BUTRALIN
Product identifier
- Product name: BUTRALIN
- CBnumber: CB2496418
- CAS: 33629-47-9
- EINECS Number: 251-607-4
- Synonyms: Butralin,Butraline
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
- Uses advised against: none
Company Identification
- Company: Chemicalbook
- Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
- Telephone: 400-158-6606
Classification of the substance or mixture
Acute toxicity - Category 4, Oral
Reproductive toxicity, Category 2
Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1
Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 1
Label elements
Pictogram(s)
- Signal wordWarning
H302 Harmful if swallowed
H319 Causes serious eye irritation
H341 Suspected of causing genetic defects
H410 Very toxic to aquatic life with long lasting effects
P273 Avoid release to the environment.
P281 Use personal protective equipment as required.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P501 Dispose of contents/container to..…
P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P203 Obtain, read and follow all safety instructions before use.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P273 Avoid release to the environment.
P301+P317 IF SWALLOWED: Get medical help.
P330 Rinse mouth.
P318 IF exposed or concerned, get medical advice.
P391 Collect spillage.
P405 Store locked up.
P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards
no data available
Substance
- Product name: BUTRALIN
- Synonyms: Butralin,Butraline
- CAS: 33629-47-9
- EC number: 251-607-4
- MF: C14H21N3O4
- MW: 295.33
Description of first aid measures
If inhaledMove the victim into fresh air. If breathing is difficult, give oxygen. If not breathing, give artificial respiration and consult a doctor immediately. Do not use mouth to mouth resuscitation if the victim ingested or inhaled the chemical.
Take off contaminated clothing immediately. Wash off with soap and plenty of water. Consult a doctor.
Rinse with pure water for at least 15 minutes. Consult a doctor.
Rinse mouth with water. Do not induce vomiting. Never give anything by mouth to an unconscious person. Call a doctor or Poison Control Center immediately.
Most important symptoms and effects, both acute and delayed
no data available
Indication of any immediate medical attention and special treatment needed
Skin decontamination. Skin contamination should be treated promptly by washing with soap and water. Contamination of the eyes should be treated immediately by prolonged flushing of the eyes with large amounts of clean water. If dermal or ocular irritation persists, medical attention should be obtained without delay. Other herbicides
Extinguishing media
Use dry chemical, carbon dioxide or alcohol-resistant foam.
Specific Hazards Arising from the Chemical
no data available
Advice for firefighters
Wear self-contained breathing apparatus for firefighting if necessary.
Personal precautions, protective equipment and emergency procedures
Avoid dust formation. Avoid breathing mist, gas or vapours.Avoid contacting with skin and eye. Use personal protective equipment.Wear chemical impermeable gloves. Ensure adequate ventilation.Remove all sources of ignition. Evacuate personnel to safe areas.Keep people away from and upwind of spill/leak.
Environmental precautions
Prevent further spillage or leakage if it is safe to do so. Do not let the chemical enter drains. Discharge into the environment must be avoided.
Methods and materials for containment and cleaning up
If a spill occurs, clean it up promptly. Don't wash it away. Instead, sprinkle the spill with sawdust, vermiculite, or kitty litter. Sweep it into a plastic garbage bag, and dispose of it as directed on the pesticide product label.
Precautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Safe Storage of Pesticides. Always store pesticides in their original containers, complete with labels that list ingredients, directions for use, and first aid steps in case of accidental poisoning. Never store pesticides in cabinets with or near food, animal feed, or medical supplies. Do not store pesticides in places where flooding is possible or in places where they might spill or leak into wells, drains, ground water, or surface water.
Control parameters
Occupational Exposure limit valuesno data available
no data available
Exposure controls
Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.
Individual protection measures
Eye/face protectionWear tightly fitting safety goggles with side-shields conforming to EN 166(EU) or NIOSH (US).
Wear fire/flame resistant and impervious clothing. Handle with gloves. Gloves must be inspected prior to use. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it.
If the exposure limits are exceeded, irritation or other symptoms are experienced, use a full-face respirator.
no data available
Information on basic physicochemical properties
- Physical stateneat
- Colour
Yellow orange crystals
- Odour
Slightly aromatic odor
- Melting point/freezing point
61°C
- Boiling point or initial boiling point and boiling range
381.3°C at 760 mmHg
- Flammability
no data available
- Lower and upper explosion limit/flammability limit
no data available
- Flash point
184.4°C
- Auto-ignition temperature
no data available
- Decomposition temperature
no data available
- pH
no data available
- Kinematic viscosity
no data available
- Solubility
Solubility in ethanol 73, methanol 98 and hexane 300 g/L at 25-26 deg C. Solubility in dichloroethane 146, benzene 270 and acetone 448 g/100 mL at 24 deg C.
