N,N-DIMETHYLFORMAMIDE-D7
Product identifier
- Product name: N,N-DIMETHYLFORMAMIDE-D7
- CBnumber: CB5671517
- CAS: 4472-41-7
- EINECS Number: 224-745-8
- Synonyms: N,N-Dimethylformamide-d7,N,N-bis(methyl-d3)formamide-d
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
- Uses advised against: none
Company Identification
- Company: Chemicalbook
- Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
- Telephone: 400-158-6606
GHS Label elements, including precautionary statements
-
Symbol(GHS)
- Signal wordDanger
Substance
- Product name: N,N-DIMETHYLFORMAMIDE-D7
- Synonyms: N,N-Dimethylformamide-d7,N,N-bis(methyl-d3)formamide-d
- CAS: 4472-41-7
- EC number: 224-745-8
- MF: C3H7NO
- MW: 73.1
Description of first aid measures
General adviceMost important symptoms and effects, both acute and delayed
Indication of any immediate medical attention and special treatment needed
Extinguishing media
Suitable extinguishing mediaSpecial hazards arising from the substance or mixture
Carbon oxides Nitrogen oxides (NOx) Combustible.
Fire may cause evolution of:
nitrogen oxides
Vapors are heavier than air and may spread along floors. Forms explosive mixtures with air at elevated temperatures.
Development of hazardous combustion gases or vapours possible in the event of fire.
Advice for firefighters
Stay in danger area only with self-contained breathing apparatus. Prevent skin contact by keeping a safe distance or by wearing suitable protective clothing.
Further information
Remove container from danger zone and cool with water. Suppress (knock down) gases/vapors/mists with a water spray jet. Prevent fire extinguishing water from contaminating surface water or the ground water system.
NFPA 704
| HEALTH | 2 | Intense or continued but not chronic exposure could cause temporary incapacitation or possible residual injury (e.g. diethyl ether, ammonium phosphate, iodine) | |
| FIRE | 2 | Must be moderately heated or exposed to relatively high ambient temperature before ignition can occur and multiple finely divided suspended solids that do not require heating before ignition can occur. Flash point between 37.8 and 93.3 °C (100 and 200 °F). (e.g. diesel fuel, sulfur) | |
| REACT | 1 | Normally stable, but can become unstable at elevated temperatures and pressures (e.g. propene) | |
| SPEC. HAZ. |
Personal precautions, protective equipment and emergency procedures
Advice for non-emergency personnel: Do not breathe vapors, aerosols. Avoid substance contact. Ensure adequate ventilation. Keep away from heat and sources of ignition.
Evacuate the danger area, observe emergency procedures, consult an expert. For personal protection see section 8.
Environmental precautions
Do not let product enter drains. Risk of explosion.
Methods and materials for containment and cleaning up
Cover drains. Collect, bind, and pump off spills. Observe possible material restrictions (see sections 7 and 10). Take up carefully with liquid-absorbent material (e.g.
Chemizorb?). Dispose of properly. Clean up affected area.
Reference to other sections
For disposal see section 13.
Precautions for safe handling
Advice on safe handling
Work under hood. Do not inhale substance/mixture. Avoid generation of vapours/aerosols.
Advice on protection against fire and explosion
Keep away from open flames, hot surfaces and sources of ignition.Take precautionary measures against static discharge.
Hygiene measures
Immediately change contaminated clothing. Apply preventive skin protection. Wash hands and face after working with substance.
For precautions see section 2.2.
Conditions for safe storage, including any incompatibilities
Storage conditions
Keep container tightly closed in a dry and well-ventilated place. Keep away from heat and sources of ignition. Keep locked up or in an area accessible only to qualified or authorized persons.
Recommended storage temperature see product label.
Specific end use(s)
Apart from the uses mentioned in section 1.2 no other specific uses are stipulated
control parameter
Hazard composition and occupational exposure limitsExposure controls
Personal protective equipmentUse equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Safety glasses
This recommendation applies only to the product stated in the safety data sheet, supplied by us and for the designated use. When dissolving in or mixing with other substances and under conditions deviating from those stated in EN374 please contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell, Internet: www.kcl.de).
Full contact
Material: butyl-rubber
Minimum layer thickness: 0,7 mm Break through time: 480 min Material tested:Butoject? (KCL 898)
This recommendation applies only to the product stated in the safety data sheet, supplied by us and for the designated use. When dissolving in or mixing with other substances and under conditions deviating from those stated in EN374 please contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell, Internet: www.kcl.de).
Splash contact Material: Viton?
Minimum layer thickness: 0,7 mm Break through time: 240 min
Material tested:Vitoject? (KCL 890 / Aldrich Z677698, Size M)
Flame retardant antistatic protective clothing.
Recommended Filter type: Filter A-(P3)
The entrepeneur has to ensure that maintenance, cleaning and testing of respiratory protective devices are carried out according to the instructions of the producer.
These measures have to be properly documented.
Do not let product enter drains. Risk of explosion.
