天堂网亚洲,天天操天天搞,91视频高清,菠萝蜜视频在线观看入口,美女视频性感美女视频,95丝袜美女视频国产,超高清美女视频图片

ChemicalBook >> journal list >> Phytotherapy Research >>article
Phytotherapy Research

Phytotherapy Research

IF: 6.09
Download PDF

Emodin: A Review of its Pharmacology, Toxicity and Pharmacokinetics.

Published:1 August 2016 DOI: 10.1002/ptr.5631 PMID: 27188216
Xiaoxv Dong,?Jing Fu,?Xingbin Yin,?Sali Cao,?Xuechun Li,?Longfei Lin,?Jian Ni

Abstract

Emodin is a natural anthraquinone derivative that occurs in many widely used Chinese medicinal herbs, such as Rheum palmatum, Polygonum cuspidatum and Polygonum multiflorum. Emodin has been used as a traditional Chinese medicine for over 2000?years and is still present in various herbal preparations. Emerging evidence indicates that emodin possesses a wide spectrum of pharmacological properties, including anticancer, hepatoprotective, antiinflammatory, antioxidant and antimicrobial activities. However, emodin could also lead to hepatotoxicity, kidney toxicity and reproductive toxicity, particularly in high doses and with long-term use. Pharmacokinetic studies have demonstrated that emodin has poor oral bioavailability in rats because of its extensive glucuronidation. This review aims to comprehensively summarize the pharmacology, toxicity and pharmacokinetics of emodin reported to date with an emphasis on its biological properties and mechanisms of action. Copyright ? 2016 John Wiley & Sons, Ltd.

Substances (1)

Related products
Procduct Name CAS Molecular Formula Supplier Price
Emodin 518-82-1 C15H10O5 600 suppliers $29.00-$1375.00

Similar articles

IF:6.1

Andrographolide: A review of its pharmacology, pharmacokinetics, toxicity and clinical trials and pharmaceutical researches.

Phytotherapy Research Bin Zeng, Ailing Wei,etc Published: 1 January 2022
IF:2.4

Azelastine hydrochloride: a review of pharmacology, pharmacokinetics, clinical efficacy and tolerability.

Current Medical Research and Opinion Jonathan A Bernstein,etc Published: 1 October 2007