- Partition coefficient n-octanol/water
log Kow = 4.93 at 23 deg C
- Vapour pressure
1.3X10-5 mm Hg at 25 deg C
- Density and/or relative density
1.185 g/cm3
- Relative vapour density
no data available
- Particle characteristics
no data available
Reactivity
no data available
Chemical stability
Hydrolytically and photochemically stable. Concentrates are stable on storage under dry conditions >3 years, but should not be stored <-5 deg C or allowed to freeze.
Possibility of hazardous reactions
no data available
Conditions to avoid
no data available
Incompatible materials
Incompatible with strong oxidizing agents.
Hazardous decomposition products
Decomposes at 265 deg C.
Acute toxicity
- Oral: LD50 Rat oral 2500 mg/kg
- Inhalation: LC50 Rat inhalation 50 g/cu m/ 4 hr
- Dermal: LD50 Rabbit percutaneous > or =2000 mg/kg Technical product
Skin corrosion/irritation
no data available
Serious eye damage/irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
no data available
Reproductive toxicity
no data available
STOT-single exposure
no data available
STOT-repeated exposure
no data available
Aspiration hazard
no data available
Toxicity
- Toxicity to fish: LC50 Lepomis macrochirus (Bluegill sunfish) 1.0 ppm/96 hr (95% confidence interval: 0.7-1.4 ppm); static /formulated product
- Toxicity to daphnia and other aquatic invertebrates: EC50 Daphnia magna (Water flea) 1.0 ppm/48 hr; static /formulated product
- Toxicity to algae: no data available
- Toxicity to microorganisms: no data available
Persistence and degradability
AEROBIC: Butralin is degraded by soil microflora such as Paecilomyces sp; the major biodegradation product is 4-tert butyl 2,6 dinitroanaline(1). 14C-labeled butralin, applied at a concentration of 10 ppm to Chillum silt loam soil incubated at 70% field moisture capacity, was 57% degraded after 6 months; 98% applied 14C was recovered after 2 months(2). Under greenhouse conditions, butralin exhibited half-lives ranging from 21-52 days, with a mean half-life of 40 days(3). Using a Sharkey clay (4% sand, 25% silt, 71% clay, 4.2% organic matter) and Bosket clay loam (20% sand, 60% silt, 20% clay, 1.5% organic matter) soils in greenhouse experiments, butralin, applied at 8 umole/kg to 2,000 g soil, exhibited half-lives of 52 and 29 days, respectively(3).
Bioaccumulative potential
An estimated BCF of 1248 was calculated for butralin(SRC), using a log Kow of 4.93(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is very high(SRC), provided the compound is not metabolized by the organism(SRC).
Mobility in soil
The Koc of butralin has been reported as 3,400(1). According to a classification scheme(2), this Koc value suggests that butralin is expected to have slight mobility in soil. Butralin was strongly adsorbed by organic matter, as shown by 77, 82, and 78% adsorption of addition of 2.5, 5.0, and 10X10-6 M concentrations, respectively(3). The same concentrations added to montmorillonite resulted in 21, 13, and 9% adsorption, respectively(3). Subsequent desorption studies showed very little desorption from organic matter by either water or 1 N CaCl solution, results being 13.2 and 11.1%, respectively; 91.7 and 68.4% desorption, respectively, was desorbed from montmorillonite(3). Metapeake loam, treated 7 months earlier with 10 ppm butralin, contained 27% nonextractable radioactivity(1).
Other adverse effects
no data available
Disposal methods
ProductThe material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
UN Number
ADR/RID: Not dangerous goods. (For reference only, please check.)
IMDG: Not dangerous goods. (For reference only, please check.)
IATA: Not dangerous goods. (For reference only, please check.)
UN Proper Shipping Name
ADR/RID: Not dangerous goods. (For reference only, please check.)
IMDG: Not dangerous goods. (For reference only, please check.)
IATA: Not dangerous goods. (For reference only, please check.)
Transport hazard class(es)
ADR/RID: Not dangerous goods. (For reference only, please check.)
IMDG: Not dangerous goods. (For reference only, please check.)
IATA: Not dangerous goods. (For reference only, please check.)
Packing group, if applicable
ADR/RID: Not dangerous goods. (For reference only, please check.)
IMDG: Not dangerous goods. (For reference only, please check.)
IATA: Not dangerous goods. (For reference only, please check.)
Environmental hazards
ADR/RID: Yes
IMDG: Yes
IATA: Yes
Special precautions for user
no data available
Transport in bulk according to IMO instruments
no data available
Safety, health and environmental regulations specific for the product in question
European Inventory of Existing Commercial Chemical Substances (EINECS)Abbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
- IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
- HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
- IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
- eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
- CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
- ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
- ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
- Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
- ECHA - European Chemicals Agency, website: https://echa.europa.eu/
The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.