Mycophenolic acid 霉酚酸 麥可酚酸
Mycophenolic acid
Mycophenolic acid
M3536 - powder, BioReagent, suitable for cell culture, ≥98%
CAS:24280-93-1
分子式:C17H20O6
分子量:320.3
外觀:白色,乳白色粉末
純度:>;=98%
溶解性:溶于甲醇,乙醇;微溶于醚,氯仿;難溶于苯,甲苯;幾乎不溶于冷水。
儲存: 4℃保存5年
用途:來源于Penicillium stoloniferum及類似菌株的一類抗生素/抗菌藥。能在體內(nèi)通過抑制次黃〔嘌呤核〕苷酸脫氫酶的作用阻斷嘌呤核苷酸的合成。阻止T細胞,淋巴細胞的分裂及B細胞中抗體的形成從而作為一種免疫抑制因子。在分子生物學中用于篩選含大腸桿菌黃嘌呤鳥嘌呤磷酸核糖轉(zhuǎn)移酶基因的細胞。
參考資料:
霉酚酸
M3536-50MG 981.63 SIGMA原裝北京現(xiàn)貨銷售
M3536-250MG 3,383.64 SIGMA原裝北京現(xiàn)貨銷售
別名: 6-(1,3-Dihydro-7-hydroxy-5-methoxy-4-methyl-1-oxoisobenzofuran-6-yl)-4-methyl-4-hexanoic acid, 6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoic acid,麥可酚酸
溶解:
methanol: soluble50 mg/mL (Stock solutions should be stored at 2-8°C.)
Application
Recommended for use as a selection agent at 25 μg/ml.
Used to select animal cells expressing the Escherichia coli gene for xanthine-guanine phosphosribosyl transferase.
Biochem/physiol Actions
Immunosuppressive agent. Suppresses cytokine-induced nitric oxide production.
Immunosuppressive agent. Used to inhibit early stage biosynthesis of purine nucleotides. Used as a specific inhibitor of inosine 5′-monophosphate (IMP) dehydrogenase (IMPDH) and inducer of IMP dehydrogenase gene expression.
Mode of Action: Blocks inosine monophosphate dehydrogenase in the guanosine monophosphate pathway.
關(guān)鍵字: 霉酚酸;Mycophenolic acid;24280-93-1;M3536;SIGMA
我公司位于北京市海淀區(qū)。。。