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ChemicalBook >> CAS DataBase List >> Chloramphenicol hemisuccinate

Chloramphenicol hemisuccinate

Chloramphenicol hemisuccinate price.
  • $65 - $580
  • Product name: Chloramphenicol hemisuccinate
  • CAS: 3544-94-3
  • MF: C15H16Cl2N2O8
  • MW: 423.2
  • EINECS:222-590-0
  • MDL Number:MFCD01683261
  • Synonyms:[2-[(dichloroacetyl)amino]-3-hydroxy-3-(4-nitrophenyl)propyl] hydrogen [R-(R*,R*)]-succinate;Butanedioic acid hydrogen 1-[(2R,3R)-2-[(dichloroacetyl)amino]-3-hydroxy-3-(4-nitrophenyl)propyl] ester;Chloramphenicol 3-succinate;Succinic acid hydrogen 1-[(2R,3R)-3-(4-nitrophenyl)-2-(dichloroacetylamino)-3-hydroxypropan-1-yl] ester;ChloraMphenicol succinate, KeMicetine;Chloramphenicol succinate;Acetamide, 2,2-dichloro-N-[β-hydroxy-α-(hydroxymethyl)-p-nitrophenethyl]-, α-(hydrogen succinate), D-(-)-threo- (8CI);Butanedioic acid, mono[(2R,3R)-2-[(dichloroacetyl)amino]-3-hydroxy-3-(4-nitrophenyl)propyl] ester
5 prices
Selected condition：
Brand
  • AK Scientific
  • Cayman Chemical
  • TRC
Package
  • 5mg
  • 10mg
  • 25mg
  • ManufacturerAK Scientific
  • Product number0086BA
  • Product description4-[2-[(Dichloroacetyl)amino]-3-hydroxy-3-(4-nitrophenyl)propoxy]-4-oxobutanoicacid
  • Packaging25mg
  • Price$580
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number25453
  • Product descriptionChloramphenicol Succinate ≥99%
  • Packaging5mg
  • Price$97
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number25453
  • Product descriptionChloramphenicol Succinate ≥99%
  • Packaging25mg
  • Price$433
  • Updated2024-03-01
  • Buy
  • ManufacturerTRC
  • Product numberC325123
  • Product descriptionChloramphenicolSuccinate
  • Packaging5mg
  • Price$65
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberC325123
  • Product descriptionChloramphenicolSuccinate
  • Packaging10mg
  • Price$105
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 0086BA 4-[2-[(Dichloroacetyl)amino]-3-hydroxy-3-(4-nitrophenyl)propoxy]-4-oxobutanoicacid 25mg $580 2021-12-16 Buy
Cayman Chemical 25453 Chloramphenicol Succinate ≥99% 5mg $97 2024-03-01 Buy
Cayman Chemical 25453 Chloramphenicol Succinate ≥99% 25mg $433 2024-03-01 Buy
TRC C325123 ChloramphenicolSuccinate 5mg $65 2021-12-16 Buy
TRC C325123 ChloramphenicolSuccinate 10mg $105 2021-12-16 Buy

Properties

Melting point :127 °C
Boiling point :716.3±60.0 °C(Predicted)
Density :1.6769 (rough estimate)
refractive index :1.7350 (estimate)
storage temp. :Store at -20°C
solubility :DMF: soluble; DMSO: soluble; Ethanol: soluble; Methanol: soluble
form :A solid
pka :4.36±0.17(Predicted)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H332 Harmful if inhaled Acute toxicity,inhalation Category 4 Warning GHS hazard pictograms P261, P271, P304+P340, P312
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312 Call a POISON CENTER or doctor/physician if you feel unwell.
P321 Specific treatment (see … on this label).
P330 Rinse mouth.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P362 Take off contaminated clothing and wash before reuse.
P501 Dispose of contents/container to..…

Description

Chloramphenicol succinate is a water-soluble prodrug form of the antibiotic chloramphenicol. It is a substrate for succinate dehydrogenase (SDH) and is oxidized by human liver and rat liver and kidney mitochondria to release chloramphenicol in vitro. Chloramphenicol succinate reduces human leukocyte migration in vitro. In vivo, chloramphenicol succinate reduces E. coli growth in rabbit and rat models of pyelonephritis when administered at doses of 150 and 200 mg/kg, respectively. Chloramphenicol succinate (20 mg/kg) reduces infarct size in a porcine model of myocardial ischemia-reperfusion injury. Formulations containing chloramphenicol succinate have been used in the treatment of severe bacterial infections.

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