Chloroform-d
Product identifier
- Product name: Chloroform-d
- CBnumber: CB2103569
- CAS: 865-49-6
- EINECS Number: 212-742-4
- Synonyms: chloroform-d,deuterated chloroform
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
- Uses advised against: none
Company Identification
- Company: Chemicalbook
- Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
- Telephone: 400-158-6606
GHS Label elements, including precautionary statements
-
Symbol(GHS)
- Signal wordDanger
Substance
- Product name: Chloroform-d
- Synonyms: chloroform-d,deuterated chloroform
- CAS: 865-49-6
- EC number: 212-742-4
- MF: CCl3D
- MW: 120.38
Description of first aid measures
General adviceMost important symptoms and effects, both acute and delayed
Indication of any immediate medical attention and special treatment needed
Notes to physician
Extinguishing media
Suitable extinguishing mediaSpecial hazards arising from the substance or mixture
Carbon oxides Hydrogen chloride gas Not combustible.
Fire may cause evolution of:
Hydrogen chloride gas, Phosgene
Ambient fire may liberate hazardous vapours.
Advice for firefighters
Stay in danger area only with self-contained breathing apparatus. Prevent skin contact by keeping a safe distance or by wearing suitable protective clothing.
Suppress (knock down) gases/vapors/mists with a water spray jet. Prevent fire extinguishing water from contaminating surface water or the ground water system.
NFPA 704
| HEALTH | 3 | Short exposure could cause serious temporary or moderate residual injury (e.g. liquid hydrogen, sulfuric acid, calcium hypochlorite, hexafluorosilicic acid) | |
| FIRE | 1 | Materials that require considerable preheating, under all ambient temperature conditions, before ignition and combustion can occur. Includes some finely divided suspended solids that do not require heating before ignition can occur. Flash point at or above 93.3 °C (200 °F). (e.g. mineral oil, ammonia) | |
| REACT | 1 | Normally stable, but can become unstable at elevated temperatures and pressures (e.g. propene) | |
| SPEC. HAZ. |
Personal precautions, protective equipment and emergency procedures
Advice for non-emergency personnel: Do not breathe vapors, aerosols. Avoid substance contact. Ensure adequate ventilation. Evacuate the danger area, observe emergency procedures, consult an expert.
For personal protection see section 8.
Environmental precautions
Do not let product enter drains.
Methods and materials for containment and cleaning up
Cover drains. Collect, bind, and pump off spills. Observe possible material restrictions (see sections 7 and 10). Take up carefully with liquid-absorbent material (e.g.
Chemizorb?). Dispose of properly. Clean up affected area.
Reference to other sections
For disposal see section 13.
Precautions for safe handling
Advice on safe handling
Work under hood. Do not inhale substance/mixture. Avoid generation of vapours/aerosols.
Hygiene measures
Immediately change contaminated clothing. Apply preventive skin protection. Wash hands and face after working with substance.
For precautions see section 2.2.
Conditions for safe storage, including any incompatibilities
Storage conditions
Tightly closed. Keep in a well-ventilated place. Keep locked up or in an area accessible only to qualified or authorized persons.
Recommended storage temperature see product label.
control parameter
Hazard composition and occupational exposure limitsExposure controls
Appropriate engineering controlsImmediately change contaminated clothing. Apply preventive skin protection. Wash hands and face after working with substance.
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Safety glasses
This recommendation applies only to the product stated in the safety data sheet, supplied by us and for the designated use. When dissolving in or mixing with other substances and under conditions deviating from those stated in EN374 please contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell, Internet: www.kcl.de).
Full contact Material: Viton?
Minimum layer thickness: 0.7 mm Break through time: 480 min
Material tested:Vitoject? (KCL 890 / Aldrich Z677698, Size M)
This recommendation applies only to the product stated in the safety data sheet, supplied by us and for the designated use. When dissolving in or mixing with other substances and under conditions deviating from those stated in EN374 please contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell, Internet: www.kcl.de).
Splash contact Material: butyl-rubber
Minimum layer thickness: 0.7 mm Break through time: 10 min
Material tested:Butoject? (KCL 898)
protective clothing
required when vapours/aerosols are generated.
Our recommendations on filtering respiratory protection are based on the following standards: DIN EN 143, DIN 14387 and other accompanying standards relating to the used respiratory protection system.
Do not let product enter drains.
Information on basic physicochemical properties
- Appearancecolorless liquid
- Odourcharacteristic
- Odour ThresholdNo data available
- pHNo data available
- Melting point/freezing pointMelting point/range: -64.69 - 64.15 °C at 4 hPa
- Initial boiling point and boiling range ca.61.5 °C at ca.1,013.25 hPa
- Flash point>60 °C at ca.1,019.2 hPa - closed cup - Regulation (EC) No. 440/2008, Annex, A.9
- Evaporation rateNo data available
- Flammability (solid, gas)No data available
- Upper/lower flammability or explosive limitsNo data available
- Vapour pressure ca.265.31 hPa at ca.25 °C
- Vapour density 4.12 - (Air = 1.0)
- Relative densityca.1.445 at 20 °C - OECD Test Guideline 109
- Water solubility4.6 g/l at 20 °C - Regulation (EC) No. 440/2008, Annex, A.6
- Partition coefficient: n-octanol/waterlog Pow: 1.5 at 20 °C - Bioaccumulation is not expected.
