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ChemicalBook >> CAS DataBase List >> 4,4'-Bis(4-aminophenoxy)biphenyl

4,4'-Bis(4-aminophenoxy)biphenyl

4,4'-Bis(4-aminophenoxy)biphenyl price.
  • $5 - $1204.99
  • Product name: 4,4'-Bis(4-aminophenoxy)biphenyl
  • CAS: 13080-85-8
  • MF: C24H20N2O2
  • MW: 368.43
  • EINECS:627-298-0
  • MDL Number:MFCD00039151
  • Synonyms:4,4'-(1,1'-BIPHENYL-4,4'-DIYLDIOXY)DIANILINE;4,4'-(P-BIPHENYLENEDIOXY)DIANILINE;4,4'-BIS(4-AMINOPHENOXY)BIPHENYL;4,4-BIS(4-AMINOPHENOXY)BIPHENYL(44BAPOBP) 98%;4,4'-Bis(4-aminophenoxy)biphenyl ,99%;4,4'-(1,1'-Biphenyl-4,4'-diylbisoxy)bisaniline;4,4'-(Biphenyl-4,4'-diylbisoxy)bis(aniline);4,4'-[(1,1'-Biphenyl-4,4'-diyl)bis(oxy)]bisaniline
24 prices
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Brand
  • Alichem
  • Ambeed
  • American Custom Chemicals Corporation
  • Biosynth Carbosynth
  • Crysdot
  • CSNpharm
  • Frontier Specialty Chemicals
  • Sigma-Aldrich
  • TCI Chemical
  • TRC
Package
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  • 50mg
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  • ManufacturerAlichem
  • Product number13080858
  • Product description4,4'-Bis(4-Aminophenoxy)biphenyl
  • Packaging25g
  • Price$375.36
  • Updated2021-12-16
  • Buy
  • ManufacturerAlichem
  • Product number13080858
  • Product description4,4'-Bis(4-Aminophenoxy)biphenyl
  • Packaging500g
  • Price$965.66
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA432321
  • Product description4,4-Bis(4-aminophenoxy)biphenyl 98%
  • Packaging100mg
  • Price$5
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA432321
  • Product description4,4-Bis(4-aminophenoxy)biphenyl 98%
  • Packaging1g
  • Price$9
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA432321
  • Product description4,4-Bis(4-aminophenoxy)biphenyl 98%
  • Packaging5g
  • Price$25
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA432321
  • Product description4,4-Bis(4-aminophenoxy)biphenyl 98%
  • Packaging25g
  • Price$74
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA432321
  • Product description4,4-Bis(4-aminophenoxy)biphenyl 98%
  • Packaging100g
  • Price$245
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberCHM0024831
  • Product description4,4'-(1,1'-BIPHENYL-4,4'-DIYLDIOXY)DIANILINE 95.00%
  • Packaging10G
  • Price$1153.2
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberCHM0024831
  • Product description4,4'-(1,1'-BIPHENYL-4,4'-DIYLDIOXY)DIANILINE 95.00%
  • Packaging25G
  • Price$1204.99
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFB62604
  • Product description4,4'-Bis(4-aminophenoxy)biphenyl
  • Packaging10g
  • Price$53
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFB62604
  • Product description4,4'-Bis(4-aminophenoxy)biphenyl
  • Packaging25g
  • Price$106
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFB62604
  • Product description4,4'-Bis(4-aminophenoxy)biphenyl
  • Packaging50g
  • Price$180
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFB62604
  • Product description4,4'-Bis(4-aminophenoxy)biphenyl
  • Packaging100g
  • Price$306
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFB62604
  • Product description4,4'-Bis(4-aminophenoxy)biphenyl
  • Packaging250g
  • Price$612.5
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD45000579
  • Product description4,4'-Bis(4-Aminophenoxy)biphenyl 97%
  • Packaging500g
  • Price$902
  • Updated2021-12-16
  • Buy
  • ManufacturerCSNpharm
  • Product numberCSN23266
  • Product description4,4-Bis(4-aminophenoxy)biphenyl
  • Packaging10mg
  • Price$39
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Alichem 13080858 4,4'-Bis(4-Aminophenoxy)biphenyl 25g $375.36 2021-12-16 Buy
Alichem 13080858 4,4'-Bis(4-Aminophenoxy)biphenyl 500g $965.66 2021-12-16 Buy
Ambeed A432321 4,4-Bis(4-aminophenoxy)biphenyl 98% 100mg $5 2021-12-16 Buy
Ambeed A432321 4,4-Bis(4-aminophenoxy)biphenyl 98% 1g $9 2021-12-16 Buy
Ambeed A432321 4,4-Bis(4-aminophenoxy)biphenyl 98% 5g $25 2021-12-16 Buy
Ambeed A432321 4,4-Bis(4-aminophenoxy)biphenyl 98% 25g $74 2021-12-16 Buy
Ambeed A432321 4,4-Bis(4-aminophenoxy)biphenyl 98% 100g $245 2021-12-16 Buy
American Custom Chemicals Corporation CHM0024831 4,4'-(1,1'-BIPHENYL-4,4'-DIYLDIOXY)DIANILINE 95.00% 10G $1153.2 2021-12-16 Buy
American Custom Chemicals Corporation CHM0024831 4,4'-(1,1'-BIPHENYL-4,4'-DIYLDIOXY)DIANILINE 95.00% 25G $1204.99 2021-12-16 Buy
Biosynth Carbosynth FB62604 4,4'-Bis(4-aminophenoxy)biphenyl 10g $53 2021-12-16 Buy
Biosynth Carbosynth FB62604 4,4'-Bis(4-aminophenoxy)biphenyl 25g $106 2021-12-16 Buy
Biosynth Carbosynth FB62604 4,4'-Bis(4-aminophenoxy)biphenyl 50g $180 2021-12-16 Buy
Biosynth Carbosynth FB62604 4,4'-Bis(4-aminophenoxy)biphenyl 100g $306 2021-12-16 Buy
Biosynth Carbosynth FB62604 4,4'-Bis(4-aminophenoxy)biphenyl 250g $612.5 2021-12-16 Buy
Crysdot CD45000579 4,4'-Bis(4-Aminophenoxy)biphenyl 97% 500g $902 2021-12-16 Buy
CSNpharm CSN23266 4,4-Bis(4-aminophenoxy)biphenyl 10mg $39 2021-12-16 Buy