Information on basic physicochemical properties
- Appearancecolorless liquid
- Odourweakly amine-like
- Odour Threshold0,329 ppm
- pHNo data available
- Melting point/freezing pointMelting point: -60 °C
- Initial boiling point and boiling range152 °C at 1.013 hPa
- Flash point58 °C - DIN 51755 Part 1
- Evaporation rateNo data available
- Flammability (solid, gas)No data available
- Upper/lower flammability or explosive limits Upper explosion limit: 16 %(V) Lower explosion limit: 2,2 %(V)
- Vapour pressure 3,77 hPa at 20 °C
- Vapour density 2,51
- Relative densityNo data available
- Water solubilityat 20 °C soluble
- Partition coefficient: n-octanol/waterlog Pow: -0,85 - Bioaccumulation is not expected.
- Autoignition temperatureNo data available
- Decomposition temperatureNo data available
- ViscosityViscosity, kinematic: No data available Viscosity, dynamic: No data available
- Explosive propertiesNo data available
- Oxidizing propertiesNo data available
Other safety information
Relative vapor density
2,51
Reactivity
Vapor/air-mixtures are explosive at intense warming.
Chemical stability
The product is chemically stable under standard ambient conditions (room temperature) .
Possibility of hazardous reactions
Violent reactions possible with:
Alkali metals halogens halides Reducing agents
triethylaluminium nitrates
metallic oxides nonmetallic oxides Halogenated hydrocarbon Isocyanates
sodium
Sodium borohydride hydrides
Oxidizing agents Oxides of phosphorus
A risk of explosion and/or of toxic gas formation exists with the following substances: azides
Bromine Chlorine
chromium(VI) oxide potassium permanganate triethylaluminium chlorates
Halogenated hydrocarbon with
Iron
Conditions to avoid
Heating.
Incompatible materials
various plastics, Copper, Copper alloys, Tin
Hazardous decomposition products
In the event of fire: see section 5
Information on toxicological effects
Acute toxicityRemarks: The value is given in analogy to the following substances: N,N- dimethylformamide
LC50 Inhalation - Rat - 4 h - 9 - 15 mg/l Remarks: (Lit.)
The value is given in analogy to the following substances: N,N-dimethylformamide LD50 Dermal - Rabbit - 1.500 mg/kg
Remarks: (IUCLID)
The value is given in analogy to the following substances: N,N-dimethylformamide
Result: No skin irritation Remarks: (IUCLID)
The value is given in analogy to the following substances: N,N-dimethylformamide
The value is given in analogy to the following substances: N,N-dimethylformamide
The value is given in analogy to the following substances: N,N-dimethylformamide Sensitisation test: - Mouse
Result: negative
(OECD Test Guideline 406)
Remarks: The value is given in analogy to the following substances: N,N- dimethylformamide
Test system: Salmonella typhimurium
Metabolic activation: with and without metabolic activation Result: negative
Remarks: (ECHA)
The value is given in analogy to the following substances: N,N-dimethylformamide Test Type: Micronucleus test
Species: Mouse
Cell type: Bone marrow
Application Route: Intraperitoneal injection
Result: negative Remarks: (ECHA)
The value is given in analogy to the following substances: N,N-dimethylformamide
Toxicity
7.100 mg/l - 96 h (US-EPA)
Remarks: The value is given in analogy to the following substances: N,N-dimethylformamide
static test EC50 - Daphnia magna (Water flea) - 13.100 mg/l - 48 h (OECD Test Guideline 202)
Remarks: The value is given in analogy to the following substances: N,N-dimethylformamide
(DIN 38412)
Remarks: The value is given in analogy to the following substances: N,N-dimethylformamide
The value is given in analogy to the following substances: N,N- dimethylformamide
Persistence and degradability
Biodegradability Result: - Readily biodegradable.
aerobic - Exposure time 21 d (OECD Test Guideline 301E)
Remarks: The value is given in analogy to the following substances: N,N-dimethylformamide
Bioaccumulative potential
No data available
Mobility in soil
No data available
Results of PBT and vPvB assessment
This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
Other adverse effects
No data available
Waste treatment methods
Product
See www.retrologistik.com for processes regarding the return of chemicals and containers, or contact us there if you have further questions.
UN number
ADR/RID: 2265 IMDG: 2265 IATA: 2265
UN proper shipping name
| | ADR/RID: N,N-DIMETHYLFORMAMIDE IMDG: N,N-DIMETHYLFORMAMIDE | |
| IATA: N,N-Dimethylformamide | ||
| 14.3 | Transport hazard class(es) ADR/RID: 3 IMDG: 3 | IATA: 3 |
| 14.4 | Packaging group ADR/RID: III IMDG: III | IATA: III |
| 14.5 | Environmental hazards ADR/RID: no IMDG Marine pollutant: no | IATA: no |
| 14.6 | Special precautions for user No data available | |
Safety, health and environmental regulations/legislation specific for the substance or mixture
Regulations on the Safety Management of Hazardous ChemicalsAbbreviations and acronyms
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- CAS: Chemical Abstracts Service
- EC50: Effective Concentration 50%
- IATA: International Air Transportation Association
- IMDG: International Maritime Dangerous Goods
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- STEL: Short term exposure limit
- TWA: Time Weighted Average
References
【1】CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
【2】ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
【3】ECHA - European Chemicals Agency, website: https://echa.europa.eu/
【4】eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
【5】ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
【6】Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
【7】HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
【8】IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
【9】IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
【10】Sigma-Aldrich, website: https://www.sigmaaldrich.com/
The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.