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?BSP Antibody
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Cat#：PL0402144
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Isotype:Rabbit Polyclonal IgG
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Immunogen：peptide corresponding to a sequence at the N-terminus of human Bone Sialoprotein.?
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Purification:?Immunogen affinity purified
Storage Buffer:?PBS, pH 7.4(1%BSA and 0.1% Sodium azide)
Background：
BSP is also known as IBSP(integrin-binding sialoprotein). The protein encoded by this gene is a major structural protein of the bone matrix. Bone sialoprotein is an acidic glycoprotein of approximately 70 kD that undergoes extensive posttranslational modifications. It constitutes approximately 12% of the noncollagenous proteins in human bone and is synthesized by skeletal-associated cell types, including hypertrophic chondrocytes, osteoblasts, osteocytes, and osteoclasts. The only extraskeletal site of its synthesis is the trophoblast. This protein binds to calcium and hydroxyapatite via its acidic amino acid clusters, and mediates cell attachment through an RGD sequence that recognizes the vitronectin receptor.
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Alternate Names：
BNSP antibody;Bone sialoprotein 2 antibody;Bone sialoprotein 2 precursor antibody;Bone sialoprotein II antibody;bone sialoprotein II; bone sialoprotein antibody;BSP antibody;BSP II antibody.?
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Specificity Reaction：Hu，Mo，Rat
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Application Notes:WB: 1:100-500 IHC: 1:500-1000
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Storage ：
Store at –20oC for one year. Avoid repeated freeze-thaw cycles. At 4oC for 2-3 weeks after reconstituted.
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This product for research use only, not for use in humans, therapeutic or diagnostic procedures.
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