CXCL4產(chǎn)品信息
英文名稱:Platelet factor 4
中文名稱:血小板因子4
靶點(diǎn)別稱:PF-4,C-X-C motif chemokine 4,CXCL4
物種:Human
屬性:Protein
標(biāo)記:Unconjugated
內(nèi)毒素(Endotoxin)
Less than 1.0 EU per μg by the LAL method.
純度(Purity)
>95% as determined by SDS-PAGE.
制劑(Formulation)
Lyophilized from 0.22 μm filtered solution in 10 mM Sodium Citrate,150 mM NaCl,pH5.0 with trehalose as protectant.
Contact us for customized product form or formulation.
重構(gòu)方法(Reconstitution)
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
存儲(chǔ)(Storage)
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20°C to -70°C for 12 months in lyophilized state;
-70°C for 3 months under sterile conditions after reconstitution.
CXCL4分子背景
CXCL4或血小板因子4(PF4)是屬于CXC趨化因子家族的一種小細(xì)胞因子。這種趨化因子以同源四聚體的形式從活化血小板的α顆粒中釋放出來,對(duì)肝素具有高親和力,并參與血小板聚集。CXCL4對(duì)中性粒細(xì)胞和單核細(xì)胞具有趨化性,同時(shí)也是造血、血管生成和T細(xì)胞功能的抑制劑。CXCL4/PF4在人肝纖維化中上調(diào),并通過介導(dǎo)星狀細(xì)胞增殖、遷移和肝內(nèi)免疫細(xì)胞募集在實(shí)驗(yàn)性肝纖維化中發(fā)揮非冗余的功能作用。
關(guān)鍵字: CXCL4;CXCL4蛋白;血小板因子4;ACRO;百普賽斯;
百普賽斯集團(tuán)ACROBiosystems Group(股票代碼:301080)是成立于2010年的跨國(guó)生物科技公司,是為全球生物醫(yī)藥、健康產(chǎn)業(yè)領(lǐng)域提供關(guān)鍵生物試劑產(chǎn)品及解決方案的行業(yè)平臺(tái)型基石企業(yè)。2021年在創(chuàng)業(yè)板上市。百普賽斯集團(tuán)業(yè)務(wù)遍布全球,橫跨亞洲、北美洲、歐洲,在中國(guó)、美國(guó)、瑞士等12個(gè)城市設(shè)有辦公室、研發(fā)中心及生產(chǎn)基地。目前累計(jì)服務(wù)客戶超6000家,與全球Top 20醫(yī)藥企業(yè)均建立了長(zhǎng)期、穩(wěn)定的合作伙伴關(guān)系。集團(tuán)旗下?lián)碛衅放艫CROBiosystems百普賽斯、bioSeedin柏思薈、Condense Capital墾拓資本和ACRODiagnostics百斯醫(yī)學(xué)等。