Acetic acid
Product identifier
- Product name: Acetic acid
- CBnumber: CB7854064
- CAS: 64-19-7
- EINECS Number: 200-580-7
- Synonyms: Acetic acid,AcOH
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
- Uses advised against: none
Company Identification
- Company: Chemicalbook
- Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
- Telephone: 400-158-6606
GHS Label elements, including precautionary statements
-
Symbol(GHS)
- Signal wordDanger
Substance
- Product name: Acetic acid
- Synonyms: Acetic acid,AcOH
- CAS: 64-19-7
- EC number: 200-580-7
- MF: C2H4O2
- MW: 60.05
Description of first aid measures
General adviceMost important symptoms and effects, both acute and delayed
Indication of any immediate medical attention and special treatment needed
Extinguishing media
Suitable extinguishing mediaSpecial hazards arising from the substance or mixture
Carbon oxides Combustible.
Advice for firefighters
Wear self-contained breathing apparatus for firefighting if necessary.
Further information
Use water spray to cool unopened containers.
NFPA 704
| HEALTH | 3 | Short exposure could cause serious temporary or moderate residual injury (e.g. liquid hydrogen, sulfuric acid, calcium hypochlorite, hexafluorosilicic acid) | |
| FIRE | 2 | Must be moderately heated or exposed to relatively high ambient temperature before ignition can occur and multiple finely divided suspended solids that do not require heating before ignition can occur. Flash point between 37.8 and 93.3 °C (100 and 200 °F). (e.g. diesel fuel, sulfur) | |
| REACT | 0 | Normally stable, even under fire exposure conditions, and is not reactive with water (e.g. helium,N2) | |
| SPEC. HAZ. |
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Remove all sources of ignition. Evacuate personnel to safe areas.
Beware of vapours accumulating to form explosive concentrations. Vapours can accumulate in low areas.
For personal protection see section 8.
Environmental precautions
Prevent further leakage or spillage if safe to do so. Do not let product enter drains.
Methods and materials for containment and cleaning up
Contain spillage, and then collect with non-combustible absorbent material, (e.g. sand, earth, diatomaceous earth, vermiculite) and place in container for disposal according to local / national regulations (see section 13).
Reference to other sections
For disposal see section 13.
Precautions for safe handling
Avoid inhalation of vapour or mist.
Keep away from sources of ignition - No smoking.Take measures to prevent the build up of electrostatic charge.
For precautions see section 2.2.
Conditions for safe storage, including any incompatibilities
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Moisture sensitive.
Specific end use(s)
Apart from the uses mentioned in section 1.2 no other specific uses are stipulated
control parameter
Hazard composition and occupational exposure limitsExposure controls
Appropriate engineering controlsHandle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.
Tightly fitting safety goggles. Faceshield (8-inch minimum). Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands.
The selected protective gloves have to satisfy the specifications of Regulation (EU) 2016/425 and the standard EN 374 derived from it.
Full contact
Material: butyl-rubber
Minimum layer thickness: 0,3 mm Break through time: 480 min
Material tested:Butoject? (KCL 897 / Aldrich Z677647, Size M)
Splash contact
Material: Nature latex/chloroprene Minimum layer thickness: 0,6 mm Break through time: 32 min
Material tested:Lapren? (KCL 706 / Aldrich Z677558, Size M)
data source: KCL GmbH, D-36124 Eichenzell, phone +49 (0)6659 87300, e-mail sales@kcl.de, test method: EN374
If used in solution, or mixed with other substances, and under conditions which differ from EN 374, contact the supplier of the CE approved gloves. This recommendation is advisory only and must be evaluated by an industrial hygienist and safety officer familiar with the specific situation of anticipated use by our customers. It should not be construed as offering an approval for any specific use scenario.
Complete suit protecting against chemicals, Flame retardant antistatic protective clothing., The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Where risk assessment shows air-purifying respirators are appropriate use a full- face respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls. If the respirator is the sole means of protection, use a full-face supplied air respirator. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Prevent further leakage or spillage if safe to do so. Do not let product enter drains.
Information on basic physicochemical properties
- Appearancecolourless liquid
- Odourstinging
- Odour Threshold0.006ppm
- pH2,5 at 50 g/l at 20 °C
- Melting point/freezing pointMelting point/range: 16,2 °C - lit.
- Initial boiling point and boiling range117 - 118 °C - lit.
- Flash point39 °C - closed cup
- Evaporation rateNo data available
- Flammability (solid, gas)Not applicable
- Upper/lower flammability or explosive limitsUpper explosion limit: 19,9 %(V)Lower explosion limit: 4 %(V)
- Vapour pressure20,79 hPa at 25 °C
- Vapour density2,07
- Relative density1,049 g/cm3 at 25 °C
- Water solubility602,9 g/l at 25 °C at 1.013 hPa - completely soluble
- Partition coefficient: n-octanol/waterlog Pow: -0,17 at 25 °C - Bioaccumulation is not expected., (ECHA)
- Autoignition temperature 463 °C
- Decomposition temperature Distillable in an undecomposed state at normal pressure.
