2-Acetylphenothiazine
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- $21 - $2632.89
- Product name: 2-Acetylphenothiazine
- CAS: 6631-94-3
- MF: C14H11NOS
- MW: 241.31
- EINECS:229-626-4
- MDL Number:MFCD00005017
- Synonyms:2-ACETYLPHENOTHIAZINE;methyl phenothiazin-2-yl ketone;2-Acetyl-10H-phenothiazine;2-Acetylphenothiazin;1-(10H-Phenothiazin-2-yl)ethan-1- one, 2-Ethanoyl-10H-phenothiazine;ML 171;LABOTEST-BB LT00012652;NOX1 Inhibitor, ML171
35 prices
Selected condition：
Brand
- AHH
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Biosynth Carbosynth
- Cayman Chemical
- Chem-Impex
- ChemScene
- Crysdot
- CSNpharm
- Medical Isotopes, Inc.
- Sigma-Aldrich
- SynQuest Laboratories
- TCI Chemical
- TRC
- Usbiological
Package
- 10mg
- 50mg
- 100mg
- 250mg
- 500mg
- 1g
- 5G
- 10g
- 25g
- 50g
- 100g
- 500g
- 10mM(in 1mL DMSO)
- ManufacturerAHH
- Product numberMT-32712
- Product description2-Acetylphenothiazine 95%
- Packaging500g
- Price$460
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberL150
- Product description2-Acetylphenothiazine
- Packaging1g
- Price$21
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberL150
- Product description2-Acetylphenothiazine
- Packaging25g
- Price$145
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberL150
- Product description2-Acetylphenothiazine
- Packaging100g
- Price$241
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberCHM0020110
- Product description2-ACETYLPHENOTHIAZINE 95.00%
- Packaging25G
- Price$1156.6
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberCHM0020110
- Product description2-ACETYLPHENOTHIAZINE 95.00%
- Packaging100G
- Price$2632.89
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB5672
- Product descriptionML171
- Packaging50mg
- Price$40
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB5672
- Product descriptionML171
- Packaging10mM(in 1mL DMSO)
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFA01622
- Product description2-Acetylphenothiazine
- Packaging50mg
- Price$85
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFA01622
- Product description2-Acetylphenothiazine
- Packaging100mg
- Price$150
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFA01622
- Product description2-Acetylphenothiazine
- Packaging250mg
- Price$225
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFA01622
- Product description2-Acetylphenothiazine
- Packaging500mg
- Price$375
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFA01622
- Product description2-Acetylphenothiazine
- Packaging1g
- Price$600
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number19056
- Product description2-Acetylphenothiazine ≥98%
- Packaging10g
- Price$32
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number19056
- Product description2-Acetylphenothiazine ≥98%
- Packaging25g
- Price$70
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number19056
- Product description2-Acetylphenothiazine ≥98%
- Packaging50g
- Price$131
- Updated2024-03-01
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AHH | MT-32712 | 2-Acetylphenothiazine 95% | 500g | $460 | 2021-12-16 | Buy |
| AK Scientific | L150 | 2-Acetylphenothiazine | 1g | $21 | 2021-12-16 | Buy |
| AK Scientific | L150 | 2-Acetylphenothiazine | 25g | $145 | 2021-12-16 | Buy |
| AK Scientific | L150 | 2-Acetylphenothiazine | 100g | $241 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | CHM0020110 | 2-ACETYLPHENOTHIAZINE 95.00% | 25G | $1156.6 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | CHM0020110 | 2-ACETYLPHENOTHIAZINE 95.00% | 100G | $2632.89 | 2021-12-16 | Buy |
| ApexBio Technology | B5672 | ML171 | 50mg | $40 | 2021-12-16 | Buy |
| ApexBio Technology | B5672 | ML171 | 10mM(in 1mL DMSO) | $50 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FA01622 | 2-Acetylphenothiazine | 50mg | $85 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FA01622 | 2-Acetylphenothiazine | 100mg | $150 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FA01622 | 2-Acetylphenothiazine | 250mg | $225 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FA01622 | 2-Acetylphenothiazine | 500mg | $375 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FA01622 | 2-Acetylphenothiazine | 1g | $600 | 2021-12-16 | Buy |
| Cayman Chemical | 19056 | 2-Acetylphenothiazine ≥98% | 10g | $32 | 2024-03-01 | Buy |
| Cayman Chemical | 19056 | 2-Acetylphenothiazine ≥98% | 25g | $70 | 2024-03-01 | Buy |
| Cayman Chemical | 19056 | 2-Acetylphenothiazine ≥98% | 50g | $131 | 2024-03-01 | Buy |
Properties
Melting point :180-185 °C (lit.)
Boiling point :455.7±34.0 °C(Predicted)
Density :1.249±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,2-8°C
solubility :DMSO (Slightly), Methanol (Slightly, Heated)
pka :-2.45±0.20(Predicted)
form :Dark yellow-orange powder
color :Yellow to Dark Orange
λmax :244nm(MeOH)(lit.)
CAS DataBase Reference :6631-94-3(CAS DataBase Reference)
Boiling point :455.7±34.0 °C(Predicted)
Density :1.249±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,2-8°C
solubility :DMSO (Slightly), Methanol (Slightly, Heated)
pka :-2.45±0.20(Predicted)
form :Dark yellow-orange powder
color :Yellow to Dark Orange
λmax :244nm(MeOH)(lit.)
CAS DataBase Reference :6631-94-3(CAS DataBase Reference)
Safety Information
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| Signal word: | Warning | |||||||||||||||||||||
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Description
2-Acetylphenothiazine (2-APT) is a selective, cell-active inhibitor of NADPH oxidase 1 (NOX1) that blocks the generation of reactive oxygen species (ROS) in HT-29 cells with an IC50 value of 0.129 μM. It does not affect xanthine oxidase-dependent or mitochondrial ROS generation. 2-APT prevents ROS-dependent formation of ECM-degrading invadopodia in colon cancer cells. It also abolishes collagen-induced superoxide production by platelets (IC50 = 306 nM), preventing platelet aggregation and thrombus formation. 2-APT protects beta cells from cytokine-induced apoptosis by inhibiting NOX1. 2-APT can also activate the human transient receptor potential ankyrin 1 (TRPA1) nociceptor at 1-30 μM.Related product price
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Suppliers and manufacturers
Shanghai Daken Advanced Materials Co.,Ltd
Hubei Jusheng Technology Co.,Ltd.
Alchem Pharmtech,Inc.
CONIER CHEM AND PHARMA LIMITED
Shaanxi Dideu Medichem Co. Ltd
Hefei TNJ Chemical Industry Co.,Ltd.
Baoji Guokang Healthchem co.,ltd
Dayang Chem (Hangzhou) Co.,Ltd.
Labnetwork lnc.
