[2-(4-chlorophenyl)quinolin-4-yl]-(2-piperidyl)methanol
![[2-(4-chlorophenyl)quinolin-4-yl]-(2-piperidyl)methanol price.](/CAS/GIF/5428-80-8.gif)
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- $51 - $1450
- Product name: [2-(4-chlorophenyl)quinolin-4-yl]-(2-piperidyl)methanol
- CAS: 5428-80-8
- MF: C21H21ClN2O
- MW: 352.86
- EINECS:
- MDL Number:MFCD29918839
- Synonyms:[2-(4-chlorophenyl)quinolin-4-yl]-(2-piperidyl)methanol;4-Quinolinemethanol,2-(4-chlorophenyl)-a-2-piperidinyl-;NSC 13316;NSC 13316;NSC13316;NSC-13316;VACQUINOL 1;VACQUINOL1;NSC13316;NSC-13316;CS-2185;4-Quinolinemethanol, 2-(4-chlorophenyl)-α-2-piperidinyl-
14 prices
Brand
- AK Scientific
- ApexBio Technology
- Apolloscientific
- Cayman Chemical
- DC Chemicals
- TRC
- Usbiological
Package
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- ManufacturerAK Scientific
- Product number5589BA
- Product description(2-(4-Chlorophenyl)quinolin-4-yl)(piperidin-2-yl)methanol
- Packaging5mg
- Price$357
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB6159
- Product descriptionVacquinol-1
- Packaging5mg
- Price$146
- Updated2021-12-16
- Buy
- ManufacturerApolloscientific
- Product numberBISN0246
- Product description(2-(4-Chlorophenyl)quinolin-4-yl)(piperidin-2-yl)methanol
- Packaging5mg
- Price$131
- Updated2021-12-16
- Buy
- ManufacturerApolloscientific
- Product numberBISN0246
- Product description(2-(4-Chlorophenyl)quinolin-4-yl)(piperidin-2-yl)methanol
- Packaging10mg
- Price$167
- Updated2021-12-16
- Buy
- ManufacturerApolloscientific
- Product numberBISN0246
- Product description(2-(4-Chlorophenyl)quinolin-4-yl)(piperidin-2-yl)methanol
- Packaging25mg
- Price$283
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number16321
- Product descriptionVacquinol-1 ≥98%
- Packaging1mg
- Price$51
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16321
- Product descriptionVacquinol-1 ≥98%
- Packaging5mg
- Price$140
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16321
- Product descriptionVacquinol-1 ≥98%
- Packaging10mg
- Price$253
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16321
- Product descriptionVacquinol-1 ≥98%
- Packaging25mg
- Price$569
- Updated2024-03-01
- Buy
- ManufacturerDC Chemicals
- Product numberDC8473
- Product descriptionVacquinol-1 >98%
- Packaging50mg
- Price$450
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC8473
- Product descriptionVacquinol-1 >98%
- Packaging100mg
- Price$800
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC8473
- Product descriptionVacquinol-1 >98%
- Packaging250mg
- Price$1450
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberV075000
- Product descriptionVacquinol-1
- Packaging1mg
- Price$55
- Updated2021-12-16
- Buy
- ManufacturerUsbiological
- Product number468532
- Product descriptionVacquinol-1
- Packaging1mg
- Price$319
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 5589BA | (2-(4-Chlorophenyl)quinolin-4-yl)(piperidin-2-yl)methanol | 5mg | $357 | 2021-12-16 | Buy |
| ApexBio Technology | B6159 | Vacquinol-1 | 5mg | $146 | 2021-12-16 | Buy |
| Apolloscientific | BISN0246 | (2-(4-Chlorophenyl)quinolin-4-yl)(piperidin-2-yl)methanol | 5mg | $131 | 2021-12-16 | Buy |
| Apolloscientific | BISN0246 | (2-(4-Chlorophenyl)quinolin-4-yl)(piperidin-2-yl)methanol | 10mg | $167 | 2021-12-16 | Buy |
| Apolloscientific | BISN0246 | (2-(4-Chlorophenyl)quinolin-4-yl)(piperidin-2-yl)methanol | 25mg | $283 | 2021-12-16 | Buy |
| Cayman Chemical | 16321 | Vacquinol-1 ≥98% | 1mg | $51 | 2024-03-01 | Buy |
| Cayman Chemical | 16321 | Vacquinol-1 ≥98% | 5mg | $140 | 2024-03-01 | Buy |
| Cayman Chemical | 16321 | Vacquinol-1 ≥98% | 10mg | $253 | 2024-03-01 | Buy |
| Cayman Chemical | 16321 | Vacquinol-1 ≥98% | 25mg | $569 | 2024-03-01 | Buy |
| DC Chemicals | DC8473 | Vacquinol-1 >98% | 50mg | $450 | 2021-12-16 | Buy |
| DC Chemicals | DC8473 | Vacquinol-1 >98% | 100mg | $800 | 2021-12-16 | Buy |
| DC Chemicals | DC8473 | Vacquinol-1 >98% | 250mg | $1450 | 2021-12-16 | Buy |
| TRC | V075000 | Vacquinol-1 | 1mg | $55 | 2021-12-16 | Buy |
| Usbiological | 468532 | Vacquinol-1 | 1mg | $319 | 2021-12-16 | Buy |
Properties
Melting point :198-199.5 °C
Boiling point :551.4±50.0 °C(Predicted)
Density :1.244±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 10 mg/ml; DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml; DMSO: 1 mg/ml; Ethanol: 0.25 mg/ml
form :A crystalline solid
pka :13.22±0.20(Predicted)
color :white to beige
Boiling point :551.4±50.0 °C(Predicted)
Density :1.244±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 10 mg/ml; DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml; DMSO: 1 mg/ml; Ethanol: 0.25 mg/ml
form :A crystalline solid
pka :13.22±0.20(Predicted)
color :white to beige
Safety Information
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| Signal word: | Warning | |||||||||||||||||||||
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Description
Vacquinols are a new class of quinine-derivatives that stimulate death in glioblastoma cells by massive macropinocytotic vacuolization, ATP depletion, and cytoplasmic membrane rupture. A key effector of vacquinols is MAPK kinase 4 (MKK4). Vacquinol-1 is an activator of MKK4-dependent macropinocytotic cell death in glioblastoma cells. It induces ATP depletion in glioblastoma cells (IC50 = 3.14 μM at 1 day) without affecting fibroblasts, embryonic stem cells, or osteosarcoma cells. Vacquinol-1 is orally bioavailable with good brain penetrance and excellent pharmacokinetics. Oral administration of vacquinol-1 (20 mg/kg once daily for five days) substantially impairs the growth of engrafted glioblastoma cell tumors in mice and prolongs survival.Related product price
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Suppliers and manufacturers
ATK CHEMICAL COMPANY LIMITED
Zhejiang J&C Biological Technology Co.,Limited
InvivoChem
TargetMol Chemicals Inc.
ShenZhen Trendseen Biological Technology Co.,Ltd.
Wuhan Topule Biopharmaceutical Co., Ltd
Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd
Shanghai Acmec Biochemical Technology Co., Ltd.
