
維百奧生物庫(kù)存現(xiàn)貨,特價(jià)銷售Human IL-13 Recombinant Protein 2ug!
| 產(chǎn)品信息
品名:Human IL-13 Recombinant Protein
品牌:Peprotech
貨號(hào):200-13-2ug
規(guī)格:2ug
| 產(chǎn)品屬性
種屬 | Human | 形式 | Lyophilized |
Expression System | E. coli | 純化類型 | purified |
分子量 | 12.6 kDa | 內(nèi)含物 | no preservative |
內(nèi)毒素濃度 | <1 EU/μg | 保存條件 | -20°C |
偶聯(lián)物 | Unconjugated | 運(yùn)輸條件 | Ambient |
已發(fā)表種屬 | Human, Mouse, Non-human primate, Pig, Rat |
純度 | ≥ 98% by SDS-PAGE gel and HPLC analyses. |
氨基酸序列 | MSPGPVPPST ALRELIEELV NITQNQKAPL CNGSMVWSIN LTAGMYCAAL ESLINVSGCS AIEKTQRMLS GFCPHKVSAG QFSSLHVRDT KIEVAQFVKD LLLHLKKLFR EGRFN |
活性 | The ED50 as determined by the dose-dependent proliferation of TF-1 cells was ≤ 1.0 ng/ml, corresponding to a specific activity of ≥ 1 x 10^6 units/mg. |
| 產(chǎn)品描述
Recombinant HumanIL-13 is a 12.6 kDa protein consisting of 115 amino acid residues.
| 耙標(biāo)信息
IL-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells, and is involved in regulating inflammatory and immune responses. IL-13 down-regulates macrophage activity, thereby inhibiting the production of pro-inflammatory cytokines and chemokines, and is involved in allergen-induced asthma through mechanisms independent of IgE and eosinophils. IL-13 also regulates several stages of B cell maturation and differentiation, up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. Structurally, IL-13 closely resembles IL-3, IL-4, IL-5 and GM-CSF. The gene encoding IL-13, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with the IL-13 gene particularly close to IL4.
關(guān)鍵字: IL-13;PeproTech;
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