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?ASIC3 Antibody
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Cat#:PL0305941
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Isotype:Rabbit Polyclonal IgG
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Immunogen:Peptide derived from human ASIC3.?
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Purification:?Immunogen affinity purified
Storage Buffer:?PBS, pH 7.4(1%BSA and 0.1% Sodium azide)
Background:
Cation channel with high affinity for sodium, which is gated by extracellular protons and inhibited by the diuretic amiloride. Generates a biphasic current with a fast inactivating and a slow sustained phase. In sensory neurons is proposed to mediate the pain induced by acidosis that occurs in ischemic, damaged or inflamed tissue. May be involved in hyperalgesia.
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Alternate Names:
ASICs3; ACCN3; ASIC3_HUMAN; Acid-sensing ion channel 3; Amiloride sensitive cation channel 3; Amiloride sensitive cation channel 3 testis; Amiloride-sensitive cation channel 3; ASIC3; DRASIC; hASIC3; hTNaC1; Modulatory subunit of ASIC 2a; Modulatory subunit of ASIC2a; Neuronal amiloride sensitive cation channel 3; Neuronal amiloride-sensitive cation channel 3; Proton gated cation channel subunit; SLNAC1; Testis sodium channel 1; TNaC1. ?
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Specificity Reaction:Hu, Mo, Rat, Pig, Hor
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Application Notes:WB: 1:100-500 E: 1:500-1000 IHC: 1:100-500 IF: 1:100-500 FC: 1:100-500
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Storage :
Store at –20oC for one year. Avoid repeated freeze-thaw cycles. At 4oC for 2-3 weeks after reconstituted.
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This product for research use only, not for use in humans, therapeutic or diagnostic procedures.
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