價格 | ¥17400 |
包裝 | 1mg |
最小起訂量 | 1mg |
發(fā)貨地 | 上海 |
更新日期 | 2024-12-02 |
中文名稱:CXCL4, Human, 重組蛋白 (His) | 英文名稱:CXCL4 Protein, Human, Recombinant (His) |
品牌: TargetMol | 產地: 美國 |
保存條件: store at low temperature | Shipping with blue ice. | 純度規(guī)格: Greater than 95% as determined by reducing SDS-PAGE. |
產品類別: 抑制劑 | |
貨號: TMPJ-00012 |
名稱 | CXCL4 Protein, Human, Recombinant (His) |
描述 | Human Chemokine (C-X-C motif) Ligand 4 (CXCL4) is expressed in megakaryocytes and stored in the alpha-granules of platelets. CXCL4 contains several heparin-binding sites at the C-terminal region and binds heparin with high affinity. The active CXCL4 protein is a tetramer. Human and mouse CXCL4 share 64% sequence identity. CXCL4 is chemotactic for neutrophils, fibroblasts and monocytes and plays a critical role in inflammation and wound repair. CXCL4 functions via a splice variant of the chemokine receptor CXCR3, known as CXCR3B. The major physiologic role of CXCL4 appears to be neutralization of heparin-like molecules on the endothelial surface of blood vessels, thereby inhibiting local antithrombin III activity and promoting coagulation. In contrast to other CXC chemokines, CXCL4 lacks chemotactic activity for polymorphonuclear granulocytes. |
體外活性 | Testing in progress |
體內活性 | Testing in progress |
存儲條件 | store at low temperature | Shipping with blue ice. |
關鍵字 | SCYB-4 | CXCL 4 | CXCL-4 | SCYB 4 | PF 4 |
成立日期 | 2013-04-18 (12年) | 注冊資本 | 589.8595萬人民幣 |
員工人數 | 100-500人 | 年營業(yè)額 | ¥ 1億以上 |
主營行業(yè) | 中間體,天然產物,生物化工,化學試劑,生物技術服務 | 經營模式 | 貿易,工廠,試劑,定制,服務 |
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