3-Aminopropyltriethoxysilane
Product identifier
- Product name: 3-Aminopropyltriethoxysilane
- CBnumber: CB8686147
- CAS: 919-30-2
- EINECS Number: 213-048-4
- Synonyms: APTES,3-Aminopropyltriethoxysilane
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
- Uses advised against: none
Company Identification
- Company: Chemicalbook
- Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
- Telephone: 400-158-6606
GHS Label elements, including precautionary statements
-
Symbol(GHS)
- Signal wordDanger
Substance
- Product name: 3-Aminopropyltriethoxysilane
- Synonyms: APTES,3-Aminopropyltriethoxysilane
- CAS: 919-30-2
- EC number: 213-048-4
- MF: C9H23NO3Si
- MW: 221.37
Description of first aid measures
General adviceMost important symptoms and effects, both acute and delayed
Indication of any immediate medical attention and special treatment needed
Extinguishing media
Suitable extinguishing mediaSpecial hazards arising from the substance or mixture
Carbon oxides Nitrogen oxides (NOx) silicon oxides Combustible.
Vapors are heavier than air and may spread along floors. Forms explosive mixtures with air on intense heating.
Development of hazardous combustion gases or vapours possible in the event of fire.
Advice for firefighters
Stay in danger area only with self-contained breathing apparatus. Prevent skin contact by keeping a safe distance or by wearing suitable protective clothing.
Further information
Under fire conditions, material may decompose to form flammable and/or explosive mixtures in air.Remove container from danger zone and cool with water. Suppress (knock down) gases/vapors/mists with a water spray jet. Prevent fire extinguishing water from contaminating surface water or the ground water system.
NFPA 704
| HEALTH | 3 | Short exposure could cause serious temporary or moderate residual injury (e.g. liquid hydrogen, sulfuric acid, calcium hypochlorite, hexafluorosilicic acid) | |
| FIRE | 1 | Materials that require considerable preheating, under all ambient temperature conditions, before ignition and combustion can occur. Includes some finely divided suspended solids that do not require heating before ignition can occur. Flash point at or above 93.3 °C (200 °F). (e.g. mineral oil, ammonia) | |
| REACT | 1 | Normally stable, but can become unstable at elevated temperatures and pressures (e.g. propene) | |
| SPEC. HAZ. |
Personal precautions, protective equipment and emergency procedures
Advice for non-emergency personnel: Do not breathe vapors, aerosols. Avoid substance contact. Ensure adequate ventilation. Keep away from heat and sources of ignition.
Evacuate the danger area, observe emergency procedures, consult an expert. For personal protection see section 8.
Environmental precautions
Do not let product enter drains.
Methods and materials for containment and cleaning up
Cover drains. Collect, bind, and pump off spills. Observe possible material restrictions (see sections 7 and 10). Take up with liquid-absorbent and neutralising material (e.g. Chemizorb? OH ? , Merck Art. No. 101596). Dispose of properly. Clean up affected area.
Reference to other sections
For disposal see section 13.
Precautions for safe handling
Advice on protection against fire and explosion
Keep away from open flames, hot surfaces and sources of ignition.Take precautionary measures against static discharge.
Hygiene measures
Immediately change contaminated clothing. Apply preventive skin protection. Wash hands and face after working with substance.
For precautions see section 2.2.
Conditions for safe storage, including any incompatibilities
Storage conditions
Tightly closed.
Moisture sensitive. Store under inert gas.
Specific end use(s)
Apart from the uses mentioned in section 1.2 no other specific uses are stipulated
control parameter
Hazard composition and occupational exposure limitsExposure controls
Personal protective equipmentUse equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Tightly fitting safety goggles
This recommendation applies only to the product stated in the safety data sheet, supplied by us and for the designated use. When dissolving in or mixing with other substances and under conditions deviating from those stated in EN374 please contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell, Internet: www.kcl.de).
Full contact
Material: butyl-rubber
Minimum layer thickness: 0,7 mm Break through time: 480 min Material tested:Butoject? (KCL 898)
This recommendation applies only to the product stated in the safety data sheet, supplied by us and for the designated use. When dissolving in or mixing with other substances and under conditions deviating from those stated in EN374 please contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell, Internet: www.kcl.de).
Splash contact Material: Viton?
Minimum layer thickness: 0,7 mm Break through time: 30 min
Material tested:Vitoject? (KCL 890 / Aldrich Z677698, Size M)
protective clothing
required when vapours/aerosols are generated.
Our recommendations on filtering respiratory protection are based on the following standards: DIN EN 143, DIN 14387 and other accompanying standards relating to the used respiratory protection system.
Recommended Filter type: Filter type ABEK
The entrepeneur has to ensure that maintenance, cleaning and testing of respiratory protective devices are carried out according to the instructions of the producer.
These measures have to be properly documented.
Do not let product enter drains.
Information on basic physicochemical properties
- Appearancecolorless liquid, clear
- Odouramine-like
- Odour ThresholdNo data available
- pH11 at 20 g/l at 20 °C
- Melting point/freezing pointMelting point:< -70 °C
- Initial boiling point and boiling range 217 °C at 1.013 hPa - lit.
