atmosphere,Room Temperature
solubility :DMSO: soluble24mg/mL
form :solid
pka :6.86±0.40(Predicted)
color :Yellow or tan
Stability :Stable for 1 year from date of purchase as supplied. Protect from moisture. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 week.
InChI :InChI=1S/C15H10O4/c16-11-7-6-10-12(17)8-13(19-15(10)14(11)18)9-4-2-1-3-5-9/h1-8,16,18H
InChIKey :COCYGNDCWFKTMF-UHFFFAOYSA-N
SMILES :C1(C2=CC=CC=C2)OC2=C(O)C(O)=CC=C2C(=O)C=1
LogP :2.760 (est)
CAS DataBase Reference :38183-03-8(CAS DataBase Reference)
Safety Information
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| Signal word: | Warning | ||||||||||||||||||||||||||||
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Description
7,8-Dihydroxyflavone (7,8-DHF) is a monophenolic flavone with diverse effects. It acts as an agonist of the neurotrophic tyrosine kinase receptor TrkB (Kd = 320 nM), protecting neurons that express TrkB from apoptosis. 7,8-DHF is neuroprotective in an animal model of Parkinson’s disease. It supports emotional learning in mice and reverses memory deficits in a mouse model of Alzheimer’s disease. It also improves motor function and extends survival in an animal model of Huntington’s disease. 7,8-DHF inhibits the cytochrome P450 aromatase (IC50 = 10 μM) and, in this way, alters estrogen metabolism. It also has antioxidant action that increases intracellular glutathione synthesis and scavenges reactive oxygen species.Related product price
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Suppliers and manufacturers
Tianjin Kilo Pharmaceutical Sci-Tech Co., Ltd