- Viscosity1,17 mm2/s at 20 °C -
- Explosive propertiesNo data available
- Oxidizing propertiesNo data available
- Henry's Law Constant133, 122, 6.88, and 1.27 at pH values of 2.13, 3.52, 5.68, and 7.14, respectively (25 °C, Hakuta et al., 1977)
- λmaxλ: 260 nm Amax: 0.05
λ: 270 nm Amax: 0.02
λ: 300 nm Amax: 0.01
λ: 500 nm Amax: 0.01
Other safety information
Surface tension 28,8 mN/m at 10,0 °C
Relative vapour density
2,07
Reactivity
No data available
Chemical stability
Stable under recommended storage conditions.
Possibility of hazardous reactions
No data available
Conditions to avoid
Heat, flames and sparks.
Incompatible materials
Oxidizing agents, Soluble carbonates and phosphates, Hydroxides, Metals, Peroxides, permanganates, for example potassium permanganate, Amines, Alcohols, Nitric acid
Hazardous decomposition products
Hazardous decomposition products formed under fire conditions. - Carbon oxides Other decomposition products - No data available
In the event of fire: see section 5
Information on toxicological effects
Acute toxicityRemarks: (RTECS)
LC50 Inhalation - Mouse - 4 h - 2.819 mg/l Remarks: (RTECS)
Result: Causes burns. - 4 h (OECD Test Guideline 404) Remarks: (IUCLID)
Result: Causes burns. - 4 h (OECD Test Guideline 405) Remarks: (IUCLID)
Causes serious eye damage.
Salmonella typhimurium Result: negative
Mutagenicity (mammal cell test): chromosome aberration. Chinese hamster ovary cells
Result: negative
Mutagenicity (micronucleus test)
Rat - male and female - Bone marrow Result: negative
Material is extremely destructive to tissue of the mucous membranes and upper respiratory tract, eyes, and skin., spasm, inflammation and edema of the larynx, spasm, inflammation
and edema of the bronchi, pneumonitis, pulmonary edema, burning sensation, Cough, wheezing, laryngitis, Shortness of breath, Headache, Nausea, Vomiting, Ingestion or inhalation of concentrated acetic acid causes damage to tissues of the respiratory and digestive tracts. Symptoms include: hematemesis, bloody diarrhea, edema and/or perforation of the esophagus and pylorus, pancreatitis, hematuria, anuria, uremia, albuminuria, hemolysis, convulsions, bronchitis, pulmonary edema, pneumonia, cardiovascular collapse, shock, and death. Direct contact or exposure to high concentrations of vapor with skin or eyes can cause: erythema, blisters, tissue destruction with slow healing, skin blackening, hyperkeratosis, fissures, corneal erosion, opacification, iritis, conjunctivitis, and possible blindness.
To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.
Toxicity
1.000 mg/l - 96 h
(OECD Test Guideline 203)
static test EC50 - Daphnia magna (Water flea) - > 1.000 mg/l - 48 h (OECD Test Guideline 202)
Remarks: neutral(maximum permissible toxic concentration)(Lit.)
microtox test EC50 - Photobacterium phosphoreum - 11 mg/l - 15 min
Remarks: (IUCLID)
Persistence and degradability
Biodegradability Result: 99 % - Readily biodegradable.
(OECD Test Guideline 301D) Remarks: (HSDB)
Result: 95 % - Readily eliminated from water (OECD Test Guideline 302B)
Biochemical Oxygen Demand (BOD)
880 mg/g Remarks: (Lit.)
Ratio BOD/ThBOD 76 %
Remarks: (IUCLID)
Bioaccumulative potential
No data available
Mobility in soil
No data available
Results of PBT and vPvB assessment
This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
Other adverse effects
Additional ecological information
No data available
Waste treatment methods
Product
Offer surplus and non-recyclable solutions to a licensed disposal company. Waste material must be disposed of in accordance with the Directive on waste 2008/98/EC as well as other national and local regulations. Leave chemicals in original containers. No mixing with other waste. Handle uncleaned containers like the product itself.
IncompatibilitiesAcetic acid reacts with alkaline substances.
Waste DisposalDissolve or mix the material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber. All federal, state, and local environmental regulations must be observed
Contaminated packaging
Dispose of as unused product.
UN number
ADR/RID: 2789 IMDG: 2789 IATA: 2789
UN proper shipping name
| | ADR/RID: ACETIC ACID, GLACIAL IMDG: ACETIC ACID, GLACIAL | |
| IATA: Acetic acid, glacial | ||
| 14.3 | Transport hazard class(es) ADR/RID: 8 (3) IMDG: 8 (3) | IATA: 8 (3) |
| 14.4 | Packaging group ADR/RID: II IMDG: II | IATA: II |
| 14.5 | Environmental hazards ADR/RID: no IMDG Marine pollutant: no | IATA: no |
| 14.6 | Special precautions for user No data available | |
Safety, health and environmental regulations/legislation specific for the substance or mixture
Regulations on the Safety Management of Hazardous ChemicalsAbbreviations and acronyms
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- CAS: Chemical Abstracts Service
- EC50: Effective Concentration 50%
- IATA: International Air Transportation Association
- IMDG: International Maritime Dangerous Goods
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- STEL: Short term exposure limit
- TWA: Time Weighted Average
References
【1】CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
【2】ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
【3】ECHA - European Chemicals Agency, website: https://echa.europa.eu/
【4】eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
【5】ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
【6】Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
【7】HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
【8】IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
【9】IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
【10】Sigma-Aldrich, website: https://www.sigmaaldrich.com/
Other Information
The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.