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Archives of Gynecology and Obstetrics

Archives of Gynecology and Obstetrics

IF: 2.1
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Depot-medroxyprogesterone acetate: an update

Published:10 May 2008 DOI: 10.1007/s00404-007-0497-z PMID: 18470526
Sayed Bakry, Zaher O. Merhi, Trudy J. Scalise, Mohamad S. Mahmoud, Ahmed Fadiel, Frederick Naftolin

Abstract

Objective

Depo-Provera? is a contraceptive approved by the US Food and Drug Administration (FDA) since 1992 and used worldwide by more than 90 million women.

Aim of study

Despite the fact that progestins are endogenous hormones that are secreted by the body, its excess might lead to detrimental health effects. Whether progestins as contraceptives are friends or foes is a questionable matter. In this manuscript, we drive the attention to both usage and side effects Depo-Provera.

Results

Depot-medroxyprogesterone acetate (DMPA) is a highly effective, convenient non-daily hormonal contraceptive option that has been available worldwide for many years. The experience with DMPA provides a large body of long-term data regarding the efficacy and safety of this contraceptive method; this long-term experience has established that the use of DMPA does not increase the risk of cardiovascular events, breast cancer, other gynecologic malignancy, or postmenopausal fracture; however, patients are often more concerned about the relatively immediate effects of contraceptives such as potential changes in menstrual cycle, body weight, and mood disturbances.

Conclusion

Concerns about such issues may lead to reluctance to initiate therapy or premature discontinuation. Counseling and understanding of women’s concerns and experiences using Depo-Provera is important and could help health care providers redesign counseling strategies to improve contraceptive continuation and improve patient adherence.

Substances (2)

Related products
Procduct Name CAS Molecular Formula Supplier Price
Medroxyprogesterone Acetate 71-58-9 C24H34O4 571 suppliers $49.00-$1440.00
2,2-Bis(hydroxymethyl)propionic acid 4767-03-7 C5H10O4 483 suppliers $6.00-$4084.08

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