1-Methylpyrrolidine
Product identifier
- Product name: 1-Methylpyrrolidine
- CBnumber: CB0672357
- CAS: 120-94-5
- EINECS Number: 204-438-5
- Synonyms: N-Methylpyrrolidine,1-METHYLPYRROLIDINE
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
- Uses advised against: none
Company Identification
- Company: Chemicalbook
- Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
- Telephone: 400-158-6606
GHS Label elements, including precautionary statements
-
Symbol(GHS)
- Signal wordDanger
Substance
- Product name: 1-Methylpyrrolidine
- Synonyms: N-Methylpyrrolidine,1-METHYLPYRROLIDINE
- CAS: 120-94-5
- EC number: 204-438-5
- MF: C5H11N
- MW: 85.15
Description of first aid measures
General adviceMost important symptoms and effects, both acute and delayed
Indication of any immediate medical attention and special treatment needed
Extinguishing media
Suitable extinguishing mediaSpecial hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx)
Advice for firefighters
Wear self-contained breathing apparatus for firefighting if necessary.
Further information
Use water spray to cool unopened containers.
NFPA 704
| HEALTH | |||
| FIRE | 3 | Liquids and solids (including finely divided suspended solids) that can be ignited under almost all ambient temperature conditions . Liquids having a flash point below 22.8 °C (73 °F) and having a boiling point at or above 37.8 °C (100 °F) or having a flash point between 22.8 and 37.8 °C (73 and 100 °F). (e.g. gasoline, acetone) | |
| REACT | 1 | Normally stable, but can become unstable at elevated temperatures and pressures (e.g. propene) | |
| SPEC. HAZ. |
Personal precautions, protective equipment and emergency procedures
Wear respiratory protection. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Remove all sources of ignition. Evacuate personnel to safe areas. Beware of vapours accumulating to form explosive concentrations. Vapours can accumulate in low areas.
For personal protection see section 8.
Environmental precautions
Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided.
Methods and materials for containment and cleaning up
Contain spillage, and then collect with non-combustible absorbent material, (e.g. sand, earth, diatomaceous earth, vermiculite) and place in container for disposal according to local / national regulations (see section 13).
Reference to other sections
For disposal see section 13.
Precautions for safe handling
Avoid contact with skin and eyes. Avoid inhalation of vapour or mist.
Keep away from sources of ignition - No smoking.Take measures to prevent the build up of electrostatic charge.
For precautions see section 2.2.
Conditions for safe storage, including any incompatibilities
Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage. Store in cool place.
Specific end use(s)
Apart from the uses mentioned in section 1.2 no other specific uses are stipulated
control parameter
Hazard composition and occupational exposure limitsExposure controls
Appropriate engineering controlsAvoid contact with skin, eyes and clothing. Wash hands before breaks and immediately after handling the product.
Tightly fitting safety goggles. Faceshield (8-inch minimum). Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands.
The selected protective gloves have to satisfy the specifications of Regulation (EU) 2016/425 and the standard EN 374 derived from it.
Splash contact Material: Nitrile rubber
Minimum layer thickness: 0,4 mm Break through time: 55 min
Material tested:Camatril? (KCL 730 / Aldrich Z677442, Size M)
data source: KCL GmbH, D-36124 Eichenzell, phone +49 (0)6659 87300, e-mail sales@kcl.de, test method: EN374
If used in solution, or mixed with other substances, and under conditions which differ from EN 374, contact the supplier of the CE approved gloves. This recommendation is advisory only and must be evaluated by an industrial hygienist and safety officer familiar with the specific situation of anticipated use by our customers. It should not be construed as offering an approval for any specific use scenario.
Complete suit protecting against chemicals, Flame retardant antistatic protective clothing., The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Where risk assessment shows air-purifying respirators are appropriate use a full- face respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls. If the respirator is the sole means of protection, use a full-face supplied air respirator. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided.
