R788(Fostamatinib disodium)
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- $44 - $7030
- Product name: R788(Fostamatinib disodium)
- CAS: 1025687-58-4
- MF: C23H27FN6NaO9P
- MW: 604.46
- EINECS:-0
- MDL Number:MFCD15146370
- Synonyms:R788(Fostamatinib disodium);R788, Fostamatinib;R935788 (FostaMatinib disodiuM);FosD;FOSTAMATINIB;FOSD;TAMATINIB FOSDIUM;Tamatinib Fosdium;R788(prodrug of R406);R935788 (FostaMatinib disodiuM, R788)
26 prices
Selected condition：
Brand
- Adipogen Life Sciences
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Biorbyt Ltd
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- Labseeker
- Matrix Scientific
Package
- 1mg
- 5mg
- 10mg
- 50mg
- 100mg
- 250mg
- 1g
- 5g
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1122-M010
- Product descriptionR788disodiumsalt ≥95%
- Packaging10mg
- Price$324
- Updated2021-12-16
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1122-M050
- Product descriptionR788disodiumsalt ≥95%
- Packaging50mg
- Price$1048
- Updated2021-12-16
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1122-M100
- Product descriptionR788disodiumsalt ≥95%
- Packaging100mg
- Price$1836
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberSYN1122
- Product descriptionR788disodium
- Packaging50mg
- Price$990
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberSYN1122
- Product descriptionR788disodium
- Packaging100mg
- Price$1720
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000432
- Product descriptionFOSTAMATINIB DISODIUM 95.00%
- Packaging10MG
- Price$1127.86
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8332
- Product descriptionR788disodium
- Packaging10mg
- Price$168
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8332
- Product descriptionR788disodium
- Packaging100mg
- Price$713
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb154619
- Product descriptionR788 disodium (Fostamatinib) >98%
- Packaging100mg
- Price$542.3
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb154619
- Product descriptionR788 disodium (Fostamatinib) >98%
- Packaging250mg
- Price$986
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb154619
- Product descriptionR788 disodium (Fostamatinib) >98%
- Packaging1g
- Price$1949.9
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number18501
- Product descriptionR788 (sodium salt) ≥95%
- Packaging1mg
- Price$44
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number18501
- Product descriptionR788 (sodium salt) ≥95%
- Packaging5mg
- Price$193
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number18501
- Product descriptionR788 (sodium salt) ≥95%
- Packaging10mg
- Price$341
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-0427
- Product descriptionFostamatinibDisodium 99.88%
- Packaging5mg
- Price$96
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0427
- Product descriptionFostamatinibDisodium 99.88%
- Packaging10mg
- Price$144
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Adipogen Life Sciences | SYN-1122-M010 | R788disodiumsalt ≥95% | 10mg | $324 | 2021-12-16 | Buy |
| Adipogen Life Sciences | SYN-1122-M050 | R788disodiumsalt ≥95% | 50mg | $1048 | 2021-12-16 | Buy |
| Adipogen Life Sciences | SYN-1122-M100 | R788disodiumsalt ≥95% | 100mg | $1836 | 2021-12-16 | Buy |
| AK Scientific | SYN1122 | R788disodium | 50mg | $990 | 2021-12-16 | Buy |
| AK Scientific | SYN1122 | R788disodium | 100mg | $1720 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0000432 | FOSTAMATINIB DISODIUM 95.00% | 10MG | $1127.86 | 2021-12-16 | Buy |
| ApexBio Technology | A8332 | R788disodium | 10mg | $168 | 2021-12-16 | Buy |
| ApexBio Technology | A8332 | R788disodium | 100mg | $713 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb154619 | R788 disodium (Fostamatinib) >98% | 100mg | $542.3 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb154619 | R788 disodium (Fostamatinib) >98% | 250mg | $986 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb154619 | R788 disodium (Fostamatinib) >98% | 1g | $1949.9 | 2021-12-16 | Buy |
| Cayman Chemical | 18501 | R788 (sodium salt) ≥95% | 1mg | $44 | 2024-03-01 | Buy |
| Cayman Chemical | 18501 | R788 (sodium salt) ≥95% | 5mg | $193 | 2024-03-01 | Buy |
| Cayman Chemical | 18501 | R788 (sodium salt) ≥95% | 10mg | $341 | 2024-03-01 | Buy |
| ChemScene | CS-0427 | FostamatinibDisodium 99.88% | 5mg | $96 | 2021-12-16 | Buy |
| ChemScene | CS-0427 | FostamatinibDisodium 99.88% | 10mg | $144 | 2021-12-16 | Buy |
Properties
Melting point :>191°C (dec.)
storage temp. :Store at -20°C
solubility :DMSO (Slightly), Methanol (Slightly)
form :Solid
color :Off-White
Stability :Hygroscopic
storage temp. :Store at -20°C
solubility :DMSO (Slightly), Methanol (Slightly)
form :Solid
color :Off-White
Stability :Hygroscopic
Safety Information
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Description
Spleen tyrosine kinase (Syk) is a non-receptor tyrosine kinase that upon phosphorylation binds to immunoreceptor tyrosine-based activation motifs of FcRγ chains and mediates downstream signaling related to platelet function and inflammation. R788 is a prodrug of R406 , an inhibitor of Syk (Ki = 30 nM). R788 conversion to the biologically active R406 is catalyzed by the action of alkaline phosphatases present on the apical brush-border of the membranes of intestinal enterocytes. It produces anti-inflammatory and immunomodulating effects by inhibiting Syk-mediated IgG Fcγ receptor signaling, which prevents activation of mast cells, macrophages, and B cells, as well as related inflammatory responses. R788 has undergone clinical evaluation for efficacy in the treatment of rheumatoid arthritis.More related product prices
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