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ChemicalBook >> CAS DataBase List >> 3-Cyano-4-phenyl-6-(3-bromo-6-hydroxy)phenyl-2(1H)-pyridone

3-Cyano-4-phenyl-6-(3-bromo-6-hydroxy)phenyl-2(1H)-pyridone

3-Cyano-4-phenyl-6-(3-bromo-6-hydroxy)phenyl-2(1H)-pyridone price.
  • $27 - $2097.8
  • Product name: 3-Cyano-4-phenyl-6-(3-bromo-6-hydroxy)phenyl-2(1H)-pyridone
  • CAS: 491871-58-0
  • MF: C18H11BrN2O2
  • MW: 367.2
  • EINECS:
  • MDL Number:MFCD00276275
  • Synonyms:3-Cyano-4-phenyl-6-(3-bromo-6-hydroxy)phenyl-2(1H)-pyridone;TCS PIM-1 1;SC 204330;6-(5-Bromo-2-hydroxyphenyl)-1,2-dihydro-2-oxo-4-phenyl-3-pyridinecarbonitrile;TCS PIM-1;TCS PIM-1 1, >=98%;SC 204330; TCS PIM 1-1;CS-1482
27 prices
Selected condition：
Brand
  • AK Scientific
  • Ambeed
  • ApexBio Technology
  • Biorbyt Ltd
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Tocris
  • TRC
  • Usbiological
Package
  • 1mg
  • 50
  • 5mg
  • 10
  • 10mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • 10mM(in 1mL DMSO)
  • 1000mg
  • ManufacturerAK Scientific
  • Product numberJ57518
  • Product descriptionTCSPIM-11
  • Packaging5mg
  • Price$62
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberSYN5483
  • Product descriptionTCSPIM-11
  • Packaging100mg
  • Price$931
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA118376
  • Product descriptionTCSPIM-11 98+%
  • Packaging1mg
  • Price$27
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA118376
  • Product descriptionTCSPIM-11 98+%
  • Packaging5mg
  • Price$46
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA118376
  • Product descriptionTCSPIM-11 98+%
  • Packaging10mg
  • Price$60
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA118376
  • Product descriptionTCSPIM-11 98+%
  • Packaging50mg
  • Price$102
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA118376
  • Product descriptionTCSPIM-11 98+%
  • Packaging1g
  • Price$657
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4521
  • Product descriptionTCSPIM-11
  • Packaging10mg
  • Price$108
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4521
  • Product descriptionTCSPIM-11
  • Packaging10mM(in 1mL DMSO)
  • Price$119
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181333
  • Product descriptionTCS PIM-1 1 >98%
  • Packaging1000mg
  • Price$2097.8
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181333
  • Product descriptionTCS PIM-1 1 >98%
  • Packaging250mg
  • Price$1060.8
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181333
  • Product descriptionTCS PIM-1 1 >98%
  • Packaging100mg
  • Price$542.3
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number16286
  • Product descriptionTCS PIM-1 1 ≥98%
  • Packaging5mg
  • Price$97
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number16286
  • Product descriptionTCS PIM-1 1 ≥98%
  • Packaging10mg
  • Price$155
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number16286
  • Product descriptionTCS PIM-1 1 ≥98%
  • Packaging50mg
  • Price$360
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number16286
  • Product descriptionTCS PIM-1 1 ≥98%
  • Packaging100mg
  • Price$672
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific J57518 TCSPIM-11 5mg $62 2021-12-16 Buy
AK Scientific SYN5483 TCSPIM-11 100mg $931 2021-12-16 Buy
Ambeed A118376 TCSPIM-11 98+% 1mg $27 2021-12-16 Buy
Ambeed A118376 TCSPIM-11 98+% 5mg $46 2021-12-16 Buy
Ambeed A118376 TCSPIM-11 98+% 10mg $60 2021-12-16 Buy
Ambeed A118376 TCSPIM-11 98+% 50mg $102 2021-12-16 Buy
Ambeed A118376 TCSPIM-11 98+% 1g $657 2021-12-16 Buy
ApexBio Technology A4521 TCSPIM-11 10mg $108 2021-12-16 Buy
ApexBio Technology A4521 TCSPIM-11 10mM(in 1mL DMSO) $119 2021-12-16 Buy
Biorbyt Ltd orb181333 TCS PIM-1 1 >98% 1000mg $2097.8 2021-12-16 Buy
Biorbyt Ltd orb181333 TCS PIM-1 1 >98% 250mg $1060.8 2021-12-16 Buy
Biorbyt Ltd orb181333 TCS PIM-1 1 >98% 100mg $542.3 2021-12-16 Buy
Cayman Chemical 16286 TCS PIM-1 1 ≥98% 5mg $97 2024-03-01 Buy
Cayman Chemical 16286 TCS PIM-1 1 ≥98% 10mg $155 2024-03-01 Buy
Cayman Chemical 16286 TCS PIM-1 1 ≥98% 50mg $360 2024-03-01 Buy
Cayman Chemical 16286 TCS PIM-1 1 ≥98% 100mg $672 2024-03-01 Buy

Properties

Boiling point :592.6±50.0 °C(Predicted)
Density :1.63±0.1 g/cm3(Predicted)
storage temp. :Store at +4°C
solubility :insoluble in H2O; insoluble in EtOH; ≥12.8 mg/mL in DMSO
form :solid
pka :6.93±0.10(Predicted)
color :Light yellow to yellow

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

The proto-oncogene serine/threonine-protein kinases, Pim-1 and Pim-2, are enzymes involved in cytokine signaling and participate in various signal transduction pathways, including cell growth, differentiation, and apoptosis. Their overexpression has been implicated in prostate cancer, some forms of leukemia, and lymphoma. TCS PIM-1 1 is an ATP-competitive Pim-1 kinase inhibitor (IC50 = 50 nM) that displays selectivity over the related kinases, Pim-2 and MEK1/2 (IC50s = >20 μM).

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