天堂网亚洲,天天操天天搞,91视频高清,菠萝蜜视频在线观看入口,美女视频性感美女视频,95丝袜美女视频国产,超高清美女视频图片

ChemicalBook >> journal list >> Polyhedron >>article
Polyhedron

Polyhedron

IF: 2.39
Download PDF

Synthesis, spectroscopy and X-ray crystal structures of some zinc(II) and cadmium(II) complexes of the 2-pyridinecarboxaldehyde Schiff bases of S-methyl- and S-benzyldithiocarbazates

Published:28 May 2014 DOI: 10.1016/j.poly.2014.02.016
Aminul Huq Mirza , Malai Haniti S.A. Hamid , Sazwani Aripin , Mohammad Rezaul Karim , Md. Arifuzzaman , Mohammad Akbar Ali , Paul V. Bernhardt

Abstract

The Schiff bases formed by condensation of S-methyl- and S-benzyldithiocarbazate with 2-pyridinecarboxaldehyde react with zinc(II) and cadmium(II) acetates to form stable metal complexes of general formulas, [Zn(NNS)(CH3COO)]2 and [M(NNS)2] (M?=?Zn2+, Cd2+; NNS??=?anionic forms of the 2-pyridinecarboxaldenhdye Schiff bases of S-methyl- and S-benzyldithiocarbazate, respectively) which have been characterized by a variety of physico-chemical techniques and X-ray crystallographic structure analysis. The complexes, [Zn(NNS)(CH3COO)]2 are acetate anion-bridged centrosymmetric dimers in which each of the Schiff bases is coordinated to the zinc(II) ions as a uninegatively charged NNS tridentate chelating agent coordinating via the pyridine nitrogen atom, the azomethine nitrogen atom and the thiolate sulfur atom. The acetate anion acts as a bridging bidentate ligand coordinating with the two zinc atoms in a synsyn manner. Each zinc(II) ion in the dimer adopts an approximately square-pyramidal geometry. The bis-ligand complexes, [M(NNS)2] (M?=?Zn2+, Cd2+) have distorted octahedral structures in which the two anionic Schiff bases are coordinated to the metal ions meridionally as NNS tridentate chelating agents via the pyridine nitrogen atom, the azomethine nitrogen atom and the thiolate sulfur atom.

Both the mono- and bis-ligand zinc(II) complexes exhibit strong cytotoxic activity against the HELA (human cervical cancer) cell lines. Some of these compounds exhibit stronger cytotoxicity against HELA than the commercially important anticancer drug, Tamoxifen.

Substances (6)

Related products

Similar articles

IF:4.3

Spectroscopic and biological approach of Ni(II) and Cu(II) complexes of 2-pyridinecarboxaldehyde thiosemicarbazone

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy Sulekh Chandra , Smriti Raizada ,etc Published: 1 March 2008
IF:4.4

Antimicrobial and anticancer insights of cinnamaldehyde Schiff bases and metal complexes

Inorganic Chemistry Communications Neetu Singh, Surender Singh Yadav,etc Published: 13 June 2024