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ChemicalBook >> CAS DataBase List >> D-α-Tocopherol succinate

D-α-Tocopherol succinate

D-α-Tocopherol succinate price.
  • $13 - $704.55
  • Product name: D-α-Tocopherol succinate
  • CAS: 4345-03-3
  • MF: C33H54O5
  • MW: 530.78
  • EINECS:224-403-8
  • MDL Number:MFCD00072055
  • Synonyms:1210IU D-α-Tocopherol succinate,vitamin E succinate 1185IU D-α-Tocopherol succinate,vitamin E succinate;(+)-α-TOCOPHEROL ACID SUCCINATE;D-α-Tocopheryl succinate, Ph. Eur.;[2theta-[2theta(4theta,8theta)]]-cyl)-2h-1-benzopyran-6-yl]este ;alpha-tocopherol,succinate ;alpha-tocopherolhemisuccinate ;butanedioicacid,mono(3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltride ;butanedioicacid,mono[3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltride
23 prices
Selected condition:
Brand
  • AHH
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • Chem-Impex
  • Sigma-Aldrich
  • TCI Chemical
  • TRC
Package
  • 5MG
  • 100MG
  • 250MG
  • 500MG
  • 1g
  • 5g
  • 25g
  • 50g
  • 100g
  • T1610000
  • 500g
  • 1000g
  • ManufacturerAHH
  • Product numberMT-60430
  • Product descriptionVitaminEsuccinate 98%
  • Packaging1000g
  • Price$310
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberF717
  • Product descriptionD-alpha-Tocopherolsuccinate
  • Packaging1g
  • Price$19
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberF717
  • Product descriptionD-alpha-Tocopherolsuccinate
  • Packaging5g
  • Price$39
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberF717
  • Product descriptionD-alpha-Tocopherolsuccinate
  • Packaging25g
  • Price$122
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA324405
  • Product description4-Oxo-4-(((R)-2,5,7,8-tetramethyl-2-((4R,8R)-4,8,12-trimethyltridecyl)chroman-6-yl)oxy)butanoicacid 98%
  • Packaging25g
  • Price$13
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA324405
  • Product description4-Oxo-4-(((R)-2,5,7,8-tetramethyl-2-((4R,8R)-4,8,12-trimethyltridecyl)chroman-6-yl)oxy)butanoicacid 98%
  • Packaging100g
  • Price$40
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA324405
  • Product description4-Oxo-4-(((R)-2,5,7,8-tetramethyl-2-((4R,8R)-4,8,12-trimethyltridecyl)chroman-6-yl)oxy)butanoicacid 98%
  • Packaging500g
  • Price$150
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberVIT0000804
  • Product descriptionVITAMIN E SUCCINATE 95.00%
  • Packaging5MG
  • Price$451.7
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberVIT0000804
  • Product descriptionVITAMIN E SUCCINATE 95.00%
  • Packaging1G
  • Price$704.55
  • Updated2021-12-16
  • Buy
  • ManufacturerChem-Impex
  • Product number39266
  • Product descriptionD-α-Tocopherolsuccinate,97%(Assaybytitration,GC) 97%(Assaybytitration,GC)
  • Packaging5G
  • Price$41.44
  • Updated2021-12-16
  • Buy
  • ManufacturerChem-Impex
  • Product number39266
  • Product descriptionD-α-Tocopherolsuccinate,97%(Assaybytitration,GC) 97%(Assaybytitration,GC)
  • Packaging25G
  • Price$129.92
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberT3126
  • Product descriptionD-α-Tocopherol succinate semisynthetic, 1210?IU/g
  • Packaging5G
  • Price$34.32
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number47782
  • Product descriptionD-α-Tocopherol succinate analytical standard
  • Packaging100MG
  • Price$36
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberT3126
  • Product descriptionD-α-Tocopherol succinate semisynthetic, 1210?IU/g