- Autoignition temperatureNo data available
- Decomposition temperature Distillable in an undecomposed state at normal pressure.
- ViscosityViscosity, kinematic: No data available Viscosity, dynamic: No data available
- Explosive propertiesNo data available
- Oxidizing propertiesNo data available
Other safety information
Surface tension 72.3 mN/m at 0.99g/l at 20 °C
- Surface tension
Relative vapor density
4.12 - (Air = 1.0)
Chemical stability
The product is chemically stable under standard ambient conditions (room temperature) .
Possibility of hazardous reactions
Risk of explosion with: Ammonia
Amines nitrogen oxides bases
Oxygen alkali amides
organic nitro compounds Alcohols
alkali hydroxides strong alkalis Fluorine
peroxi compounds Alkaline earth metals Alkali metals
Powdered metals Methanol
with alcoholates Methanol with
strong alkalis Iron
in powder form various alloys sensitive to shock Methanol
with
Sodium hydroxide magnesium
in powder form Oxygen
with
alkali compounds Aluminum
in powder form Acetone
with
alkali compounds Potassium sensitive to shock sodium
sensitive to shock
Violent reactions possible with: phosphines bis(dimethylamino)dimethyl tin nonmetallic hydrogen compounds Powdered metals
Light metals Ketones mineral acids
Strong oxidizing agents semimetallic hydrogen compounds
Conditions to avoid
no information available
Incompatible materials
rubber, various plastics
Hazardous decomposition products
In the event of fire: see section 5
Information on toxicological effects
Acute toxicityAcute toxicity estimate Inhalation - 3.1 mg/l (Expert judgment)
Dermal
Result: Irritating to skin. - 24 h Remarks: (ECHA)
Drying-out effect resulting in rough and chapped skin.
Result: Irritating to eyes. Remarks: (ECHA)
Test system: Salmonella typhimurium
Metabolic activation: with and without metabolic activation Result: negative
Remarks: (ECHA)
Test Type: In vitro mammalian cell gene mutation test Test system: mouse lymphoma cells
Metabolic activation: with and without metabolic activation Result: positive
Remarks: (ECHA)
Test Type: Chromosome aberration test Species: Rat
Cell type: Bone marrow Application Route: Oral
Result: positive Remarks: (ECHA)
The value is given in analogy to the following substances: Chloroform
Remarks: Classified according to Regulation (EU) 1272/2008, Annex VI (Table 3.1/3.2)
Toxicity
static test EC50 - Daphnia magna (Water flea) - 79 mg/l - 48 h Remarks: (ECHA)
Remarks: (ECHA)
Remarks: (ECHA)
Persistence and degradability
Biodegradability aerobic - Exposure time 14 d
Result: 0 % - Not readily biodegradable. (OECD Test Guideline 301C)
Theoretical oxygen demand
1,346 mg/g
Bioaccumulative potential
No data available
Mobility in soil
No data available
Results of PBT and vPvB assessment
PBT/vPvB assessment not available as chemical safety assessment not required/not conducted
Other adverse effects
No data available
Waste treatment methods
Product
Offer surplus and non-recyclable solutions to a licensed disposal company.
UN number
ADR/RID: 1888 IMDG: 1888 IATA-DGR: 1888
UN proper shipping name
Transport hazard class(es)
ADR/RID: 6.1 IMDG: 6.1 IATA-DGR: 6.1
Packaging group
ADR/RID: III IMDG: III IATA-DGR: III
Environmental hazards
ADR/RID: no IMDG Marine pollutant: no IATA-DGR: no
Special precautions for user
Based on chemical properties, choose appropriate tools and conditions of transport. Transporting tools shall be equipped with appropriate and sufficient firefighting equipment and emergency leaking installations. If transporting by road, please go along the specified route.
Incompatible materials
rubber, various plastics
Safety, health and environmental regulations/legislation specific for the substance or mixture
Regulations on the Safety Management of Hazardous ChemicalsAbbreviations and acronyms
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- CAS: Chemical Abstracts Service
- EC50: Effective Concentration 50%
- IATA: International Air Transportation Association
- IMDG: International Maritime Dangerous Goods
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- STEL: Short term exposure limit
- TWA: Time Weighted Average
References
【1】CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
【2】ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
【3】ECHA - European Chemicals Agency, website: https://echa.europa.eu/
【4】eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
【5】ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
【6】Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
【7】HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
【8】IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
【9】IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
【10】Sigma-Aldrich, website: https://www.sigmaaldrich.com/
The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.