2-ISOPROPOXYETHANOL
Product identifier
- Product name: 2-ISOPROPOXYETHANOL
- CBnumber: CB6175300
- CAS: 109-59-1
- EINECS Number: 203-685-6
- Synonyms: 2-Isopropoxyethanol,isopropyl glycol
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
- Uses advised against: none
Company Identification
- Company: Chemicalbook
- Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
- Telephone: 400-158-6606
Classification of the substance or mixture
Acute toxicity - Category 4, Dermal
Eye irritation, Category 2
Acute toxicity - Category 4, Inhalation
Label elements
Pictogram(s)
- Signal wordWarning
H226 Flammable liquid and vapour
H312 Harmful in contact with skin
H315 Causes skin irritation
H319 Causes serious eye irritation
H332 Harmful if inhaled
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P403+P235 Store in a well-ventilated place. Keep cool.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P264 Wash ... thoroughly after handling.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P271 Use only outdoors or in a well-ventilated area.
P302+P352 IF ON SKIN: Wash with plenty of water/...
P317 Get medical help.
P321 Specific treatment (see ... on this label).
P362+P364 Take off contaminated clothing and wash it before reuse.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
none
P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards
no data available
Substance
- Product name: 2-ISOPROPOXYETHANOL
- Synonyms: 2-Isopropoxyethanol,isopropyl glycol
- CAS: 109-59-1
- EC number: 203-685-6
- MF: C5H12O2
- MW: 104.15
Description of first aid measures
If inhaledFresh air, rest.
Remove contaminated clothes. Rinse skin with plenty of water or shower.
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Rinse mouth. Give one or two glasses of water to drink.
Most important symptoms and effects, both acute and delayed
May be harmful by inhalation, ingestion or skin absorption. May cause skin and eye irritation. (USCG, 1999)
Indication of any immediate medical attention and special treatment needed
Minimum/Potential Fatal Human Dose3. 3= moderately toxic: probable oral lethal dose (human) 0.5-5 g/kg, between 1 oz & 1 pint (or 1 lb) for 70 kg person (150 lb). ethylene glycol alkyl (and aryl) ethers
The material may readily be absorbed through the intact skin...
Extinguishing media
Alcohol" foam. water may be ineffective
Specific Hazards Arising from the Chemical
Special Hazards of Combustion Products: Emits toxic fumes when heated upon decomposition. (USCG, 1999)
Advice for firefighters
Use water spray, powder, foam, carbon dioxide. In case of fire: keep drums, etc., cool by spraying with water.
NFPA 704
| HEALTH | 1 | Exposure would cause irritation with only minor residual injury (e.g. acetone, sodium bromate, potassium chloride) | |
| FIRE | 3 | Liquids and solids (including finely divided suspended solids) that can be ignited under almost all ambient temperature conditions . Liquids having a flash point below 22.8 °C (73 °F) and having a boiling point at or above 37.8 °C (100 °F) or having a flash point between 22.8 and 37.8 °C (73 and 100 °F). (e.g. gasoline, acetone) | |
| REACT | 0 | Normally stable, even under fire exposure conditions, and is not reactive with water (e.g. helium,N2) | |
| SPEC. HAZ. |
Personal precautions, protective equipment and emergency procedures
Personal protection: filter respirator for organic gases and vapours adapted to the airborne concentration of the substance. Remove all ignition sources. Ventilation. Collect leaking and spilled liquid in sealable containers as far as possible.
Environmental precautions
Personal protection: filter respirator for organic gases and vapours adapted to the airborne concentration of the substance. Remove all ignition sources. Ventilation. Collect leaking and spilled liquid in sealable containers as far as possible.
Methods and materials for containment and cleaning up
Collect and arrange disposal. Keep the chemical in suitable and closed containers for disposal. Remove all sources of ignition. Use spark-proof tools and explosion-proof equipment. Adhered or collected material should be promptly disposed of, in accordance with appropriate laws and regulations.
Precautions for safe handling
NO open flames, NO sparks and NO smoking. Above 44°C use a closed system, ventilation and explosion-proof electrical equipment. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Cool. Fireproof. Separated from strong oxidants.SEE ETHERS. ETHERS SHOULD NOT BE STORED NEAR POWERFUL OXIDIZERS OR IN AREAS OF HIGH FIRE HAZARD. THEY SHOULD BE KEPT COOL AND THE CONTAINERS ELECTRICALLY GROUNDED TO AVOID SPARKS. ETHERS
Control parameters
Occupational Exposure limit valuesTLV: 25 ppm as TWA; (skin).MAK: 43 mg/m3, 10 ppm; peak limitation category: I(2); skin absorption (H); pregnancy risk group: C
no data available
Exposure controls
Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.