Information on basic physicochemical properties
- Appearancecolourless liquid
- Odouramine-like
- Odour ThresholdNo data available d) pH 12,3 at 10,2 g/l at 20 °C Melting point/freezing point Initial boiling point and boiling range Melting point:< -80 °C 76 - 80 °C Flash point -18 °C - closed cup - Regulation (EC) No. 440/2008, Annex, A.9 Evaporation rate No data available Flammability (solid, gas) Upper/lower flammability or explosive limits No data available Upper explosion limit: 9,1 %(V) Lower explosion limit: 1,1 %(V) Vapour pressure 107,46 hPa at 20 °C - OECD Test Guideline 104 Vapour density 2,94 Relative density 0,8 g/mL at 20 °C - Water solubility completely miscible Partition coefficient: n-octanol/water Autoignition temperature Decomposition temperature log Pow: 1,1 at 23 °C - OECD Test Guideline 117 - Bioaccumulation is not expected. 180 °C at 1.013,25 hPa No data available Viscosity No data available Explosive properties No data available Oxidizing properties No data available
- Melting point/freezing pointMelting point:< -80 °C
- Initial boiling point and boiling range76 - 80 °C
- Flash point-18 °C - closed cup - Regulation (EC) No. 440/2008, Annex, A.9
- Evaporation rate−7 °F
- Flammability (solid, gas)No data available
- Upper/lower flammability or explosive limits Upper explosion limit: 9,1 %(V) Lower explosion limit: 1,1 %(V)
- Vapour pressure107,46 hPa at 20 °C - OECD Test Guideline 104
- Vapour density2,94
- Relative density0,8 g/mL at 20 °C -
- Water solubilitycompletely miscible
- Partition coefficient: n-octanol/waterlog Pow: 1,1 at 23 °C - OECD Test Guideline 117 - Bioaccumulation is not expected.
- Autoignition temperature 180 °C at 1.013,25 hPa
- Decomposition temperature No data available
- ViscosityNo data available
- Explosive propertiesNo data available
- Oxidizing propertiesNo data available
Other safety information
Relative vapour density
2,94
Reactivity
No data available
Chemical stability
Stable under recommended storage conditions.
Possibility of hazardous reactions
No data available
Conditions to avoid
Heat, flames and sparks.
Incompatible materials
Strong acids, Strong oxidizing agents
Hazardous decomposition products
Hazardous decomposition products formed under fire conditions. - Carbon oxides, Nitrogen oxides (NOx)
Other decomposition products - No data available In the event of fire: see section 5
Information on toxicological effects
Acute toxicityLC50 Inhalation - Rat - male and female - 4 h - 1,1 - 2,5 mg/l (OECD Test Guideline 403)
Result: Corrosive - 1 h (OECD Test Guideline 405) Causes serious eye damage.
Escherichia coli/Salmonella typhimurium Result: negative
Acute oral toxicity - If ingested, severe burns of the mouth and throat, as well as a danger of perforation of the oesophagus and the stomach.
To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.
Toxicity
(OECD Test Guideline 203)
static test EC50 - Daphnia magna (Water flea) - 7,29 mg/l - 48 h (Directive 67/548/EEC, Annex V, C.2.)
(OECD Test Guideline 201)
static test EC10 - Pseudokirchneriella subcapitata (green algae) - 69,07 mg/l - 72 h
(OECD Test Guideline 201)
Persistence and degradability
Biodegradability aerobic - Exposure time 10 d
Result: 98 % - Readily biodegradable. (OECD Test Guideline 302B)
Biochemical Oxygen Demand (BOD)
Chemical Oxygen Demand (COD)
< 2 mg/g
Remarks: (External MSDS)
1.880 mg/g
Remarks: (External MSDS)
Bioaccumulative potential
No data available
Mobility in soil
No data available
Results of PBT and vPvB assessment
This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
Other adverse effects
Toxic to aquatic life with long lasting effects.
Additional ecological information
No data available
Waste treatment methods
Product
Offer surplus and non-recyclable solutions to a licensed disposal company. Waste material must be disposed of in accordance with the Directive on waste 2008/98/EC as well as other national and local regulations. Leave chemicals in original containers. No mixing with other waste. Handle uncleaned containers like the product itself.
Contaminated packaging
Dispose of as unused product.
UN number
ADR/RID: 3286 IMDG: 3286 IATA: 3286
UN proper shipping name
ADR/RID: FLAMMABLE LIQUID, TOXIC, CORROSIVE, N.O.S. (1-Methylpyrrolidine) IMDG: FLAMMABLE LIQUID, TOXIC, CORROSIVE, N.O.S. (1-Methylpyrrolidine)
IATA: Flammable liquid, toxic, corrosive, n.o.s. (1-Methylpyrrolidine)
Transport hazard class(es)
ADR/RID: 3 (6.1, 8) IMDG: 3 (6.1, 8) IATA: 3 (6.1)(8)
Packaging group
ADR/RID: II IMDG: II IATA: II
Environmental hazards
ADR/RID: yes IMDG Marine pollutant: yes IATA: no
Special precautions for user
No data available
Safety, health and environmental regulations/legislation specific for the substance or mixture
Regulations on the Safety Management of Hazardous ChemicalsAbbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
【1】CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
【2】ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
【3】ECHA - European Chemicals Agency, website: https://echa.europa.eu/
【4】eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
【5】ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
【6】Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
【7】HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
【8】IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
【9】IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
【10】Sigma-Aldrich, website: https://www.sigmaaldrich.com/
The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.