Properties

Melting point :197-200 °C(lit.)
Boiling point :571.4±50.0 °C(Predicted)
Density :1.226±0.06 g/cm3(Predicted)
storage temp. :Keep in dark place,Inert atmosphere,Room temperature
solubility :DMSO: 74 mg/mL (200.85 mM);;
form :powder to crystal
pka :5.10±0.10(Predicted)
color :White to Gray to Red
InChIKey :HYDATEKARGDBKU-UHFFFAOYSA-N
CAS DataBase Reference :13080-85-8(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

4,4'-Bis(4-aminophenoxy)biphenyl is known to be a potent Flk-1 (VEGFR2) inhibitor. It is also known to strongly inhibit Tie-2, Flt-1, Flt-3, Flt-4, Ret, Met (c-Met), and Axl. 4,4'-Bis(4-aminophenoxy)biphenyl has been shown to weakly inhibit Ron, PDGFR, and Flg (FGFR1). At a low concentration in MPNST cells, 4,4'-Bis(4-aminophenoxy)biphenyl has been observed to induce inhibition of inducible and constitutive Met phosphorylation and the resulting downstream signaling, as well as inhibiting HGF-induced MPNST cell invasion and migration. It has also been observed that this product induces marked inhibition of Flk-1 (VEGFR2) and Met phosphorylation in cytokine-stimulated human umbilical vein endothelial cells (HUVECs).

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