Individual protection measures
Eye/face protectionWear safety goggles.
Protective gloves. Protective clothing.
Use ventilation, local exhaust or breathing protection.
no data available
Information on basic physicochemical properties
- Physical stateLiquid
- Colour
Colourless.
- Odour
MILD ETHEREAL ODOR
- Melting point/freezing point
-74.57°C. Atm. press.:1 atm.
- Boiling point or initial boiling point and boiling range
145 °C. Atm. press.:1 atm. Remarks:Experimentally derived value.;146.7 °C. Atm. press.:1 atm. Remarks:Value from EPIEB MPBPWIN v1.43 QSAR for predicting boiling point using adapted Stein and Brown method.
- Flammability
Class IC Flammable Liquid: Fl.P. at or above 73°F and below 100°F.
- Lower and upper explosion limit/flammability limit1.6-13.0%(V)
- Flash point
> 43 - < 45 °C. Atm. press.:101.76 kPa.
- Auto-ignition temperature
240 °C. Atm. press.:1 atm.
- Decomposition temperature
no data available
- pH
no data available
- Kinematic viscosity
kinematic viscosity (in mm2/s) = 2.7. Temperature:20°C.;kinematic viscosity (in mm2/s) = 1.84. Temperature:40°C.
- Solubility>100g/l soluble
- Partition coefficient n-octanol/water
log Pow = 0.43. Temperature:20 °C.
- Vapour pressure5.99 hPa (25 °C)
- Density and/or relative density
903 kg/m3. Temperature:20 °C.
- Relative vapour density
3.6 (AIR= 1)
- Particle characteristics
no data available
Reactivity
The substance can presumably form explosive peroxides. Reacts violently with strong oxidants.
Chemical stability
VOLATILE
Possibility of hazardous reactions
MODERATE; CAN REACT WITH OXIDIZING MATERIALSETHYLENE GLYCOL ISOPROPYL ETHER acts both as an alcohol and ether. May react violently with strong oxidizing agents. May generate flammable and/or toxic gases with alkali metals, nitrides, and other strong reducing agents. May initiate the polymerization of isocyanates and epoxides.
Conditions to avoid
no data available
Incompatible materials
Oxidizers.
Hazardous decomposition products
no data available
Acute toxicity
- Oral: LD50 - rat (male) - 3 089 mg/kg bw. Remarks:Results for fasted animals.
- Inhalation: NOAEL: Reduction on testis weight - rat (male) - > 3 500 ppm.
- Dermal: LD50 - rabbit (male) - 1 337 mg/kg bw.
Skin corrosion/irritation
no data available
Serious eye damage/irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
Carcinogenicity
no data available
Reproductive toxicity
no data available
STOT-single exposure
The substance is irritating to the eyes. The substance is mildly irritating to the skin and respiratory tract.
STOT-repeated exposure
The substance may have effects on the blood. This may result in anaemia.
Aspiration hazard
A harmful contamination of the air will be reached rather slowly on evaporation of this substance at 20°C.
Toxicity
- Toxicity to fish: LC50 - Oryzias latipes - > 100 mg/L - 96 h.
- Toxicity to daphnia and other aquatic invertebrates: LC50 - Daphnia magna - > 970 mg/L - 48 h.
- Toxicity to algae: EC50 - 440 mg/L - 96 h.
- Toxicity to microorganisms: EC10 - Pseudomonas putida - 4 600 mg/L - 16 h.
Persistence and degradability
no data available
Bioaccumulative potential
no data available
Mobility in soil
no data available
Other adverse effects
no data available
Disposal methods
ProductThe material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
UN Number
ADR/RID: UN3271 (For reference only, please check.)
IMDG: UN3271 (For reference only, please check.)
IATA: UN3271 (For reference only, please check.)
UN Proper Shipping Name
ADR/RID: ETHERS, N.O.S. (For reference only, please check.)
IMDG: ETHERS, N.O.S. (For reference only, please check.)
IATA: ETHERS, N.O.S. (For reference only, please check.)
Transport hazard class(es)
ADR/RID: 3 (For reference only, please check.)
IMDG: 3 (For reference only, please check.)
IATA: 3 (For reference only, please check.)
Packing group, if applicable
ADR/RID: II (For reference only, please check.)
IMDG: II (For reference only, please check.)
IATA: II (For reference only, please check.)
Environmental hazards
ADR/RID: No
IMDG: No
IATA: No
Special precautions for user
no data available
Transport in bulk according to IMO instruments
no data available
Safety, health and environmental regulations specific for the product in question
European Inventory of Existing Commercial Chemical Substances (EINECS)Abbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
- IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
- HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
- IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
- eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
- CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
- ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
- ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
- Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
- ECHA - European Chemicals Agency, website: https://echa.europa.eu/
The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.