- Flash point93 °C - closed cup - DIN 51758
- Evaporation rateNo data available
- Flammability (solid, gas)No data available
- Upper/lower flammability or explosive limits Upper explosion limit: 4,5 %(V) Lower explosion limit: 0,8 %(V)
- Vapour pressure No data available
- Vapour density 7,64 - (Air = 1.0)
- Relative density0.942
- Water solubilityat 20 °C (decomposition)
- Partition coefficient: n-octanol/waterlog Pow: 0,31 - Bioaccumulation is not expected., (Lit.)
- Autoignition temperature 270 °C at 1.009,3 - 1.010,7 hPa
- Decomposition temperature>217 °C -
- ViscosityViscosity, kinematic: No data available Viscosity, dynamic: 2 mPa.s at 20 °C
- Explosive propertiesNo data available
- Oxidizing propertiesNo data available
Other safety information
Relative vapor density
7,64 - (Air = 1.0)
Reactivity
Forms explosive mixtures with air on intense heating.
A range from approx. 15 Kelvin below the flash point is to be rated as critical.
Chemical stability
The product is chemically stable under standard ambient conditions (room temperature) . May decompose on exposure to moist air or water.
Possibility of hazardous reactions
No data available
Conditions to avoid
Strong heating.
Incompatible materials
Strong oxidizing agents
Hazardous decomposition products
In the event of fire: see section 5
Information on toxicological effects
Acute toxicityLC50 Inhalation - Rat - male - 6 h - > 5 ppm (OECD Test Guideline 403)
LD50 Dermal - Rabbit - 4.290 mg/kg Remarks: (RTECS)
Result: Corrosive after 3 minutes to 1 hour of exposure - 1 h (OECD Test Guideline 404)
(Regulation (EC) No 1272/2008, Annex VI)
Result: Irreversible effects on the eye (OECD Test Guideline 405)
Remarks: (Regulation (EC) No 1272/2008, Annex VI) Causes serious eye damage.
(OECD Test Guideline 406)
Metabolic activation: with and without metabolic activation Result: negative
Remarks: (ECHA)
Test Type: In vitro mammalian cell gene mutation test Test system: Chinese hamster ovary cells
Metabolic activation: with and without metabolic activation Method: OECD Test Guideline 476
Result: negative
Test Type: Ames test
Test system: Salmonella typhimurium
Metabolic activation: with and without metabolic activation Method: OECD Test Guideline 471
Result: negative
Test Type: Mutagenicity (mammal cell test): chromosome aberration. Test system: Chinese hamster lung cells
Metabolic activation: with and without metabolic activation Method: OECD Test Guideline 473
Result: negative
Test Type: Micronucleus test Species: Mouse
Cell type: Red blood cells (erythrocytes) Application Route: Intraperitoneal Method: OECD Test Guideline 474 Result: negative
Toxicity
static test EC50 - Daphnia magna (Water flea) - 331 mg/l - 48 h (OECD Test Guideline 202)
1.000 mg/l - 72 h
(Directive 67/548/EEC, Annex V, C.3.)
Persistence and degradability
Biodegradability aerobic - Exposure time 28 d
Result: 67 % - Not biodegradable. (Directive 67/548/EEC Annex V, C.4.A.)
Bioaccumulative potential
Bioaccumulation Cyprinus carpio (Carp) - 8 Weeks
- 5 mg/l(Triethoxy(3-aminopropyl)silane)
Bioconcentration factor (BCF): 3,4 (OECD Test Guideline 305C)
Mobility in soil
No data available
Results of PBT and vPvB assessment
This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
Other adverse effects
No data available
Waste treatment methods
Product
See www.retrologistik.com for processes regarding the return of chemicals and containers, or contact us there if you have further questions.
UN number
ADR/RID: 2735 IMDG: 2735 IATA: 2735
UN proper shipping name
ADR/RID: AMINES, LIQUID, CORROSIVE, N.O.S. (Triethoxy(3-aminopropyl)silane) IMDG: AMINES, LIQUID, CORROSIVE, N.O.S. (Triethoxy(3-aminopropyl)silane) IATA: Amines, liquid, corrosive, n.o.s. (Triethoxy(3-aminopropyl)silane)
Transport hazard class(es)
ADR/RID: 8 IMDG: 8 IATA: 8
Packaging group
ADR/RID: II IMDG: II IATA: II
Environmental hazards
ADR/RID: no IMDG Marine pollutant: no IATA: no
Special precautions for user
No data available
Safety, health and environmental regulations/legislation specific for the substance or mixture
Regulations on the Safety Management of Hazardous ChemicalsAbbreviations and acronyms
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- CAS: Chemical Abstracts Service
- EC50: Effective Concentration 50%
- IATA: International Air Transportation Association
- IMDG: International Maritime Dangerous Goods
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- STEL: Short term exposure limit
- TWA: Time Weighted Average
References
【1】CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
【2】ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
【3】ECHA - European Chemicals Agency, website: https://echa.europa.eu/
【4】eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
【5】ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
【6】Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
【7】HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
【8】IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
【9】IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
【10】Sigma-Aldrich, website: https://www.sigmaaldrich.com/
The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.