  • Packaging25G
  • Price$58.4
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberPHR1029
  • Product descriptionTocopheryl Acid Succinate, a Pharmaceutical Secondary Standard; Certified Reference Material
  • Packaging500MG
  • Price$82.3
  • Updated2022-05-15
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberT1610000
  • Product descriptionRRR-α-Tocopheryl hydrogen succinate European Pharmacopoeia (EP) Reference Standard
  • PackagingT1610000
  • Price$152
  • Updated2023-06-20
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AHH MT-60430 VitaminEsuccinate 98% 1000g $310 2021-12-16 Buy
AK Scientific F717 D-alpha-Tocopherolsuccinate 1g $19 2021-12-16 Buy
AK Scientific F717 D-alpha-Tocopherolsuccinate 5g $39 2021-12-16 Buy
AK Scientific F717 D-alpha-Tocopherolsuccinate 25g $122 2021-12-16 Buy
Ambeed A324405 4-Oxo-4-(((R)-2,5,7,8-tetramethyl-2-((4R,8R)-4,8,12-trimethyltridecyl)chroman-6-yl)oxy)butanoicacid 98% 25g $13 2021-12-16 Buy
Ambeed A324405 4-Oxo-4-(((R)-2,5,7,8-tetramethyl-2-((4R,8R)-4,8,12-trimethyltridecyl)chroman-6-yl)oxy)butanoicacid 98% 100g $40 2021-12-16 Buy
Ambeed A324405 4-Oxo-4-(((R)-2,5,7,8-tetramethyl-2-((4R,8R)-4,8,12-trimethyltridecyl)chroman-6-yl)oxy)butanoicacid 98% 500g $150 2021-12-16 Buy
American Custom Chemicals Corporation VIT0000804 VITAMIN E SUCCINATE 95.00% 5MG $451.7 2021-12-16 Buy
American Custom Chemicals Corporation VIT0000804 VITAMIN E SUCCINATE 95.00% 1G $704.55 2021-12-16 Buy
Chem-Impex 39266 D-α-Tocopherolsuccinate,97%(Assaybytitration,GC) 97%(Assaybytitration,GC) 5G $41.44 2021-12-16 Buy
Chem-Impex 39266 D-α-Tocopherolsuccinate,97%(Assaybytitration,GC) 97%(Assaybytitration,GC) 25G $129.92 2021-12-16 Buy
Sigma-Aldrich T3126 D-α-Tocopherol succinate semisynthetic, 1210?IU/g 5G $34.32 2024-03-01 Buy
Sigma-Aldrich 47782 D-α-Tocopherol succinate analytical standard 100MG $36 2024-03-01 Buy
Sigma-Aldrich T3126 D-α-Tocopherol succinate semisynthetic, 1210?IU/g 25G $58.4 2024-03-01 Buy
Sigma-Aldrich PHR1029 Tocopheryl Acid Succinate, a Pharmaceutical Secondary Standard; Certified Reference Material 500MG $82.3 2022-05-15 Buy
Sigma-Aldrich T1610000 RRR-α-Tocopheryl hydrogen succinate European Pharmacopoeia (EP) Reference Standard T1610000 $152 2023-06-20 Buy

Properties

Melting point :~76 °C(lit.)
Boiling point :625.8±55.0 °C(Predicted)
Density :1.002±0.06 g/cm3(Predicted)
vapor pressure :0Pa at 20℃
storage temp. :-20°C
solubility :Practically insoluble in water, very soluble in methylene chloride, soluble in acetone and in anhydrous ethanol.
form :Solid
pka :4.35±0.17(Predicted)
color :White or off-white
Odor :Little or no odor
λmax :286nm(EtOH)(lit.)
Merck :14,9495
BRN :4038233
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
LogP :12 at 25℃
CAS DataBase Reference :4345-03-3(CAS DataBase Reference)
EPA Substance Registry System :D-.alpha.-Tocopheryl acid succinate (4345-03-3)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

D-α-Tocopheryl Succinate is a potent antioxidant tocopherol. At high concentrations it has been shown to trigger caspase-mediated apoptosis of certain cells and, at low concentrations, inhibit proliferation. Mechanistic studies suggest that this compound down-regulates the fibroblast growth factor receptor-1 (FGFR1). Other experiments report that D-α-Tocopheryl Succinate also targets ASK 1, GADD 45β, and MEK-4, three key components of stress-activated mitogen-activated protein kinase pathway.

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