
維百奧生物庫存現(xiàn)貨,特價銷售Human IL-4 Recombinant Protein 50ug!
| 產(chǎn)品信息
品名:Human IL-4 Recombinant Protein
品牌:Peprotech
貨號:200-04-50ug
規(guī)格:50ug
| 產(chǎn)品屬性
種屬 | Human | 形式 | Lyophilized |
Expression System | E. coli | 純化類型 | purified |
分子量 | 15.1 kDa | 內(nèi)含物 | no preservative |
內(nèi)毒素濃度 | <1 EU/μg | 保存條件 | -20°C |
偶聯(lián)物 | Unconjugated | 運輸條件 | Ambient |
已發(fā)表種屬 | Chicken, Dog, Human, Mouse, Pig, Rabbit, Rat |
純度 | ≥ 98% by SDS-PAGE gel and HPLC analyses. |
氨基酸序列 | MHKCDITLQE IIKTLNSLTE QKTLCTELTV TDIFAASKNT TEKETFCRAA TVLRQFYSHH EKDTRCLGAT AQQFHRHKQL IRFLKRLDRN LWGLAGLNSC PVKEANQSTL ENFLERLKTI MREKYSKCSS |
活性 | The ED50 as determined by the dose-dependent stimulation of human TF-1 cells is ≤ 0.2 ng/ml, corresponding to a specific activity of ≥ 5 x 10^6 units/mg. |
| 產(chǎn)品描述
Recombinant Human IL-4 is a 15.1 kDa globular protein containing 130 amino acid residues.
| 耙標(biāo)信息
Interleukin-4 (IL-4) is a pleiotropic, immune-modulatory cytokine produced by activated T cells, and serves as a ligand for interleukin 4 receptor. IL-4 has been found to have the broadest range of actions. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play an important role in mediating the immune regulatory signal of IL-4. The IL-4 gene, IL-3, IL-5, IL-13, and CSF2 form a cytokine gene cluster on chromosome 5q. In particular, IL-4 is located in close proximity to IL13 on the chromosome. Further, the IL-4 gene, IL13 and IL5 are found to be coordinated by several long-range regulatory elements over a 120 kilobase range on the chromosome. IL-4 delta 2 is a known splice variant of IL-4.
關(guān)鍵字: IL-4;Peprotech;
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